Amnah Mahroo
YOU?
Author Swipe
View article: New physiological insights using multi-TE ASL MRI measuring blood–brain barrier water exchange after caffeine intake
New physiological insights using multi-TE ASL MRI measuring blood–brain barrier water exchange after caffeine intake Open
View article: Noninvasive blood–brain barrier integrity mapping in patients with high‐grade glioma and metastasis by multi–echo time–encoded arterial spin labeling
Noninvasive blood–brain barrier integrity mapping in patients with high‐grade glioma and metastasis by multi–echo time–encoded arterial spin labeling Open
Purpose In brain tumors, disruption of the blood–brain barrier (BBB) indicates malignancy. Clinical assessment is qualitative; quantitative evaluation is feasible using the K 2 leakage parameter from dynamic susceptibility contrast MRI. Ho…
View article: Blood-brain barrier water permeability across the adult lifespan: A multi-echo ASL study
Blood-brain barrier water permeability across the adult lifespan: A multi-echo ASL study Open
An emerging biomarker of blood-brain barrier (BBB) permeability is the time of exchange (Tex) of water from the blood to tissue, as measured by multi-echo arterial spin labeling (ASL) MRI. This new non-invasive sequence, already tested in …
View article: Blood-Brain Barrier Water Exchange in Relation to Amyloid, Cognition and Cerebrovascular Burden
Blood-Brain Barrier Water Exchange in Relation to Amyloid, Cognition and Cerebrovascular Burden Open
View article: Measurement of blood–brain barrier water exchange rate using diffusion‐prepared and multi‐echo arterial spin labelling: Comparison of quantitative values and age dependence
Measurement of blood–brain barrier water exchange rate using diffusion‐prepared and multi‐echo arterial spin labelling: Comparison of quantitative values and age dependence Open
Water exchange rate (Kw) across the blood–brain barrier (BBB) is an important physiological parameter that may provide new insight into ageing and neurodegenerative disease. Recently, two non‐invasive arterial spin labelling (ASL) MRI meth…
View article: Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer’s disease (DEBBIE-AD): a prospective observational multicohort study protocol
Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer’s disease (DEBBIE-AD): a prospective observational multicohort study protocol Open
Introduction Loss of blood-brain barrier (BBB) integrity is hypothesised to be one of the earliest microvascular signs of Alzheimer’s disease (AD). Existing BBB integrity imaging methods involve contrast agents or ionising radiation, and p…
View article: Normal Blood-Brain Barrier Water Permeability Across the Lifespan: A Multi-Echo Asl Study
Normal Blood-Brain Barrier Water Permeability Across the Lifespan: A Multi-Echo Asl Study Open
View article: DEveloping BBB-ASL as non-Invasive Early biomarker of Alzheimer's Disease (DEBBIE-AD): Study design
DEveloping BBB-ASL as non-Invasive Early biomarker of Alzheimer's Disease (DEBBIE-AD): Study design Open
Introduction: Arterial spin labeling (ASL) MRI, a non-invasive technique for imaging perfusion, now allows studying BBB permeability. The DEveloping BBB-ASL as a non-Invasive Early biomarker of Alzheimer's Disease (DEBBIE-AD) multi-cohort …
View article: Blood‐brain barrier permeability measured with arterial spin labeling as potential cerebrovascular biomarker over the lifespan
Blood‐brain barrier permeability measured with arterial spin labeling as potential cerebrovascular biomarker over the lifespan Open
Background Blood‐brain barrier (BBB) dysfunction is considered a hallmark of Alzheimer’s disease (AD), making non‐invasive imaging of BBB with arterial spin labeling (ASL) MRI a potential imaging biomarker (BBB‐ASL). However, the normal BB…
View article: Blood‐brain barrier permeability measured with arterial spin labeling as potential cerebrovascular biomarker over the lifespan
Blood‐brain barrier permeability measured with arterial spin labeling as potential cerebrovascular biomarker over the lifespan Open
Background Blood‐brain barrier (BBB) dysfunction is considered a hallmark of Alzheimer’s disease (AD), making non‐invasive imaging of BBB with arterial spin labeling (ASL) MRI a potential imaging biomarker (BBB‐ASL). However, the normal BB…
View article: Subject-specific timing adaption in time-encoded arterial spin labeling imaging
Subject-specific timing adaption in time-encoded arterial spin labeling imaging Open
View article: Blood–Brain Barrier Permeability to Water Measured Using Multiple Echo Time Arterial Spin Labeling <scp>MRI</scp> in the Aging Human Brain
Blood–Brain Barrier Permeability to Water Measured Using Multiple Echo Time Arterial Spin Labeling <span>MRI</span> in the Aging Human Brain Open
Background The blood–brain barrier (BBB) plays a vital role in maintaining brain homeostasis, but the integrity of this barrier deteriorates slowly with aging. Noninvasive water exchange magnetic resonance imaging (MRI) methods may identif…
View article: Robust Multi-TE ASL-Based Blood–Brain Barrier Integrity Measurements
Robust Multi-TE ASL-Based Blood–Brain Barrier Integrity Measurements Open
Multiple echo-time arterial spin labelling (multi-TE ASL) offers estimation of blood–tissue exchange dynamics by probing the T2 relaxation of the labelled spins. In this study, we provide a recipe for robust assessment of exchange time (Te…
View article: Nanomedicine and cancer immunotherapy: focus on indoleamine 2,3-dioxygenase inhibitors
Nanomedicine and cancer immunotherapy: focus on indoleamine 2,3-dioxygenase inhibitors Open
Nanomedicine application in cancer immunotherapy is currently one of the most challenging areas in cancer therapeutic intervention. Innovative solutions have been provided by nanotechnology to deliver cytotoxic agents to the cancer cells p…