Amel M. Soliman
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View article: Liposomal Delivery of Allolobophora caliginosa Coelomic Fluid Attenuates Myocardial Infarction by Suppressing Oxidative Damage, Inflammation, and Apoptosis
Liposomal Delivery of Allolobophora caliginosa Coelomic Fluid Attenuates Myocardial Infarction by Suppressing Oxidative Damage, Inflammation, and Apoptosis Open
View article: Cicer arietinum phytosome ameliorates hepatosteatosis via downregulation of fatty acid synthase and stearoyl-CoA desaturase 1 in rats
Cicer arietinum phytosome ameliorates hepatosteatosis via downregulation of fatty acid synthase and stearoyl-CoA desaturase 1 in rats Open
Background Hepatosteatosis is considered a universal problematic health due to bad lifestyle. Thereby, the current study evaluates the influence of the Cicer arietinum polyunsaturated fatty acids (CAP) and newly synthesized C. arietinum po…
View article: Ameliorative Effect of Galium Verum (Rubiaceae Family) Methanolic Extract on Folic Acid-induced Acute kidney Injury in Male Rats.
Ameliorative Effect of Galium Verum (Rubiaceae Family) Methanolic Extract on Folic Acid-induced Acute kidney Injury in Male Rats. Open
Background: Antioxidant, sedative, anticancer, and antibacterial properties are among the numerous pharmacological characteristics of Galium verum. Aim: The primary goal of this research was to investigate the therapeutic effects of G. ver…
View article: A nano-Liposomal formulation potentiates antioxidant, anti-inflammatory, and fibrinolytic activities of Allolobophora caliginosa coelomic fluid: formulation and characterization
A nano-Liposomal formulation potentiates antioxidant, anti-inflammatory, and fibrinolytic activities of Allolobophora caliginosa coelomic fluid: formulation and characterization Open
Background Coelomic fluid, a pharmacologically active compound in earthworms, exhibits a range of biological activities, including antioxidant, anti-inflammatory, and anticancer. However, the biological activities exerted by the coelomic f…
View article: Antiurolithiatic effect of a polyherbal formulation against sodium oxalate-induced urolithiasis in rats
Antiurolithiatic effect of a polyherbal formulation against sodium oxalate-induced urolithiasis in rats Open
Background The present study assesses the role of polyherbal formula (LACTN) against sodium oxalate (NaOx)—stimulated urolithiasis prophylactic and curative. Forty-eight rats were separated into the following regimen’s groups: Groups I, II…
View article: Therapeutic Efficacy of Anodonta cygnea and Crayfish Procambarus clarkii Hemolymph Extracts on Sepsis-Induced Acute Liver Injury in Neonate Rats
Therapeutic Efficacy of Anodonta cygnea and Crayfish Procambarus clarkii Hemolymph Extracts on Sepsis-Induced Acute Liver Injury in Neonate Rats Open
Background and Objective: In newborns, sepsis is the third highest cause of morbidity and death.The current research intended to assess the efficacy of freshwater mussel Anodonta cygnea and crayfish Procambarus clarkii hemolymph extracts o…
View article: Anti-urolithiatic effect of a polyherbal formulation against sodium oxalate-induced urolithiasis in rats
Anti-urolithiatic effect of a polyherbal formulation against sodium oxalate-induced urolithiasis in rats Open
The present study assesses the role of polyherbal formula (LACTN) against sodium oxalate (NaOx) - stimulated urolithiasis prophylactic and curatively. Forty eight rats were separated into the following regimen’s groups. Groups I, II, III, …
View article: A Coelomic Fluid of Allolobophora caliginosa as Novel Prospects for Medicinal Antioxidants, Anti-inflammatory, Antiproliferative, Analgesics, and Antipyretics
A Coelomic Fluid of Allolobophora caliginosa as Novel Prospects for Medicinal Antioxidants, Anti-inflammatory, Antiproliferative, Analgesics, and Antipyretics Open
Allolobophora caliginosa, an indigenous earthworm of Egypt, has been widely utilized in the pharmaceutical industry because it has many therapeutic properties. These therapeutic properties may be attributed to the earthworm's coelomic flui…
View article: Protective effect of Anodonta cygnea hemolymph against acute kidney injury induced by gentamicin in rats
Protective effect of Anodonta cygnea hemolymph against acute kidney injury induced by gentamicin in rats Open
Background: Anodonta cygnea hemolymph has several pharmacological activities against inflammation, bacteria and tumor. The current study aimed to explore the efficacy of A. cygnea hemolymph against the re…
View article: Protective effect of Anodonta cygnea hemolymph against acute kidney injury induced by gentamicin in rats
Protective effect of Anodonta cygnea hemolymph against acute kidney injury induced by gentamicin in rats Open
Background: Anodonta cygnea hemolymph has several pharmacological activities against inflammation, bacteria and tumor. The current study aimed to explore the efficacy of A. cygnea hemolymph against the renal toxicity induced by Gentamicin …
View article: Spirulina and C-phycocyanin mitigate titanium dioxide nanoparticle-induced hematobiochemical and hepatorenal disorders through antioxidative pathway
Spirulina and C-phycocyanin mitigate titanium dioxide nanoparticle-induced hematobiochemical and hepatorenal disorders through antioxidative pathway Open
View article: Potential Inhibition of Ehrlich Ascites Carcinoma by Naja Nubiae Crude Venom in Swiss Albino Mice
Potential Inhibition of Ehrlich Ascites Carcinoma by Naja Nubiae Crude Venom in Swiss Albino Mice Open
Cancer, the uncontrolled growth of cells, is a noteworthy cause of death globally. The present investigation attempted to study the potential efficacy of the Naja nubiae snake venom (NNSV) against Ehrlich Ascites Carcinoma (EAC) bearing mi…
View article: Silver/chitosan/ascorbic acid nanocomposites ameliorate diabetic nephropathy in the model of type 1 diabetes
Silver/chitosan/ascorbic acid nanocomposites ameliorate diabetic nephropathy in the model of type 1 diabetes Open
Aims: The present study aimed to evaluate anti-diabetic properties of AgNPs/chitosan/ascorbic acid nanocomposites (Ag-NCs) in streptozotocin-induced diabetic rats. Main methods: Eighteen m…
View article: Silver/chitosan/ascorbic acid nanocomposites ameliorate diabetic nephropathy in the model of type 1 diabetes
Silver/chitosan/ascorbic acid nanocomposites ameliorate diabetic nephropathy in the model of type 1 diabetes Open
Aims: The present study aimed to evaluate anti-diabetic properties of AgNPs/chitosan/ascorbic acid nanocomposites (Ag-NCs) in streptozotocin-induced diabetic rats. Main methods: Eighteen male Wistar albino rats were divided into three main…
View article: Antinephrolithiatic activity of Ananas comosus extract against experimentally induced renal calculi in rats.
Antinephrolithiatic activity of Ananas comosus extract against experimentally induced renal calculi in rats. Open
The present study evaluates the prophylactic role of Ananas comosus ethanolic extract (ACEE) against sodium oxalate (NaOx) - induced nephrolithiasis. Forty two rats were allocated into the following set of groups (6 rats/set group). Normal…
View article: Sodium pentobarbital dosages for exsanguination affect biochemical, molecular and histological measurements in rats
Sodium pentobarbital dosages for exsanguination affect biochemical, molecular and histological measurements in rats Open
Rodents are widely used for animal research in Egypt. Pentobarbital is the most common anesthetic agent; however overdoses may affect the experimental outcomes and limit the use of tissues. To investigate the effects of sodium pentobarbita…
View article: Protective effect of Echinochrome against intrahepatic cholestasis induced by alpha-naphthylisothiocyanate in rats
Protective effect of Echinochrome against intrahepatic cholestasis induced by alpha-naphthylisothiocyanate in rats Open
The present study was designed to evaluate the protective effects of echinochrome (Ech) on intrahepatic cholestasis in rats induced by a single (i.p.) injection of alpha-naphthylisothiocyanate (ANIT) (75 mg/kg body weight). The rats were p…
View article: Protective effect of Echinochrome against intrahepatic cholestasis induced by alpha-naphthylisothiocyanate in rats
Protective effect of Echinochrome against intrahepatic cholestasis induced by alpha-naphthylisothiocyanate in rats Open
The present study was designed to evaluate the protective effects of echinochrome (Ech) on intrahepatic cholestasis in rats induced by a single (i.p.) injection of alpha-naphthylisothiocyanate (ANIT) (75 mg/kg body weight). The rats were p…
View article: Protective effect of Echinochrome against intrahepatic cholestasis induced by alpha-naphthylisothiocyanate in rats
Protective effect of Echinochrome against intrahepatic cholestasis induced by alpha-naphthylisothiocyanate in rats Open
The present study was designed to evaluate the protective effects of echinochrome (Ech) on intrahepatic cholestasis in rats induced by a single (i.p.) injection of alpha-naphthylisothiocyanate (ANIT) (75 mg/kg body weight). The rats were p…
View article: Effectiveness of<i>Coelatura aegyptiaca</i>Extract Combination with Atorvastatin on Experimentally Induced Hyperlipidemia in Rats
Effectiveness of<i>Coelatura aegyptiaca</i>Extract Combination with Atorvastatin on Experimentally Induced Hyperlipidemia in Rats Open
Background . The present study aimed to assess the effectiveness of clam extract in combination with atorvastatin against experimentally hyperlipidemia in rats. Method . Forty male rats were divided into 5 groups (8 rats /group): control, …
View article: Effects of 3 Rodent Beddings on Biochemical Measures in Rats and Mice
Effects of 3 Rodent Beddings on Biochemical Measures in Rats and Mice Open
Components of bedding might interact with experimental treatments and affect the outcome of various experiments. Here we studied the biochemical effects of 3 rodent bedding materials that are commonly used in Egypt. Male and female rats an…
View article: Echinochrome pigment attenuates diabetic nephropathy in the models of type 1 and type 2 diabetes
Echinochrome pigment attenuates diabetic nephropathy in the models of type 1 and type 2 diabetes Open
Background. The main complication of diabetes mellitus is diabetic nephropathy in both types, which is a main reason for renal failure. Echinochrome substance present in sea urchin shells and spines and possesses high antioxidant activity.…
View article: PROSPECTIVE EFFECT OF RED ALGAE,ACTINOTRICHIA FRAGILIS, AGAINST SOME OSTEOARTHRITISAETIOLOGY
PROSPECTIVE EFFECT OF RED ALGAE,ACTINOTRICHIA FRAGILIS, AGAINST SOME OSTEOARTHRITISAETIOLOGY Open
AFP and AFG may have the potency to become the therapeutic candidate for OA disease as it prevents the key causes of OA initiation.
View article: ANTIULCEROGENIC EFFICACY OF ETHANOLIC EXTRACT OF VITIS VINIFERA LEAVES IN RATS
ANTIULCEROGENIC EFFICACY OF ETHANOLIC EXTRACT OF VITIS VINIFERA LEAVES IN RATS Open
Objective: The ethanolic extract of Vitis vinifera leaves (VVE) (500 mg/kg body weight), ranitidine (50 mg/kg body weight) and both of them were tested for their gastroprotective and curative effects against the i…
View article: Origanum majorana Attenuates Nephrotoxicity of Cisplatin Anticancer Drug through Ameliorating Oxidative Stress
Origanum majorana Attenuates Nephrotoxicity of Cisplatin Anticancer Drug through Ameliorating Oxidative Stress Open
Despite the fact that cisplatin is an important anticancer drug, its clinical utilization is limited by nephrotoxicity during long term medication. Combined cisplatin chemotherapy with plant extracts can diminish toxicity and enhance the a…
View article: Potential impact of Paracentrotus lividus extract on diabetic rat models induced by high fat diet/streptozotocin
Potential impact of Paracentrotus lividus extract on diabetic rat models induced by high fat diet/streptozotocin Open
View article: New Insights into Sepsis Therapy Using Sepia Officinalis
New Insights into Sepsis Therapy Using Sepia Officinalis Open
SOBT and SOP had profound antiseptic efficacy.
View article: Anti-HB Core Screening Significance among Healthy Blood Donors in Fayoum, Egypt
Anti-HB Core Screening Significance among Healthy Blood Donors in Fayoum, Egypt Open
Background: Occult Hepatitis B is the existence of HBV-DNA in the serum of HBsAg negative cases with or without the presence of antibodies to HBV. Although (HBV)transmission viahepatitisB surface antigen (HBsAg) negative blood donors …
View article: Supplementary Material for: Prevalence and Symptomatic Burden of Diagnosed Endometriosis in the United States: National Estimates from a Cross-Sectional Survey of 59,411 Women
Supplementary Material for: Prevalence and Symptomatic Burden of Diagnosed Endometriosis in the United States: National Estimates from a Cross-Sectional Survey of 59,411 Women Open
Background/Aims: To estimate the prevalence of diagnosed endometriosis (DE) in women in the United States and assess the associated symptomatic burden. Methods: An online, cross-sectional survey of women aged 18-49 years was …