Amelia K. Ryan
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View article: Multiplexed Molecularly-Specific SWCNT Cytokine Sensing is Enabled and Enhanced by Amine-Functionalized DNA Aqueous Two-Phase Extraction
Multiplexed Molecularly-Specific SWCNT Cytokine Sensing is Enabled and Enhanced by Amine-Functionalized DNA Aqueous Two-Phase Extraction Open
Single-walled carbon nanotubes (SWCNT) are versatile building blocks for optical sensors. Their carbon lattice structure, denoted by chiral (n,m) indices, determines the wavelength of their near infrared fluorescence emission. Commercially…
View article: A near-infrared fluorescent aptananosensor enables selective detection of the stress hormone cortisol in artificial cerebrospinal fluid
A near-infrared fluorescent aptananosensor enables selective detection of the stress hormone cortisol in artificial cerebrospinal fluid Open
In this study, we used carbon nanotubes and a ssDNA aptamer to design a fluorescent sensor to detect cortisol, which we showed we could do in a selective manner compared to estradiol and could do in artificial cerebrospinal fluid.
View article: Optical Aptamer-Based Cytokine Nanosensor Detects Macrophage Activation by Bacterial Toxins
Optical Aptamer-Based Cytokine Nanosensor Detects Macrophage Activation by Bacterial Toxins Open
Overactive or dysregulated cytokine expression is a hallmark of many acute and chronic inflammatory diseases. This is true for acute or chronic infections, neurodegenerative diseases, autoimmune diseases, cardiovascular diseases, cancer, a…
View article: Noninvasive Injectable Optical Nanosensor‐Hydrogel Hybrids Detect Doxorubicin in Living Mice
Noninvasive Injectable Optical Nanosensor‐Hydrogel Hybrids Detect Doxorubicin in Living Mice Open
While the tissue‐transparent fluorescence of single‐walled carbon nanotubes (SWCNTs) imparts substantial potential for use in non‐invasive biosensors, the development of non‐invasive systems is yet to be realized. Here, the functionality o…
View article: An optical aptamer-based cytokine nanosensor detects macrophage activation by bacterial toxins
An optical aptamer-based cytokine nanosensor detects macrophage activation by bacterial toxins Open
Overactive or dysregulated cytokine expression is hallmark of many acute and chronic inflammatory diseases. This is true for acute or chronic infection, neurodegenerative diseases, autoimmune diseases, cardiovascular disease, cancer, and o…