Amar Ojha
YOU?
Author Swipe
Developmental variation in dopamine neurobiology, neurocognitive functioning, and impulsivity shape substance use trajectories in youth Open
Theoretical neurodevelopmental models implicate increases in dopamine (DA) function and limitations in neurocognitive control in risk-taking behavior, including substance use, during the transition from adolescence to adulthood. However, d…
View article: Classification of major depressive disorder using vertex-wise brain sulcal depth, curvature, and thickness with a deep and a shallow learning model
Classification of major depressive disorder using vertex-wise brain sulcal depth, curvature, and thickness with a deep and a shallow learning model Open
Major depressive disorder (MDD) is a complex psychiatric disorder that affects the lives of hundreds of millions of individuals around the globe. Even today, researchers debate if morphological alterations in the brain are linked to MDD, l…
View article: Human amygdala nuclei show distinct developmental trajectories from adolescence to adulthood in functional integration with prefrontal circuitry
Human amygdala nuclei show distinct developmental trajectories from adolescence to adulthood in functional integration with prefrontal circuitry Open
Adolescent neurodevelopment of affective and cognitive control, crucial for healthy functioning and impaired transdiagnostically, is supported by refinements between the amygdala and prefrontal cortex (PFC). Due to technical limitations, f…
The Relation between Structural and Functional Connectivity in Adults with ADHD Histories: A Stage 1 Registered Report Open
There is mounting evidence that ADHD is associated with alterations in brain structure and function but it remains unclear how these brain indices relate to each other and correspond to symptom trajectories from childhood into adulthood. I…
The Relation between Structural and Functional Connectivity in Adults with ADHD Histories: A Stage 1 Registered Report Open
There is mounting evidence that ADHD is associated with alterations in brain structure and function but it remains unclear how these brain indices relate to each other and correspond to symptom trajectories from childhood into adulthood. I…
View article: Maturation of striatal dopamine supports the development of habitual behavior through adolescence
Maturation of striatal dopamine supports the development of habitual behavior through adolescence Open
Developmental trajectories during the transition from adolescence to adulthood contribute to the establishment of stable, adult forms of operation. Understanding the neural mechanisms underlying this transition is crucial for identifying v…
Multivariate and regional age-related change in basal ganglia iron in neonates Open
In the perinatal period, reward and cognitive systems begin trajectories, influencing later psychiatric risk. The basal ganglia is important for reward and cognitive processing but early development has not been fully characterized. To ass…
View article: Classification of Major Depressive Disorder Using Vertex-Wise Brain Sulcal Depth, Curvature, and Thickness with a Deep and a Shallow Learning Model
Classification of Major Depressive Disorder Using Vertex-Wise Brain Sulcal Depth, Curvature, and Thickness with a Deep and a Shallow Learning Model Open
Major depressive disorder (MDD) is a complex psychiatric disorder that affects the lives of hundreds of millions of individuals around the globe. Even today, researchers debate if morphological alterations in the brain are linked to MDD, l…
Social threat, fronto-cingulate-limbic morphometry, and symptom course in depressed adolescents: a longitudinal investigation Open
Background Psychosocial stressors characterized by social threat, such as interpersonal loss and social rejection, are associated with depression in adolescents. Few studies, however, have examined whether social threat affects fronto-cing…
Structural brain alterations associated with suicidal thoughts and behaviors in young people: results from 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium Open
Identifying brain alterations associated with suicidal thoughts and behaviors (STBs) in young people is critical to understanding their development and improving early intervention and prevention. The ENIGMA Suicidal Thoughts and Behaviour…
Empathy for others versus for one's child: Associations with mothers’ brain activation during a social cognitive task and with their toddlers’ functioning Open
Caregivers who are higher in dispositional empathy tend to have children with better developmental outcomes; however, few studies have considered the role of child‐directed (i.e., “parental”) empathy, which may be relevant for the caregive…
View article: Multi-site benchmark classification of major depressive disorder using machine learning on cortical and subcortical measures
Multi-site benchmark classification of major depressive disorder using machine learning on cortical and subcortical measures Open
Machine learning (ML) techniques have gained popularity in the neuroimaging field due to their potential for classifying neuropsychiatric disorders. However, the diagnostic predictive power of the existing algorithms has been limited by sm…
Puberty contributes to adolescent development of fronto-striatal functional connectivity supporting inhibitory control Open
Adolescence is defined by puberty and represents a period characterized by neural circuitry maturation (e.g., fronto-striatal systems) facilitating cognitive improvements. Though studies have characterized age-related changes, the extent t…
Empathy for others versus for one's child: Associations with mothers' brain activation during a social cognitive task and with their toddlers' functioning Open
Caregivers who are higher in dispositional empathy tend to have children with better developmental outcomes; however, few studies have considered the role of child-directed (i.e., “parental”) empathy, which may be relevant for the caregive…
View article: Structural brain alterations associated with suicidal thoughts and behaviors in young people: results across 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium
Structural brain alterations associated with suicidal thoughts and behaviors in young people: results across 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium Open
Objective Identifying brain differences associated with suicidal thoughts and behaviors (STBs) in young people is critical to understanding their development and generating effective approaches to early intervention and prevention. The ENI…
Higher Levels of Pro-inflammatory Cytokines Are Associated With Higher Levels of Glutamate in the Anterior Cingulate Cortex in Depressed Adolescents Open
Animal models of stress and related conditions, including depression, have shown that elevated peripheral levels of inflammatory cytokines have downstream consequences on glutamate (Glu) in the brain. Although studies in human adults with …
Study Protocol for Teen Inflammation Glutamate Emotion Research (TIGER) Open
This article provides an overview of the study protocol for the Teen Inflammation Glutamate Emotion Research (TIGER) project, a longitudinal study in which we plan to recruit 60 depressed adolescents (ages 13-18 years) and 30 psychiatrical…
Cerebral blood flow in 5‐ to 8‐month‐olds: Regional tissue maturity is associated with infant affect Open
Infancy is marked by rapid neural and emotional development. The relation between brain function and emotion in infancy, however, is not well understood. Methods for measuring brain function predominantly rely on the BOLD signal; however, …
Virtuous Particularism: The Case for Contextual Value and Moral Sensitivity Open
Principles are often cited as justifications for our actions. In this work, I argue that moral principles are not sensitive enough to contextual considerations given the richness of moral situations. The particularist argues that we should…