Amira Bryll
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View article: Thalamic and cerebral white matter volumes allow for identification of cognitively impaired patients with early relapsing-remitting multiple sclerosis
Thalamic and cerebral white matter volumes allow for identification of cognitively impaired patients with early relapsing-remitting multiple sclerosis Open
Thalamic and cerebral white matter volumes measured on T1-weighted brain MRI allow for identification of cognitively impaired RRMS patients in a real-world clinical setting.
View article: The role of the cardiothoracic ratio in the screening of left ventricular hypertrophy in arterial hypertension: a systematic review
The role of the cardiothoracic ratio in the screening of left ventricular hypertrophy in arterial hypertension: a systematic review Open
The presence of hypertensive left ventricular hypertrophy (LVH) is a risk feature associated with both cardiovascular morbidity and mortality. The aim of this review was to evaluate the available data about the diagnostic value of the card…
View article: Cardiac Magnetic Resonance Imaging in Diagnostics and Cardiovascular Risk Assessment
Cardiac Magnetic Resonance Imaging in Diagnostics and Cardiovascular Risk Assessment Open
Cardiac magnetic resonance (CMR) allows for analysis of cardiac function and myocardial tissue characterization. Increased left ventricular mass (LVM) is an independent predictor of cardiovascular events; however, the diagnosis of left ven…
View article: Divergent pattern of functional connectivity within the dorsal attention network differentiates schizophrenia and bipolar disorder patients
Divergent pattern of functional connectivity within the dorsal attention network differentiates schizophrenia and bipolar disorder patients Open
Introduction Schizophrenia (SZ) and bipolar disorder (BD) share common clinical features, symptoms, and neurocognitive deficits, which results in common misdiagnosis. Recently, it has been suggested that alterations within brain networks a…
View article: Myo-inositol’s Role in Understanding the Pain Perception in Patients with Schizophrenia
Myo-inositol’s Role in Understanding the Pain Perception in Patients with Schizophrenia Open
The molecular explanation for the changes in pain perception in schizophrenia lies in nerve inflammation. The decrease in inositol, mainly localized in glial cells, can support these changes. There are also significant alterations in the v…
View article: Prominent crista terminalis mimicking a right atrial mass: a systematic literature review and meta-analysis
Prominent crista terminalis mimicking a right atrial mass: a systematic literature review and meta-analysis Open
The crista terminalis is an anatomical structure localized on the posterolateral wall of the right atrium (RA). We performed a systematic review of the literature and meta-analysis concerning cases of unusual prominent crista terminalis mi…
View article: Association of Blood Metabolomics Biomarkers with Brain Metabolites and Patient-Reported Outcomes as a New Approach in Individualized Diagnosis of Schizophrenia
Association of Blood Metabolomics Biomarkers with Brain Metabolites and Patient-Reported Outcomes as a New Approach in Individualized Diagnosis of Schizophrenia Open
Given its polygenic nature, there is a need for a personalized approach to schizophrenia. The aim of the study was to select laboratory biomarkers from blood, brain imaging, and clinical assessment, with an emphasis on patients’ self-repor…
View article: Benefits and Meaning of Lipids Profile in Relation to Oxidative Balance and Brain Morphology in Schizophrenia
Benefits and Meaning of Lipids Profile in Relation to Oxidative Balance and Brain Morphology in Schizophrenia Open
Schizophrenia is characterized by complex metabolic dysregulations and their consequences. Until now, numerous theories have explained its pathogenesis, using a spectrum of available technologies. We focused our interest on lipid profile—p…
View article: The Association of the Oral Microbiota with the Effects of Acid Stress Induced by an Increase of Brain Lactate in Schizophrenia Patients
The Association of the Oral Microbiota with the Effects of Acid Stress Induced by an Increase of Brain Lactate in Schizophrenia Patients Open
The altered cerebral energy metabolism central to schizophrenia can be linked to lactate accumulation. Lactic acid is produced by gastrointestinal bacteria, among others, and readily crosses the blood–brain barrier, leading to the brain ac…
View article: Clinical Data, Chest Radiograph and Electrocardiography in the Screening for Left Ventricular Hypertrophy: The CAR2E2 Score
Clinical Data, Chest Radiograph and Electrocardiography in the Screening for Left Ventricular Hypertrophy: The CAR2E2 Score Open
Left ventricular hypertrophy (LVH) is associated with adverse clinical outcomes and implicates clinical decision-making. The aim of our study was to assess the importance of different approaches in the screening for LVH. We included patien…
View article: Redefining the Cut-Off Ranges for TSH Based on the Clinical Picture, Results of Neuroimaging and Laboratory Tests in Unsupervised Cluster Analysis as Individualized Diagnosis of Early Schizophrenia
Redefining the Cut-Off Ranges for TSH Based on the Clinical Picture, Results of Neuroimaging and Laboratory Tests in Unsupervised Cluster Analysis as Individualized Diagnosis of Early Schizophrenia Open
Thyroid abnormalities, including mild forms of hypothyroidism and hyperthyroidism, are reported as risk factors for the development of a number of neuropsychiatric disorders, including schizophrenia. The diagnostic process still takes into…
View article: Differences among COVID-19, Bronchopneumonia and Atypical Pneumonia in Chest High Resolution Computed Tomography Assessed by Artificial Intelligence Technology
Differences among COVID-19, Bronchopneumonia and Atypical Pneumonia in Chest High Resolution Computed Tomography Assessed by Artificial Intelligence Technology Open
The aim of this study was to compare the results of automatic assessment of high resolution computed tomography (HRCT) by artificial intelligence (AI) in 150 patients from three subgroups: pneumonia in the course of COVID-19, bronchopneumo…
View article: Time-Frequency Characterization of Resting Brain in Bipolar Disorder during Euthymia—A Preliminary Study
Time-Frequency Characterization of Resting Brain in Bipolar Disorder during Euthymia—A Preliminary Study Open
The goal of this paper is to investigate the baseline brain activity in euthymic bipolar disorder (BD) patients by comparing it to healthy controls (HC) with the use of a variety of resting state functional magnetic resonance imaging (rs-f…
View article: COVID-19 Infection Negative in Nasopharyngeal Swabs but Suspected in Computed Tomography and Confirmed in Bronchoalveolar Lavage Material
COVID-19 Infection Negative in Nasopharyngeal Swabs but Suspected in Computed Tomography and Confirmed in Bronchoalveolar Lavage Material Open
We present a case of a patient with clinical symptoms of pneumonia, negative in several polymerase chain reaction COVID-19 tests from nasopharyngeal swabs but suspected in computed tomography and finally confirmed in bronchoalveolar lavage…
View article: Determinants of Schizophrenia Endophenotypes Based on Neuroimaging and Biochemical Parameters
Determinants of Schizophrenia Endophenotypes Based on Neuroimaging and Biochemical Parameters Open
Despite extensive research, there is no convincing evidence of a reliable diagnostic biomarker for schizophrenia beyond clinical observation. Disorders of glutamatergic neurotransmission associated with N-methyl-D-aspartate (NMDA) receptor…
View article: Olfactory Dysfunction in Patients With Relapsing-Remitting Multiple Sclerosis Treated With Disease-Modifying Therapies
Olfactory Dysfunction in Patients With Relapsing-Remitting Multiple Sclerosis Treated With Disease-Modifying Therapies Open
Background: Olfactory dysfunction evaluated with time-consuming tests was more common in patients with multiple sclerosis (MS) than in controls and correlated with neurological deficit. The aim of the present study was to compare olfactory…
View article: Altered Functional Connectivity Differences in Salience Network as a Neuromarker of Suicide Risk in Euthymic Bipolar Disorder Patients
Altered Functional Connectivity Differences in Salience Network as a Neuromarker of Suicide Risk in Euthymic Bipolar Disorder Patients Open
Obtained results suggest the association between risk of suicide and activity of regions responsible for functions such as learning from mistakes, prospective thinking, and sensory integration.
View article: The Relationship between the Level of Anterior Cingulate Cortex Metabolites, Brain-Periphery Redox Imbalance, and the Clinical State of Patients with Schizophrenia and Personality Disorders
The Relationship between the Level of Anterior Cingulate Cortex Metabolites, Brain-Periphery Redox Imbalance, and the Clinical State of Patients with Schizophrenia and Personality Disorders Open
Schizophrenia is a complex mental disorder whose course varies with periods of deterioration and symptomatic improvement without diagnosis and treatment specific for the disease. So far, it has not been possible to clearly define what kind…
View article: Differences in Sweet Taste Perception and Its Association with the Streptococcus mutans Cariogenic Profile in Preschool Children with Caries
Differences in Sweet Taste Perception and Its Association with the Streptococcus mutans Cariogenic Profile in Preschool Children with Caries Open
The aim of the study was to verify the hypothesis about differences in sweet taste perception in the group of preschool children with and without caries, and to determine its relationship with cariogenic microbiota and the frequency of swe…
View article: Electrocardiography and cardiac magnetic resonance imaging in the detection of left ventricular hypertrophy: the impact of indexing methods
Electrocardiography and cardiac magnetic resonance imaging in the detection of left ventricular hypertrophy: the impact of indexing methods Open
Thediagnosis of LVH strongly depends on ECG- and CMR‑based definitions. ThePeguero-Lo Presti criterion and the Cornell criteria, which are sex‑specific, may provide the highest level of diagnostic accuracy and should be considered when scr…
View article: Oxidative-Antioxidant Imbalance and Impaired Glucose Metabolism in Schizophrenia
Oxidative-Antioxidant Imbalance and Impaired Glucose Metabolism in Schizophrenia Open
Schizophrenia is a neurodevelopmental disorder featuring chronic, complex neuropsychiatric features. The etiology and pathogenesis of schizophrenia are not fully understood. Oxidative-antioxidant imbalance is a potential determinant of sch…
View article: Ischemic and non-ischemic patterns of late gadolinium enhancement in heart failure with reduced ejection fraction
Ischemic and non-ischemic patterns of late gadolinium enhancement in heart failure with reduced ejection fraction Open
Among HF patients with LVEF ≤ 35%, clinical factors including older age, CAD, and previous MI are associated with transmural LGE in the posterolateral wall, while CAD is associated with LGE. This data may have potential implications for pl…
View article: Computed Tomography Assessment of Brain Atrophy in Centenarians
Computed Tomography Assessment of Brain Atrophy in Centenarians Open
The aim of our study was to compare the degree of brain atrophy in centenarians and in seniors 70–99 years old. The study group consisted of 23 patients aged 100–106 years. The control group consisted of 90 patients, 30 in each age subgrou…
View article: Changes in the Selected Antioxidant Defense Parameters in the Blood of Patients after High Resolution Computed Tomography
Changes in the Selected Antioxidant Defense Parameters in the Blood of Patients after High Resolution Computed Tomography Open
Ionizing radiation generated during high resolution computed tomography (HRCT) scanning may have an indirect effect on the mechanisms regulating the oxidative-antioxidant balance in the human body, which is one of the necessary factors ens…
View article: Selected risk factors for schizophrenia: between the diversity of aetiological models and personalised psychiatry
Selected risk factors for schizophrenia: between the diversity of aetiological models and personalised psychiatry Open
Schizofrenia należy do coraz poważniejszych problemów medycznych i społecznych. Pomimo postępu w farmakoterapii i innych formach terapii psychoz pozostaje ona zaburzeniem o chronicznym i degradującym przebiegu. Kilka dekad badań nad jej uw…