Amber J. Clayton
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View article: Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins
Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins Open
(Neuron 95, 896–913; August 16, 2017) It has come to our attention that there is an error in our report regarding the ASD-linked NL3 mutation Arg451Cys and its potential impact on the NL–MDGA interaction. It concerns the paragraph “The ASD…
View article: A synthetic synaptic organizer protein restores glutamatergic neuronal circuits
A synthetic synaptic organizer protein restores glutamatergic neuronal circuits Open
Synthetic excitatory synaptic organizer The human brain contains trillions of synapses within a vast network of neurons. Synapse remodeling is essential to ensure the efficient reception and integration of external stimuli and to store and…
View article: A synthetic synaptic organizer protein restores glutamatergic neuronal circuits
A synthetic synaptic organizer protein restores glutamatergic neuronal circuits Open
Neuronal synapses undergo structural and functional changes throughout life, essential for nervous system physiology. However, these changes may also perturb the excitatory/inhibitory neurotransmission balance and trigger neuropsychiatric …
View article: Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins
Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins Open
View article: Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins
Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins Open
View article: A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability
A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability Open
The discovery of genetic variants influencing sleep patterns can shed light on the physiological processes underlying sleep. As part of a large clinical sequencing project, WGS500, we sequenced a family in which the two male children had s…