Amina Ben Mihoub
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View article: Neuroprotective Effect of Curcumin-Loaded RGD Peptide-PEGylated Nanoliposomes
Neuroprotective Effect of Curcumin-Loaded RGD Peptide-PEGylated Nanoliposomes Open
Curcumin is known for its anti-inflammatory, neuroprotective, and antioxidant properties, but its use in biological applications is hindered by its sensitivity to light, oxygen, and temperature. Furthermore, due to its low water solubility…
View article: Peptide-conjugated nanoparticles for targeted photodynamic therapy
Peptide-conjugated nanoparticles for targeted photodynamic therapy Open
Cancer is the second leading cause of death worldwide after cardiovascular disease. Depending on the type and the location of the tumor, several cancer treatments are implemented. Among these, the three most conventional therapies are surg…
View article: Synthesis of New Water Soluble β-Cyclodextrin@Curcumin Conjugates and In Vitro Safety Evaluation in Primary Cultures of Rat Cortical Neurons
Synthesis of New Water Soluble β-Cyclodextrin@Curcumin Conjugates and In Vitro Safety Evaluation in Primary Cultures of Rat Cortical Neurons Open
Self-aggregation of Curcumin (Cur) in aqueous biological environment decreases its bioavailability and in vivo therapeutic efficacy, which hampers its clinical use as candidate for reducing risk of neurodegenerative diseases. Here, we focu…
View article: Fighting Hypoxia to Improve PDT
Fighting Hypoxia to Improve PDT Open
Photodynamic therapy (PDT) has drawn great interest in recent years mainly due to its low side effects and few drug resistances. Nevertheless, one of the issues of PDT is the need for oxygen to induce a photodynamic effect. Tumours often h…
View article: Use of Cyclodextrins in Anticancer Photodynamic Therapy Treatment
Use of Cyclodextrins in Anticancer Photodynamic Therapy Treatment Open
Photodynamic therapy (PDT) is mainly used to destroy cancerous cells; it combines the action of three components: a photoactivatable molecule or photosensitizer (PS), the light of an appropriate wavelength, and naturally occurring molecula…