Amy Eapen
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View article: Genotypes in the 17q12‐q21 asthma risk locus and early‐life viral wheezing illnesses
Genotypes in the 17q12‐q21 asthma risk locus and early‐life viral wheezing illnesses Open
View article: Immune pathways and perinatal environmental exposures contribute to epigenetic gestational age prediction and acceleration
Immune pathways and perinatal environmental exposures contribute to epigenetic gestational age prediction and acceleration Open
DNA methylation (DNAm), capturing biological gestational age (GA) and epigenetic gestational age acceleration (EGAA), can be modified by environmental exposures. The Asthma&Allergy array is a new DNAm array developed with content focused o…
View article: Phenotypes of Atopic Dermatitis and Development of Allergic Diseases
Phenotypes of Atopic Dermatitis and Development of Allergic Diseases Open
Importance Atopic dermatitis (AD) is the most common inflammatory disease in childhood, and children with AD are more likely to develop other allergic diseases, including food allergy, allergic rhinitis, and asthma. Objective To determine …
View article: Early childhood atopic phenotypes and the development of allergic respiratory disease
Early childhood atopic phenotypes and the development of allergic respiratory disease Open
View article: Early Childhood Atopic Phenotypes and the Development of Allergic Respiratory Disease
Early Childhood Atopic Phenotypes and the Development of Allergic Respiratory Disease Open
Early Childhood Atopic Phenotypes and the Development of Allergic Respiratory DiseaseTo the Editor,Pediatric atopic dermatitis (AD) is a chronic, pruritic, inflammatory skin disorder that affects up to 20% of children worldwide1. Often the…
View article: Longitudinal assessment of Allergic Outcomes and Atopic Dermatitis Phenotypes in The Children's Respiratory and Environmental Workgroup (CREW) Birth Cohort Consortium
Longitudinal assessment of Allergic Outcomes and Atopic Dermatitis Phenotypes in The Children's Respiratory and Environmental Workgroup (CREW) Birth Cohort Consortium Open
View article: Effect of prenatal dog exposure on eczema development in early and late childhood
Effect of prenatal dog exposure on eczema development in early and late childhood Open
View article: Race is a modifier between parental allergy and food allergy in offspring
Race is a modifier between parental allergy and food allergy in offspring Open
Figure S1 Figure S2 Figure S3 Table S1 Table S2 Table S3 Table S4 Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content…
View article: Race is a Modifier between Parental Allergy and Food Allergy in Offspring
Race is a Modifier between Parental Allergy and Food Allergy in Offspring Open
Race is a Modifier between Parental Allergy and Food Allergy in OffspringAmy A. Eapen, MD, MS*1, Erica Ridley MD*1, Alexandra R. Sitarik MS2, Christine Joseph PhD2, Christian Nageotte, MD1, Rana Misiak, MD1, Dennis Ownby MD3, Christine Joh…
View article: Epigenetic and transcriptional dysregulation in CD4+ T cells in patients with atopic dermatitis
Epigenetic and transcriptional dysregulation in CD4+ T cells in patients with atopic dermatitis Open
Atopic dermatitis (AD) is one of the most common skin disorders among children. Disease etiology involves genetic and environmental factors, with 29 independent AD risk loci enriched for risk allele-dependent gene expression in the skin an…
View article: Epigenetic and Transcriptional Dysregulation in CD4+ T cells of Patients with Atopic Dermatitis
Epigenetic and Transcriptional Dysregulation in CD4+ T cells of Patients with Atopic Dermatitis Open
Atopic dermatitis (AD) is one of the most common skin disorders in children. Disease etiology involves genetic and environmental factors, with the 29 independent AD risk loci enriched for risk allele-dependent gene expression in the skin a…
View article: Peanut oral immunotherapy in a pediatric allergy clinic: Patient factors associated with clinical outcomes
Peanut oral immunotherapy in a pediatric allergy clinic: Patient factors associated with clinical outcomes Open
Clinical peanut OIT has similar outcomes to research protocols. OIT can be successful in older children and those with high peanut-sIgE levels, though these factors affect outcomes. Clinical and laboratory criteria can guide successful tra…
View article: The Phenotype of the Food-Allergic Patient
The Phenotype of the Food-Allergic Patient Open
View article: Do Age and Baseline Peanut-specific IgE Levels Predict Oral Immunotherapy Outcomes?
Do Age and Baseline Peanut-specific IgE Levels Predict Oral Immunotherapy Outcomes? Open
View article: Replication and meta-analyses nominate numerous eosinophilic esophagitis risk genes
Replication and meta-analyses nominate numerous eosinophilic esophagitis risk genes Open
View article: Comprehensive Review of Steroid-Sensitive Nephrotic Syndrome Genetic Risk Loci and Transcriptional Regulation as a Possible Mechanistic Link to Disease Risk
Comprehensive Review of Steroid-Sensitive Nephrotic Syndrome Genetic Risk Loci and Transcriptional Regulation as a Possible Mechanistic Link to Disease Risk Open
SSNS is a complex disease, and immune dysregulation has been previously implicated as a potential underlying cause. This assessment of established SSNS risk loci and analysis of possible function implicates transcriptional dysregulation, a…
View article: Massively Parallel Reporter Assays (MPRAs) Identify Allelic Transcriptional Dysregulation in Atopic Dermatitis
Massively Parallel Reporter Assays (MPRAs) Identify Allelic Transcriptional Dysregulation in Atopic Dermatitis Open
View article: Oral immunotherapy for multiple foods in a pediatric allergy clinic setting
Oral immunotherapy for multiple foods in a pediatric allergy clinic setting Open
View article: Oral Immunotherapy for Multiple Foods
Oral Immunotherapy for Multiple Foods Open
View article: NFκB transcription factor binding is altered at many Atopic Dermatitis disease loci
NFκB transcription factor binding is altered at many Atopic Dermatitis disease loci Open
View article: Oral Food Challenge Failures Among Foods Eliminated to Treat Atopic Dermatitis
Oral Food Challenge Failures Among Foods Eliminated to Treat Atopic Dermatitis Open