Asim Shabbir
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View article: International expert consensus on surgery for type 2 diabetes mellitus
International expert consensus on surgery for type 2 diabetes mellitus Open
This Delphi expert consensus statement guides clinicians on various aspects of metabolic surgery for T2DM and also grades the quality of the available evidence for each of the proposed statements.
View article: Empowering weight loss: a pragmatic randomized controlled trial of a theory-driven self-regulation mobile app for young adults with excess body weight
Empowering weight loss: a pragmatic randomized controlled trial of a theory-driven self-regulation mobile app for young adults with excess body weight Open
Background/Introduction Obesity is projected to affect more than half of the global population by 2035, posing significant health and economic challenges. While lifestyle modification is considered a cornerstone of weight management, its e…
View article: International expert consensus on the current status and future prospects of artificial intelligence in metabolic and bariatric surgery
International expert consensus on the current status and future prospects of artificial intelligence in metabolic and bariatric surgery Open
Artificial intelligence (AI) is transforming the landscape of medicine, including surgical science and practice. The evolution of AI from rule-based systems to advanced machine learning and deep learning algorithms has opened new avenues f…
View article: Empowering weight loss through a self-regulation app-based program on weight loss among young adults with excess body weight: A pragmatic randomized controlled trial (Preprint)
Empowering weight loss through a self-regulation app-based program on weight loss among young adults with excess body weight: A pragmatic randomized controlled trial (Preprint) Open
BACKGROUND By 2035, over half of the global population may be obese, driving significant health and economic burdens. Although lifestyle modification is a preferred approach to weight management, it requires substantial support to be effe…
View article: Comparison Of The Clinical Efficacy Of Linagliptin With SGLT2 Inhibitors In Diabetic Patients: A Comparative Cross-Sectional Study From Pakistan
Comparison Of The Clinical Efficacy Of Linagliptin With SGLT2 Inhibitors In Diabetic Patients: A Comparative Cross-Sectional Study From Pakistan Open
This study compares linagliptin and SGLT-2 inhibitors to optimize diabetes management by evaluating their glycemic and non-glycemic effects. A cross-sectional study was conducted at the Aga Khan University Hospital, Karachi, from May to Oc…
View article: BEHIND THE BURDEN: A QUALITATIVE STUDY ON CAREGIVING FOR SUBSTANCE USE DISORDER IN PAKISTAN
BEHIND THE BURDEN: A QUALITATIVE STUDY ON CAREGIVING FOR SUBSTANCE USE DISORDER IN PAKISTAN Open
Background: Substance Use Disorder (SUD) poses severe challenges for both individuals with addiction and their caregivers. Caregivers in Pakistan experience psychological distress together with economic hardship and social discrimination w…
View article: Cerebellopontine angle paraganglioma masquerading as vestibular schwannoma
Cerebellopontine angle paraganglioma masquerading as vestibular schwannoma Open
Paragangliomas are slow-growing, extra-adrenal neuroendocrine tumors with rare intracranial presentation. Although benign, they can be locally aggressive tumors causing bone destruction and compression related symptoms. We report the case …
View article: Feasibility of long-range telesurgical robotic radical gastrectomy in a live porcine model
Feasibility of long-range telesurgical robotic radical gastrectomy in a live porcine model Open
Background: Telesurgery has been made increasingly possible with the advancements in robotic surgical platforms and network connectivity. However, long-distance transnational complex robotic surgeries such as gastrectomy have yet to be att…
View article: Determinants of quality of life and emotional well‐being in a bariatric surgery seeking cohort of 1501 multi‐ethnic Asian patients
Determinants of quality of life and emotional well‐being in a bariatric surgery seeking cohort of 1501 multi‐ethnic Asian patients Open
Summary Objective The relationship between ethnicity, obesity and health‐related quality of life outcomes in a multi‐ethnic population remains poorly understood. We aim to investigate the relationship between ethnicity, body mass index (BM…
View article: Impact of surgical and non-surgical weight loss on echocardiographic and strain parameters in Asian patients
Impact of surgical and non-surgical weight loss on echocardiographic and strain parameters in Asian patients Open
Surgical weight loss (SWL) improves myocardial mechanics as measured by speckle-tracking imaging. However non-surgical versus SWL and the subsequent impact on myocardial function in overweight Asian subjects has not been evaluated. 66 pati…
View article: Phase I PIANO trial—PIPAC-oxaliplatin and systemic nivolumab combination for gastric cancer peritoneal metastases: clinical and translational outcomes
Phase I PIANO trial—PIPAC-oxaliplatin and systemic nivolumab combination for gastric cancer peritoneal metastases: clinical and translational outcomes Open
The first-in-human trial combining PIPAC-OX and nivolumab demonstrated safety and tolerability, coupled with enhanced T-cell infiltration within peritoneal tumors. This trial sets the stage for future combinations of systemic immunotherapy…
View article: Correction: Effectiveness of an Artificial Intelligence-Assisted App for Improving Eating Behaviors: Mixed Methods Evaluation
Correction: Effectiveness of an Artificial Intelligence-Assisted App for Improving Eating Behaviors: Mixed Methods Evaluation Open
[This corrects the article DOI: 10.2196/46036.].
View article: Correction: Effectiveness of an Artificial Intelligence-Assisted App for Improving Eating Behaviors: Mixed Methods Evaluation (Preprint)
Correction: Effectiveness of an Artificial Intelligence-Assisted App for Improving Eating Behaviors: Mixed Methods Evaluation (Preprint) Open
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View article: Prevalence of contrast-induced acute kidney injury after primary percutaneous coronary intervention: A systematic review
Prevalence of contrast-induced acute kidney injury after primary percutaneous coronary intervention: A systematic review Open
Background: Contrast-induced acute kidney injury (CIN) is a frequent side effect of percutaneous coronary intervention (PCI) that is linked to increased rates of death and morbidity as well as extended hospital stays in patients with cardi…
View article: Impact of surgical and non-surgical weight loss on echocardiographic and strain parameters in Asian patients
Impact of surgical and non-surgical weight loss on echocardiographic and strain parameters in Asian patients Open
Objective: Surgical weight loss (SWL) improves myocardial mechanics as measured by speckle-tracking imaging. However non-surgical versus SWL and the subsequent impact on myocardial function in overweight Asian subjects has not been evaluat…
View article: Sex differences in optimal medical therapy following invasive angiography for coronary artery disease
Sex differences in optimal medical therapy following invasive angiography for coronary artery disease Open
Funding Acknowledgements Type of funding sources: Other. Main funding source(s): HARP Wellcome Trust PhD Fellowship Grant & NIHR Biomedical Research Centre Introduction Coronary artery disease (CAD) remains the number one cause of death in…
View article: Spatially resolved niche and tumor microenvironmental alterations in gastric cancer peritoneal metastases
Spatially resolved niche and tumor microenvironmental alterations in gastric cancer peritoneal metastases Open
Peritoneal metastases (PM) in gastric cancer (GC) portend a poor prognosis, yet our understanding of tumor microenvironmental (TME) characteristics associated with GCPM remain limited. Here, we analyzed intrinsic genomic alterations and tr…
View article: Effectiveness of an Artificial Intelligence-Assisted App for Improving Eating Behaviors: Mixed Methods Evaluation
Effectiveness of an Artificial Intelligence-Assisted App for Improving Eating Behaviors: Mixed Methods Evaluation Open
Background A plethora of weight management apps are available, but many individuals, especially those living with overweight and obesity, still struggle to achieve adequate weight loss. An emerging area in weight management is the support …
View article: Public acceptance of using artificial intelligence-assisted weight management apps in high-income southeast Asian adults with overweight and obesity: a cross-sectional study
Public acceptance of using artificial intelligence-assisted weight management apps in high-income southeast Asian adults with overweight and obesity: a cross-sectional study Open
Introduction With in increase in interest to incorporate artificial intelligence (AI) into weight management programs, we aimed to examine user perceptions of AI-based mobile apps for weight management in adults with overweight and obesity…
View article: Unveiling the prognostic significance of malignant ascites in advanced gastrointestinal cancers: a marker of peritoneal carcinomatosis burden
Unveiling the prognostic significance of malignant ascites in advanced gastrointestinal cancers: a marker of peritoneal carcinomatosis burden Open
Background: Ascites is common in advanced gastrointestinal cancers with peritoneal metastases (PM) and negatively impacts patient survival. No study to date has specifically evaluated the relationship between ascites, PM and survival outco…
View article: Low molecular weight heparin use and thrombotic complications in upper gastrointestinal resection for malignancy in a multi-ethnic Asian population
Low molecular weight heparin use and thrombotic complications in upper gastrointestinal resection for malignancy in a multi-ethnic Asian population Open
Incidence of venous thromboembolism was low and similar irrespective of postoperative LMWH use. However, LMWH use was associated with increased postoperative bleeding. Hence, we do not support routine LMWH for Asian patients undergoing UGI…
View article: Determinants of quality of life and emotional well-being in a prospective bariatric cohort of 1501 multi-ethnic Asian patients
Determinants of quality of life and emotional well-being in a prospective bariatric cohort of 1501 multi-ethnic Asian patients Open
Objective:The relationship between ethnicity, obesity and health-related quality of life (HR-QoL) outcomes in a multi-ethnic population remain poorly understood. We aim to investigate the relationship between ethnicity, body mass index (BM…
View article: Socio-Demographic, Behavioral and Psychological Factors Associated with High BMI among Adults in a Southeast Asian Multi-Ethnic Society: A Structural Equation Model
Socio-Demographic, Behavioral and Psychological Factors Associated with High BMI among Adults in a Southeast Asian Multi-Ethnic Society: A Structural Equation Model Open
While various influencing factors of overweight and obesity have been identified, the underlying mechanism remains unclear. We examined the relationships among sociodemographic, behavioral, and psychological factors on anthropometry in a m…