A. Edwards
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View article: High-throughput identification of Toxoplasma gondii effector proteins that target host cell transcription
High-throughput identification of Toxoplasma gondii effector proteins that target host cell transcription Open
View article: Independent SARS-CoV-2 staff testing protected academic and health-care institutions in northwest London
Independent SARS-CoV-2 staff testing protected academic and health-care institutions in northwest London Open
View article: Mapping host-microbe transcriptional interactions by dual perturb-seq
Mapping host-microbe transcriptional interactions by dual perturb-seq Open
SUMMARY Intracellular pathogens and other endosymbionts reprogram host cell transcription to suppress immune responses and recalibrate biosynthetic pathways. This reprogramming is critical in determining the outcome of infection or colonis…
View article: High-Power Test of Two Prototype X-Band Accelerating Structures Based on SwissFEL Fabrication Technology
High-Power Test of Two Prototype X-Band Accelerating Structures Based on SwissFEL Fabrication Technology Open
This article presents the design, construction, and high-power test of two $X$-band radio frequency (RF) accelerating structures built as part of a collaboration between CERN and the Paul Scherrer Institute (PSI) for the compact linear col…
View article: Timeliness and Quality of Response to Referrals Received by a Psychiatry Liaison Service for Older Adults During a Pandemic
Timeliness and Quality of Response to Referrals Received by a Psychiatry Liaison Service for Older Adults During a Pandemic Open
Aims To improve timeliness of response and provide a committed plan to referrals received by the liaison service for older adults in Croydon University Hospital. Background: A quality improvement project in 2019 aimed to evaluate effective…
View article: Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population
Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population Open
Neural stem cell numbers fall rapidly in the hippocampus of juvenile mice but stabilize during adulthood, ensuring lifelong hippocampal neurogenesis. We show that this stabilization of stem cell numbers in young adults is the result of coo…
View article: Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy
Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy Open
View article: Author Correction: Scalable and robust SARS-CoV-2 testing in an academic center
Author Correction: Scalable and robust SARS-CoV-2 testing in an academic center Open
View article: Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Open
View article: Scalable and robust SARS-CoV-2 testing in an academic center
Scalable and robust SARS-CoV-2 testing in an academic center Open
View article: Kit-free automated RNA extraction for SARS-CoV-2 testing v1
Kit-free automated RNA extraction for SARS-CoV-2 testing v1 Open
Purpose of examination / Clinical relevance At the end of 2019, several pneumonia cases were reported in Wuhan, China and the pathogen was confirmed as a new viral strain. World Health organization has named the newly identified coronaviru…
View article: Automated transfer of inactivated virus samples from individual 2ml tubes to 96-well plate v1
Automated transfer of inactivated virus samples from individual 2ml tubes to 96-well plate v1 Open
Purpose of examination / Clinical relevance At the end of 2019, several pneumonia cases were reported in Wuhan, China and the pathogen was confirmed as a new viral strain. World Health organization has named the newly identified coronaviru…
View article: GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells
GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells Open
View article: Progressive changes in hippocampal stem cell properties ensure lifelong neurogenesis
Progressive changes in hippocampal stem cell properties ensure lifelong neurogenesis Open
SUMMARY Neural stem cell numbers fall rapidly in the hippocampus of juvenile mice but stabilise during adulthood, ensuring lifelong hippocampal neurogenesis. We show that this reduction in stem cell depletion rate is the result of multiple…
View article: Investigating Instructor Talk in Novel Contexts: Widespread Use, Unexpected Categories, and an Emergent Sampling Strategy
Investigating Instructor Talk in Novel Contexts: Widespread Use, Unexpected Categories, and an Emergent Sampling Strategy Open
Instructor Talk—noncontent language used by instructors in classrooms—is a recently defined and promising variable for better understanding classroom dynamics. Having previously characterized the Instructor Talk framework within the contex…
View article: Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord
Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord Open
The coordinated spatial and temporal regulation of gene expression in the vertebrate neural tube determines the identity of neural progenitors and the function and physiology of the neurons they generate. Progress has been made deciphering…
View article: Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord
Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord Open
The coordinated spatial and temporal regulation of gene expression in the vertebrate neural tube determines the identity of neural progenitors and the function and physiology of the neurons they generate. Progress has been made deciphering…