Amr K. Hassan
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View article: Comparative safety of cholinesterase inhibitors and memantine for dementia: a protocol for a network meta-analysis of randomized controlled trials
Comparative safety of cholinesterase inhibitors and memantine for dementia: a protocol for a network meta-analysis of randomized controlled trials Open
View article: GLP-1 receptor agonists in Parkinson’s disease: an updated comprehensive systematic review with meta-analysis
GLP-1 receptor agonists in Parkinson’s disease: an updated comprehensive systematic review with meta-analysis Open
View article: Secondary Macular Hole Closure With Sub-Tenon Triamcinolone Acetonide
Secondary Macular Hole Closure With Sub-Tenon Triamcinolone Acetonide Open
Purpose: To evaluate the efficacy and safety of sub-Tenon triamcinolone acetonide in the management of secondary full-thickness macular holes after vitreoretinal surgeries or traumatic injury. Methods: This case series includes 3 patients …
View article: Efficacy and safety of remote electrical neuromodulation in migraine: a comprehensive systematic review and meta-analysis
Efficacy and safety of remote electrical neuromodulation in migraine: a comprehensive systematic review and meta-analysis Open
View article: Comparative effectiveness of different types of female condoms: a systematic review and network meta-analysis
Comparative effectiveness of different types of female condoms: a systematic review and network meta-analysis Open
Background The female condom is a type of barrier contraception with a wide range of benefits. These benefits include significantly reducing the risk of sexually transmitted diseases and the number of unintentional pregnancies; however, th…
View article: Efficacy and safety of fecal microbiota transplantation in the management of parkinson’s disease: a systematic review
Efficacy and safety of fecal microbiota transplantation in the management of parkinson’s disease: a systematic review Open
FMT may relieve PD symptoms, but findings are inconsistent. Larger trials with standardized protocols are needed to determine its long-term efficacy and safety.
View article: Idebenone vs. rAAV2-ND4 gene therapy in the treatment of Leber’s hereditary optic neuropathy: An indirect comparison meta-analysis
Idebenone vs. rAAV2-ND4 gene therapy in the treatment of Leber’s hereditary optic neuropathy: An indirect comparison meta-analysis Open
To compare the outcomes between idebenone oral therapy and rAAV2-ND4 intravitreal injection in the treatment of Leber’s hereditary optic neuropathy. A systematic literature review was performed of publications from 1990 to 2023 in PubMed, …
View article: Large Language Models: Pioneering New Educational Frontiers in Childhood Myopia
Large Language Models: Pioneering New Educational Frontiers in Childhood Myopia Open
ChatGPT-4o (o1 Preview) demonstrates potential in producing accurate, good-quality, understandable PEMs, and in improving online PEMs on childhood myopia.
View article: Animal models for the evaluation of retinal stem cell therapies
Animal models for the evaluation of retinal stem cell therapies Open
Retinal degeneration (RD) diseases leading to severe vision loss can affect photoreceptors (PRs) that are responsible for phototransduction, or retinal pigmented epithelium (RPE) providing support for PRs. Human pluripotent stem cell (hPSC…
View article: Multimodal diagnostic tools and advanced data models for detection of prodromal Parkinson’s disease: a scoping review
Multimodal diagnostic tools and advanced data models for detection of prodromal Parkinson’s disease: a scoping review Open
Background Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. PD is diagnosed by a combination of motor symptoms including bradykine…
View article: Exploring the association between statins use or HMG-CoA reductase inhibition and migraine: a systematic review and meta-analysis
Exploring the association between statins use or HMG-CoA reductase inhibition and migraine: a systematic review and meta-analysis Open
Background Statins or 3‑hydroxy‑3‑methyl‑glutarylcoenzyme A (HMG‑CoA) reductase inhibitors are medications that act by reducing the cholesterol content of liver cells Moreover, statins have been found to improve endothelial function and re…
View article: Outcomes of the Paul Glaucoma Implant in Refractory Secondary Glaucoma
Outcomes of the Paul Glaucoma Implant in Refractory Secondary Glaucoma Open
The PGI demonstrated favorable efficacy and safety profiles in the management of medically uncontrolled secondary glaucomas.
View article: Anterior chamber and retropupillary iris-claw intar ocular lens fixation comparison of clinical outcomes: a systematic review
Anterior chamber and retropupillary iris-claw intar ocular lens fixation comparison of clinical outcomes: a systematic review Open
Background: In cataract surgery, optimal intraocular lens (IOL) placement is typically within the capsular bag. However, in the absence of sufficient capsular support, alternative techniques such as scleral-sutured IOLs, anterior chamber I…
View article: Acute myocardial infarction presenting as headache: a case report
Acute myocardial infarction presenting as headache: a case report Open
Background The diagnosis of acute myocardial infarction is straightforward when it presents with typical symptoms. However, some patients can be asymptomatic, and some can present with atypical symptoms. Case presentation We present a very…
View article: Purtscher’s and Purtscher-like retinopathy etiology, features, management, and outcomes: A summative systematic review of 168 cases
Purtscher’s and Purtscher-like retinopathy etiology, features, management, and outcomes: A summative systematic review of 168 cases Open
Background To describe Purtscher’s and Purtscher-like retinopathy clinical features, etiologies, management options, and visual outcomes. Methods Our protocol was registered on PROSPERO [registration number: CRD42023406843 ]. Seven online …
View article: Efficacy of Intravitreal rAAV2-ND4 Injection in Treated Versus Fellow Eyes with Leber’s Hereditary Optic Neuropathy: A Meta-Analysis
Efficacy of Intravitreal rAAV2-ND4 Injection in Treated Versus Fellow Eyes with Leber’s Hereditary Optic Neuropathy: A Meta-Analysis Open
To compare the outcomes of rAAV2-ND4 injection in treated versus fellow eyes with Leber's hereditary optic neuropathy (LHON). The protocol was pre-registered on PROSPERO (CRD42023441669). PubMed, Ovid MEDLINE, Cochrane CENTRAL, Google Scho…
View article: The characteristics of white dot syndromes following COVID-19 Vaccines: a systematic review
The characteristics of white dot syndromes following COVID-19 Vaccines: a systematic review Open
View article: Automated Category and Trend Analysis of Scientific Articles on Ophthalmology Using Large Language Models: Development and Usability Study
Automated Category and Trend Analysis of Scientific Articles on Ophthalmology Using Large Language Models: Development and Usability Study Open
Background In this paper, we present an automated method for article classification, leveraging the power of large language models (LLMs). Objective The aim of this study is to evaluate the applicability of various LLMs based on textual co…
View article: Continuous Wave Transscleral Cyclophotocoagulation and Endoscopic Cyclophotocoagulation in Childhood Glaucoma: A Meta-Analysis
Continuous Wave Transscleral Cyclophotocoagulation and Endoscopic Cyclophotocoagulation in Childhood Glaucoma: A Meta-Analysis Open
Précis: Transscleral cyclophotocoagulation (TS-CPC) and endoscopic cyclophotocoagulation (ECP) were effective in reducing intraocular pressure (IOP) and glaucoma medications in childhood glaucoma. Objective: To report the outcomes of conti…
View article: Automated Category and Trend Analysis of Scientific Articles on Ophthalmology Using Large Language Models: Development and Usability Study (Preprint)
Automated Category and Trend Analysis of Scientific Articles on Ophthalmology Using Large Language Models: Development and Usability Study (Preprint) Open
BACKGROUND In this paper, we present an automated method for article classification, leveraging the power of large language models (LLMs). OBJECTIVE The aim of this study is to evaluate the applicability of various LLMs based on textual…
View article: Using Large Language Models to Automate Category and Trend Analysis of Scientific Articles: An Application in Ophthalmology
Using Large Language Models to Automate Category and Trend Analysis of Scientific Articles: An Application in Ophthalmology Open
Purpose: In this paper, we present an automated method for article classification, leveraging the power of Large Language Models (LLM). The primary focus is on the field of ophthalmology, but the model is extendable to other fields. Method…
View article: Assessment of Retinal Nerve Fiber Layer Thickness Using Optical Coherence Tomography Before and After Ranibizumab Intravitreal Injection in Patients with Diabetic Macular Edema
Assessment of Retinal Nerve Fiber Layer Thickness Using Optical Coherence Tomography Before and After Ranibizumab Intravitreal Injection in Patients with Diabetic Macular Edema Open
View article: Sleep quality, stress level and COVID-19 in university students; the forgotten dimension
Sleep quality, stress level and COVID-19 in university students; the forgotten dimension Open
Introduction: COVID-19 is a novel pandemic that has had a profound impact on global physical and psychological health. We aimed to investigate the impact of COVID-19 on stress, sleep quality, and insomnia among South Valley University stud…
View article: Perceived Stress of Quarantine and Isolation During COVID-19 Pandemic: A Global Survey
Perceived Stress of Quarantine and Isolation During COVID-19 Pandemic: A Global Survey Open
Aims: Understanding of the perceived stress and coping strategies adopted by people is important for contemplating the consequences of a pandemic on mental health of people globally. In this study, we intended to assess the perceived stres…
View article: Outcome comparison between wavefront-guided and wavefront-optimized photorefractive keratectomy: A systematic review and meta-analysis
Outcome comparison between wavefront-guided and wavefront-optimized photorefractive keratectomy: A systematic review and meta-analysis Open
Photorefractive keratectomy (PRK) eye surgery is widely used for patients at risk for corneal ectasia to maintain an aspheric corneal shape. Wavefront-guided (WFG) ablation profile was designed to reduce pre-existing higher-order aberratio…