Amarpreet Devi
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View article: Efficacy and Safety of Acetyl-L-Carnitine and Agmatine Sulfate Compared to Escitalopram in Major Depressive Disorder: A Double-Blind Study
Efficacy and Safety of Acetyl-L-Carnitine and Agmatine Sulfate Compared to Escitalopram in Major Depressive Disorder: A Double-Blind Study Open
Background: To evaluate the efficacy and safety of FDC containing Acetyl-L-carnitine and Agmatine Sulfate versus Escitalopram in treating Major Depressive Disorder (MDD). Methods: Sixty participants, aged 18-65, diagnosed with MDD, were ra…
View article: A Novel In Vitro Model of the Bone Marrow Microenvironment in Acute Myeloid Leukemia Identifies CD44 and Focal Adhesion Kinase as Therapeutic Targets to Reverse Cell Adhesion-Mediated Drug Resistance
A Novel In Vitro Model of the Bone Marrow Microenvironment in Acute Myeloid Leukemia Identifies CD44 and Focal Adhesion Kinase as Therapeutic Targets to Reverse Cell Adhesion-Mediated Drug Resistance Open
Background/Objectives: Acute myeloid leukemia (AML) is an aggressive neoplasm. Although most patients respond to induction therapy, they commonly relapse due to recurrent disease in the bone marrow microenvironment (BMME). So, the disrupti…
View article: A novel<i>in-vitro</i>model of the bone marrow microenvironment in AML identifies CD44 and Focal Adhesion Kinase as therapeutic targets to reverse cell adhesion-mediated drug resistance
A novel<i>in-vitro</i>model of the bone marrow microenvironment in AML identifies CD44 and Focal Adhesion Kinase as therapeutic targets to reverse cell adhesion-mediated drug resistance Open
Acute myeloid leukemia (AML) is an aggressive neoplasm. Although most patients respond to induction therapy, they commonly relapse due to recurrent disease in the bone marrow microenvironment (BMME). So, disruption of the BMME, releasing t…
View article: Lymphocytosis and chronic lymphocytic leukaemia: investigation and management
Lymphocytosis and chronic lymphocytic leukaemia: investigation and management Open
View article: Multiple myeloma: what a non-haematologist should know
Multiple myeloma: what a non-haematologist should know Open
Multiple myeloma (MM) is a type of haematological bone marrow malignancy. Cancer Research UK reports that MM is the 18th most common cancer in the UK, accounting for 2% of all new cancer cases, yet, non-haematologists often lack familiarit…
View article: Characteristics of L-PRP preparations for treating Achilles tendon rupture within the PATH-2 study
Characteristics of L-PRP preparations for treating Achilles tendon rupture within the PATH-2 study Open
Platelet-rich plasma (PRP) is an autologous preparation that has been claimed to improve healing and mechanobiological properties of tendons both in vitro and in vivo. In this sub-study from the PATH-2 (PRP in Achilles Tendon Healing-2) tr…
View article: Dysregulation of the actin scavenging system and inhibition of DNase activity following severe thermal injury
Dysregulation of the actin scavenging system and inhibition of DNase activity following severe thermal injury Open
Background Circulating cell-free DNA (cfDNA) is not found in healthy subjects, but is readily detected after thermal injury and may contribute to the risk of multiple organ failure. The hypothesis was that a postburn reduction in DNase pro…