Amy E. Decker
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View article: Cancer genes disfavoring T cell immunity identified via integrated systems approach
Cancer genes disfavoring T cell immunity identified via integrated systems approach Open
Adoptive T cell therapies (ACT) have been curative for a limited number of cancer patients. The sensitization of cancer cells to T cell killing may expand the benefit of these therapies for more patients. To this end, we use a three-step a…
Physiological Demands of Common Occupational Tasks among Australian Police Officers: A Descriptive Analysis Open
Objectives The aim of this study was to investigate the physiological demands placed on Australian police officers carrying out common operational tasks. Methods Forty participants (n = 40) from an Australian police force (mean age = 33.58…
Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer Open
Tumor relapse is the leading cause of death in breast cancer, largely due to the fact that recurrent tumors are frequently resistant to chemotherapy. We previously reported that downregulation of the proapoptotic protein Par-4 promotes tum…
Physiological demands of law enforcement occupational tasks in Australian police officers Open
Research suggests that law enforcement is primarily a sedentary occupation. However, officers may have to respond rapidly to unpredictable situations and this can dramatically increase their physiological loads. The aim of this study was t…