Amany Abdel-Rahman Mohamed
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View article: Palliative effect of taurine against hepatic injury induced by polystyrene microplastics through antioxidant and metabolic pathway modulation in mice
Palliative effect of taurine against hepatic injury induced by polystyrene microplastics through antioxidant and metabolic pathway modulation in mice Open
Introduction Microplastics (MPs), particularly polystyrene microplastics (PS-MPs), are emerging environmental contaminants that have been shown to accumulate in various organs, including the liver, leading to oxidative stress, inflammation…
View article: Access-Related Root Perforation Mishap Correction in a poorly Obturated and Apically Dilacerated Mandibular Second Premolar with a Posttreatment Disease: A Case Report with a 2-Month Follow-up
Access-Related Root Perforation Mishap Correction in a poorly Obturated and Apically Dilacerated Mandibular Second Premolar with a Posttreatment Disease: A Case Report with a 2-Month Follow-up Open
View article: Exploring the CD3/CD56/TNF-α/Caspase3 pathway in pyrethroid-induced immune dysregulation: curcumin-loaded chitosan nanoparticle intervention
Exploring the CD3/CD56/TNF-α/Caspase3 pathway in pyrethroid-induced immune dysregulation: curcumin-loaded chitosan nanoparticle intervention Open
Introduction Conflict reports exist on the impact of pyrethroid insecticides on immune function and the probable underlying mechanisms. Methods This study evaluated the effect of an extensively used pyrethroid insecticide, fenpropathrin (F…
View article: Acrylamide-targeting renal miR−21a−5p/Fibrotic and miR122-5p/ inflammatory signaling pathways and the role of a green approach for nano-zinc detected via in silico and in vivo approaches
Acrylamide-targeting renal miR−21a−5p/Fibrotic and miR122-5p/ inflammatory signaling pathways and the role of a green approach for nano-zinc detected via in silico and in vivo approaches Open
Introduction: Any disruption in renal function can have cascading effects on overall health. Understanding how a heat-born toxicant like acrylamide (ACR) affects kidney tissue is vital for realizing its broader implications for systemic he…
View article: Evaluation of Novel Soybean Genotypes for Yield, Yield components, Seed Quality and Resistance to Cotton Leafworm
Evaluation of Novel Soybean Genotypes for Yield, Yield components, Seed Quality and Resistance to Cotton Leafworm Open
The current study was carried out at the experimental farm of Sakha Agricultural Research Station during 2020 and 2021 seasons. Sixteen soybean promising lines were evaluated for yield, yield components, seed quality and resistance to the …
View article: Exploring the link between pyrethroids exposure and dopaminergic degeneration through morphometric, immunofluorescence, and in-silico approaches: the therapeutic role of chitosan-encapsulated curcumin nanoparticles
Exploring the link between pyrethroids exposure and dopaminergic degeneration through morphometric, immunofluorescence, and in-silico approaches: the therapeutic role of chitosan-encapsulated curcumin nanoparticles Open
Introduction: The synthetic pyrethroid derivative fenpropathrin (FNE), a commonly used insecticide, has been associated with various toxic effects in mammals, particularly neurotoxicity. The study addressed the hallmarks of the pathophysio…
View article: Liposome-Encapsulated Berberine Alleviates Liver Injury in Type 2 Diabetes via Promoting AMPK/mTOR-Mediated Autophagy and Reducing ER Stress: Morphometric and Immunohistochemical Scoring
Liposome-Encapsulated Berberine Alleviates Liver Injury in Type 2 Diabetes via Promoting AMPK/mTOR-Mediated Autophagy and Reducing ER Stress: Morphometric and Immunohistochemical Scoring Open
In the advanced stages of type 2 diabetes mellitus (T2DM), diabetic liver damage is a common complication that can devastate a patient’s quality of life. The present study investigated the ability of liposomal berberine (Lip-BBR) to aid in…
View article: Green Synthesized Zinc Oxide Nanoparticles Using Moringa olifera Ethanolic Extract Lessens Acrylamide-Induced Testicular Damage, Apoptosis, and Steroidogenesis-Related Gene Dysregulation in Adult Rats
Green Synthesized Zinc Oxide Nanoparticles Using Moringa olifera Ethanolic Extract Lessens Acrylamide-Induced Testicular Damage, Apoptosis, and Steroidogenesis-Related Gene Dysregulation in Adult Rats Open
This study assessed the possible protective role of green synthesized zinc oxide nanoparticles using Moringa olifera leaf extract (MO-ZNPs) in acrylamide (ACR)-induced reproductive dysfunctions in male rats. ACR (20 mg/kg b.wt/day) and/or …
View article: Effect of Implementing Nursing Guidelines on Clinical Outcomes for Patients Undergoing Extracorporeal Shock Waves Lithotripsy for Urolithiasis
Effect of Implementing Nursing Guidelines on Clinical Outcomes for Patients Undergoing Extracorporeal Shock Waves Lithotripsy for Urolithiasis Open
Background: Extracorporeal shock wave lithotripsy (ESWL) is non-invasive method for treating kidney stones < 2cm.Aim: This study was conducted to evaluate the effect of implementing nursing guidelines on clinical outcomes for patients unde…
View article: Comparative Assessment of Three Medicinal Plants against Diabetes and Oxidative Stress Using Experimental and Computational Approaches
Comparative Assessment of Three Medicinal Plants against Diabetes and Oxidative Stress Using Experimental and Computational Approaches Open
The hilly and rural areas’ people of Bangladesh have a great history of putting into use numerous traditional medicinal plants to cure diseases. Therefore, with ethanol extract of Molineria capitulata (EEMC), methanol extract of Trichosant…
View article: Evaluation of Antidiabetic Activity of Oxadiazole Derivative in Rats
Evaluation of Antidiabetic Activity of Oxadiazole Derivative in Rats Open
The oxadiazole ring has long been used for the treatment of several diseases. This study aimed to analyze the antihyperglycemic and antioxidant roles of the 1,3,4‐oxadiazole derivative with its toxicity. Diabetes was induced through intrap…
View article: β-Cell Autophagy Pathway and Endoplasmic Reticulum Stress Regulating-Role of Liposomal Curcumin in Experimental Diabetes Mellitus: A Molecular and Morphometric Study
β-Cell Autophagy Pathway and Endoplasmic Reticulum Stress Regulating-Role of Liposomal Curcumin in Experimental Diabetes Mellitus: A Molecular and Morphometric Study Open
Background: Autophagy can confer protection to pancreatic β-cells from the harmful effects of metabolic stress by delaying apoptosis. Curcumin (CUR) alleviates oxidative and endoplasmic reticulum (ER) stress, activates autophagy, reduces i…
View article: The synbiotic mixture of Bacillus licheniformis and Saccharomyces cerevisiae extract aggravates dextran sulfate sodium induced colitis in rats
The synbiotic mixture of Bacillus licheniformis and Saccharomyces cerevisiae extract aggravates dextran sulfate sodium induced colitis in rats Open
Background Uncertain effects of probiotics and/or prebiotics have been reported in experimental and clinical colitis. This study aims to examine the effects of a synbiotic combination comprising Bacillus licheniformis DSM 17236 and Sacchar…
View article: ROLE OF ULTRASOUND IN ASSESSMENT OF ABDOMINAL WALL SWELLINGS
ROLE OF ULTRASOUND IN ASSESSMENT OF ABDOMINAL WALL SWELLINGS Open
The current study concluded that:• Ultrasound had high sensitivity and moderate diagnostic accuracy in evaluating abdominal wall masses.• Ultrasound may limit the patient's exposure to invasive biopsies and to the hazardous exposure to ion…
View article: Concerns with Male Infertility Induced by Exposure to Titanium Nanoparticles and the Supporting Impact of Pelargonium graveolens Essential Oil: Morphometric Records in Male-Wistar Rats
Concerns with Male Infertility Induced by Exposure to Titanium Nanoparticles and the Supporting Impact of Pelargonium graveolens Essential Oil: Morphometric Records in Male-Wistar Rats Open
Background: Due to the increased use of titanium dioxide nanoparticles (TiO2 NPs), the risks of their reprotoxic effect arise. This study anticipated examining the potential protective effects of GEO (geranium essential oil) components scr…
View article: Deciphering the Pharmacological Potentials of Methanol Extract of Sterculia foetida Seeds Using Experimental and Computational Approaches
Deciphering the Pharmacological Potentials of Methanol Extract of Sterculia foetida Seeds Using Experimental and Computational Approaches Open
The edible herb Sterculia foetida L. has potential nutraceutical and medicinal effects. The present study is performed to assess the possible antidiabetic, neuropharmacological, and antidiarrheal activity of the methanolic extract of S. fo…
View article: Neuropharmacological and Antidiabetic Potential of Lannea coromandelica (Houtt.) Merr. Leaves Extract: An Experimental Analysis
Neuropharmacological and Antidiabetic Potential of Lannea coromandelica (Houtt.) Merr. Leaves Extract: An Experimental Analysis Open
The present study examines the neuropharmacological and antidiabetic properties of methanol leaves extract of Lannea coromandelica in animal models. This study is carried out by elevated plus-maze apparatus, motor coordination, thiopental …
View article: Ginkgo biloba: A Treasure of Functional Phytochemicals with Multimedicinal Applications
Ginkgo biloba: A Treasure of Functional Phytochemicals with Multimedicinal Applications Open
Ginkgo biloba is an ancient plant species that is thought to provide a variety of health benefits to living organisms and contains plenty of bioactive components, making it a chemically diversified plant. G. biloba has been shown to have a…
View article: Sustained Functioning Impairments and Oxidative Stress with Neurobehavioral Dysfunction Associated with Oral Nicotine Exposure in the Brain of a Murine Model of Ehrlich Ascites Carcinoma: Modifying the Antioxidant Role of Chlorella vulgaris
Sustained Functioning Impairments and Oxidative Stress with Neurobehavioral Dysfunction Associated with Oral Nicotine Exposure in the Brain of a Murine Model of Ehrlich Ascites Carcinoma: Modifying the Antioxidant Role of Chlorella vulgaris Open
Background: This study provides a model for studying the mechanism(s) responsible for the nervous tissue damage and misfunctioning that occurred due to oral nicotine exposure, considered a stress factor, during the presence of Ehrlich asci…
View article: Time-dependent expression of high-mobility group box-1 and toll-like receptors proteins as potential determinants of skin wound age in rats: Forensic implication
Time-dependent expression of high-mobility group box-1 and toll-like receptors proteins as potential determinants of skin wound age in rats: Forensic implication Open
View article: Stem Cell Transplantation Therapy and Neurological Disorders: Current Status and Future Perspectives
Stem Cell Transplantation Therapy and Neurological Disorders: Current Status and Future Perspectives Open
Neurodegenerative diseases are a global health issue with inadequate therapeutic options and an inability to restore the damaged nervous system. With advances in technology, health scientists continue to identify new approaches to the trea…
View article: Mixture of Plant Growth-Promoting Bacteria Enhanced Growth of Barley Under Salt Stress
Mixture of Plant Growth-Promoting Bacteria Enhanced Growth of Barley Under Salt Stress Open
View article: Appraisal of Bioactive Compounds of Betel Fruit as Antimalarial Agents by Targeting Plasmepsin 1 and 2: A Computational Approach
Appraisal of Bioactive Compounds of Betel Fruit as Antimalarial Agents by Targeting Plasmepsin 1 and 2: A Computational Approach Open
In many countries, the fruit of betel (Piper betle Linn) is traditionally used as medicine for treating malaria. It is a fatal disease, and existing medications are rapidly losing potency, necessitating the development of innovative pharma…
View article: In Silico and In Vitro Evaluation of the Antimicrobial Potential of Bacillus cereus Isolated from Apis dorsata Gut against Neisseria gonorrhoeae
In Silico and In Vitro Evaluation of the Antimicrobial Potential of Bacillus cereus Isolated from Apis dorsata Gut against Neisseria gonorrhoeae Open
Antimicrobial resistance is a major public health and development concern on a global scale. The increasing resistance of the pathogenic bacteria Neisseria gonorrhoeae to antibiotics necessitates efforts to identify potential alternative a…
View article: Effect of Self-Care Practice Health Educational Program for Patients on Urinary Tract Infection Recurrence
Effect of Self-Care Practice Health Educational Program for Patients on Urinary Tract Infection Recurrence Open
View article: The Antioxidant Role of a Taurine-Enriched Diet in Combating the Immunotoxic and Inflammatory Effects of Pyrethroids and/or Carbamates in Oreochromis niloticus
The Antioxidant Role of a Taurine-Enriched Diet in Combating the Immunotoxic and Inflammatory Effects of Pyrethroids and/or Carbamates in Oreochromis niloticus Open
Indiscriminate use of insecticides is a major concern due to its ubiquitous occurrence and potential toxicity to aquatic animals. This study investigated the adverse effects of lambda-cyhalothrin (LCT; C23H19ClF3NO3) and methomyl (MTM; C5H…
View article: Chitosan-Stabilized Selenium Nanoparticles and Metformin Synergistically Rescue Testicular Oxidative Damage and Steroidogenesis-Related Genes Dysregulation in High-Fat Diet/Streptozotocin-Induced Diabetic Rats
Chitosan-Stabilized Selenium Nanoparticles and Metformin Synergistically Rescue Testicular Oxidative Damage and Steroidogenesis-Related Genes Dysregulation in High-Fat Diet/Streptozotocin-Induced Diabetic Rats Open
Background: this study examined the metformin (MF) and/or chitosan stabilized selenium nanoparticles (CH-SeNPs) efficacy to alleviate the male reproductive function impairment in a high-fat diet feed with low-dose streptozotocin (HFD/STZ) …
View article: CJN volume 47 issue 3 Cover and Front matter
CJN volume 47 issue 3 Cover and Front matter Open
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View article: Movement Disorders Due to Selective Basal Ganglia Lesions with Uremia
Movement Disorders Due to Selective Basal Ganglia Lesions with Uremia Open
Background: Basal ganglia (BG) lesions are rarely reported in patients with uremia and may manifest by movement disorders. However, their exact incidence and pathogenesis have not been extensively studied. This study aimed to determine the…
View article: Effect of Implementing Nursing Care on Respiratory Parameters for Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Diseases.
Effect of Implementing Nursing Care on Respiratory Parameters for Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Diseases. Open
Acute exacerbation usually accompanied by increased cough, fever, wheezing, nursing care have been involved in delivering non-pharmacological interventions aimed to reducing symptoms Aim of this study was to evaluate effect of implementing…