Amira Hussien
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View article: Computational Insights into Natural Antischistosomal Metabolites as SmHDAC8 Inhibitors: Molecular Docking, ADMET Profiling, and Molecular Dynamics Simulation
Computational Insights into Natural Antischistosomal Metabolites as SmHDAC8 Inhibitors: Molecular Docking, ADMET Profiling, and Molecular Dynamics Simulation Open
Schistosomiasis is a neglected tropical disease with a significant socioeconomic impact. It is caused by several species of blood trematodes from the genus Schistosoma, with S. mansoni being the most prevalent. Praziquantel (PZQ) is the on…
View article: Imaging of metastatic epidural spinal cord compression
Imaging of metastatic epidural spinal cord compression Open
Metastatic epidural spinal cord compression develops in 5–10% of patients with cancer and is becoming more common as advancement in cancer treatment prolongs survival in patients with cancer ( 1 – 3 ). It represents an oncological emergenc…
View article: Radiologic response of chemotherapy alone versus radiation and chemotherapy in the treatment of <scp>locally‐advanced</scp> or advanced thymic epithelial tumors
Radiologic response of chemotherapy alone versus radiation and chemotherapy in the treatment of <span>locally‐advanced</span> or advanced thymic epithelial tumors Open
Background Here, we investigated radiological responses following chemotherapy alone as compared to both radiation/chemotherapy (chemoRT) in patients with thymic epithelial tumors (TETs) who did not receive upfront surgery. Methods TETs tr…
View article: Fibrotic Lung Disease at CT Predicts Adverse Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement
Fibrotic Lung Disease at CT Predicts Adverse Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement Open
The presence of fibrosis on baseline CT scans was an independent predictor of adverse events after TAVR. In particular, fibrosis had improved predictive value in both patients without known CLD and patients without airway obstruction.Su…
View article: HIV Infection Is Independently Associated with Increased CT Scan Lung Density
HIV Infection Is Independently Associated with Increased CT Scan Lung Density Open
Non-infectious pulmonary complications are common among HIV-infected individuals and may be detected early by quantitative CT scan. The association of HIV disease markers with CT lung density measurement remains poorly understood.
View article: Longitudinal assessment of interstitial lung disease in single lung transplant recipients with scleroderma
Longitudinal assessment of interstitial lung disease in single lung transplant recipients with scleroderma Open
Objective To investigate the natural history of fibrotic lung disease in recipients of a single lung transplant for scleroderma-associated interstitial lung disease (ILD). Methods Global ILD (including ground glass, nodular opacities and f…
View article: Long-term treatment with human immunoglobulin for antisynthetase syndrome-associated interstitial lung disease
Long-term treatment with human immunoglobulin for antisynthetase syndrome-associated interstitial lung disease Open
View article: In Silico Screening and Analysis of SNPs in Human ABCB1 (MDR1) Gene
In Silico Screening and Analysis of SNPs in Human ABCB1 (MDR1) Gene Open
Background: ABCB1 (MDR1) is a transporter glycoprotein that has a major role in drug effluxes and resistance. Single nucleotide polymorphisms (SNPs) in ABCB1gene may affect protein expression, disease susceptibility and drug response, side…
View article: Added Value of Computer-aided CT Image Features for Early Lung Cancer Diagnosis with Small Pulmonary Nodules: A Matched Case-Control Study
Added Value of Computer-aided CT Image Features for Early Lung Cancer Diagnosis with Small Pulmonary Nodules: A Matched Case-Control Study Open
Purpose To test whether computer-aided diagnosis (CAD) approaches can increase the positive predictive value (PPV) and reduce the false-positive rate in lung cancer screening for small nodules compared with human reading by thoracic radiol…
View article: HIV Infection Is Independently Associated with Increased CT Scan Lung Density
HIV Infection Is Independently Associated with Increased CT Scan Lung Density Open