Amy Kuceyeski
YOU?
Author Swipe
View article: Inferring intrinsic neural timescales using optimal control theory
Inferring intrinsic neural timescales using optimal control theory Open
The temporal evolution of whole-brain activity is contingent upon complex interactions within and between brain regions that are mediated by neurobiology and connectivity, respectively. Here, we provide a framework for studying these relat…
View article: Regularized CCA identifies sex-specific brain-behavior associations in adolescent psychopathology
Regularized CCA identifies sex-specific brain-behavior associations in adolescent psychopathology Open
View article: Socioemotional and Executive Control Mismatch in Adolescence and Risks for Initiating Drinking
Socioemotional and Executive Control Mismatch in Adolescence and Risks for Initiating Drinking Open
Importance Maturational imbalance between the expression of heightened socioemotional drivers and immature executive control creates a period of vulnerability to risk-taking behaviors during adolescence. Developmental imbalance of the brai…
View article: Cocaine use disorder is associated with lower brain state transition energy particularly in higher order and excitatory networks
Cocaine use disorder is associated with lower brain state transition energy particularly in higher order and excitatory networks Open
Cocaine use disorder (CUD) detrimentally impacts personal health, social relationships, and economic opportunity. Here, we assess CUD-associated shifts in brain dynamics using Network Control Theory and examine how they align with previous…
View article: Statistical variability in comparing accuracy of neuroimaging based classification models via cross validation
Statistical variability in comparing accuracy of neuroimaging based classification models via cross validation Open
View article: Psilocybin Prolongs the Neurovascular Coupling Response in Mouse Visual Cortex
Psilocybin Prolongs the Neurovascular Coupling Response in Mouse Visual Cortex Open
Psilocybin has profound therapeutic potential for various mental health disorders, but its mechanisms of action are unknown. Functional MRI studies have reported the effects of psilocybin on brain activity and connectivity; however, these …
View article: View, engage, predict: enhancing brain-behavior mapping with naturalistic movie-watching fMRI
View, engage, predict: enhancing brain-behavior mapping with naturalistic movie-watching fMRI Open
Most brain-behavior mapping studies rely on resting-state functional connectivity (FC), but this approach has known accuracy limits and can be outperformed by movie-watching FC. Here, we present a novel deep neural network framework to pre…
View article: Identification of Brain Circuits that Mediate Improvements in Executive Function in Moderate to Severe Traumatic Brain Injury Patients Treated with Deep Brain Stimulation (DBS)
Identification of Brain Circuits that Mediate Improvements in Executive Function in Moderate to Severe Traumatic Brain Injury Patients Treated with Deep Brain Stimulation (DBS) Open
View article: Disrupted Energy Landscape in Individuals with Mild Cognitive Impairment: Insights from Network Control Theory
Disrupted Energy Landscape in Individuals with Mild Cognitive Impairment: Insights from Network Control Theory Open
Introduction Patients with mild cognitive impairment (MCI) have shown disruptions in both brain structure and function, often studied separately. However, understanding the relationship between brain structure and function can provide valu…
View article: Krakencoder: a unified brain connectome translation and fusion tool
Krakencoder: a unified brain connectome translation and fusion tool Open
View article: Inferring macroscopic intrinsic neural timescales using optimal control theory
Inferring macroscopic intrinsic neural timescales using optimal control theory Open
The temporal evolution of brain activity relies on complex interactions within and between brain regions that are mediated by neurobiology and connectivity. To understand these interactions, many large-scale efforts have measured structura…
View article: Network control energy reductions under DMT relate to serotonin receptors, signal diversity, and subjective experience
Network control energy reductions under DMT relate to serotonin receptors, signal diversity, and subjective experience Open
Psychedelics offer a profound window into the human brain through their robust effects on perception, subjective experience, and brain activity patterns. The serotonergic psychedelic N,N-dimethyltryptamine (DMT) induces a profoundly immers…
View article: Longitudinal multimodal neuroimaging after traumatic brain injury
Longitudinal multimodal neuroimaging after traumatic brain injury Open
Traumatic brain injury is a major cause of long-term cognitive impairment, yet the mechanisms underlying recovery remain poorly understood. Neuroimaging methods such as diffusion MRI, functional MRI, and positron emission tomography (PET) …
View article: Predicting cognition using estimated structural and functional connectivity networks and artificial intelligence in multiple sclerosis
Predicting cognition using estimated structural and functional connectivity networks and artificial intelligence in multiple sclerosis Open
Our prior work demonstrated that estimated structural and functional connectomes (eSC and eFC) generated using multiple sclerosis (MS) lesion masks and artificial intelligence (AI) models can predict disability as effectively as SC and FC …
View article: Predicting cognition using estimated structural and functional connectivity networks and artificial intelligence in multiple sclerosis
Predicting cognition using estimated structural and functional connectivity networks and artificial intelligence in multiple sclerosis Open
Background Our prior work demonstrated that estimated structural and functional connectomes (eSC and eFC) generated using multiple sclerosis (MS) lesion masks and artificial intelligence (AI) models can predict disability as effectively as…
View article: TSPO-PET Reveals Higher Inflammation in White Matter Disrupted by Paramagnetic Rim Lesions in Multiple Sclerosis
TSPO-PET Reveals Higher Inflammation in White Matter Disrupted by Paramagnetic Rim Lesions in Multiple Sclerosis Open
Objective To explore whether the inflammatory activity is higher in white matter (WM) tracts disrupted by paramagnetic rim lesions (PRLs) and if inflammation in PRL-disrupted WM tracts is associated with disability in people with multiple …
View article: Brain Activity Dynamics after Traumatic Brain Injury Indicate Increased State Transition Energy and Preference of Lower Order States
Brain Activity Dynamics after Traumatic Brain Injury Indicate Increased State Transition Energy and Preference of Lower Order States Open
View article: Coupling of Event-Related Potential and Pupil Dilation as a Compensatory Marker of Executive Attention in Traumatic Brain Injury
Coupling of Event-Related Potential and Pupil Dilation as a Compensatory Marker of Executive Attention in Traumatic Brain Injury Open
Traumatic brain injury (TBI) impairs attention and executive function, often through disrupted coordination between cognitive and autonomic systems. While electroencephalography (EEG) and pupillometry are widely used to assess neural and a…
View article: Brain activity dynamics after traumatic brain injury indicate increased state transition energy and preference of lower order states
Brain activity dynamics after traumatic brain injury indicate increased state transition energy and preference of lower order states Open
View article: Direct perception of affective valence from vision
Direct perception of affective valence from vision Open
Subjective feelings are thought to arise from conceptual and bodily states. We examine whether the valence of feelings may also be decoded directly from objective ecological statistics of the visual environment. We train a visual valence (…
View article: Utilizing structural MRI and unsupervised clustering to differentiate schizophrenia and Alzheimer's disease in late-onset psychosis
Utilizing structural MRI and unsupervised clustering to differentiate schizophrenia and Alzheimer's disease in late-onset psychosis Open
View article: Decreased entropy of functional MRI signals in individuals with mild cognitive impairment compared to cognitively normal controls
Decreased entropy of functional MRI signals in individuals with mild cognitive impairment compared to cognitively normal controls Open
Background Mild cognitive impairment (MCI) is a clinical cognitive deficit that is not severe enough to meet the threshold for Alzheimer's Disease (AD); however, MCI patients have an increased risk of developing AD. Therefore, a diagnosis …
View article: Sex-specific differences in brain activity dynamics of youth with a family history of substance use disorder
Sex-specific differences in brain activity dynamics of youth with a family history of substance use disorder Open
An individual’s risk of substance use disorder (SUD) is shaped by a complex interplay of potent biosocial factors. Current neurodevelopmental models posit vulnerability to SUD in youth is due to an overreactive reward system and reduced in…
View article: The Transition From Homogeneous to Heterogeneous Machine Learning in Neuropsychiatric Research
The Transition From Homogeneous to Heterogeneous Machine Learning in Neuropsychiatric Research Open
Despite the advantage of neuroimaging-based machine learning (ML) models as pivotal tools for investigating brain-behavior relationships in neuropsychiatric studies, these data-driven predictive approaches have yet to yield substantial, cl…
View article: Predicting Task Activation Maps from Resting-State Functional Connectivity using Deep Learning
Predicting Task Activation Maps from Resting-State Functional Connectivity using Deep Learning Open
Deep learning has been proven effective in predicting brain activation patterns from resting-state features. In this work, using resting state and task fMRI data from the Human Connectome Project (HCP), we replicate the state-of-the-art de…
View article: Sex-specific differences in brain activity dynamics of youth with a family history of substance use disorder
Sex-specific differences in brain activity dynamics of youth with a family history of substance use disorder Open
An individual’s risk of substance use disorder (SUD) is shaped by a complex interplay of potent biosocial factors. Current neurodevelopmental models posit vulnerability to SUD in youth is due to an overreactive reward system and reduced in…
View article: Contributions of network structure, chemoarchitecture and diagnostic categories to transitions between cognitive topographies
Contributions of network structure, chemoarchitecture and diagnostic categories to transitions between cognitive topographies Open
The mechanisms linking the brain’s network structure to cognitively relevant activation patterns remain largely unknown. Here, by leveraging principles of network control, we show how the architecture of the human connectome shapes transit…
View article: Release the Krakencoder: A unified brain connectome translation and fusion tool
Release the Krakencoder: A unified brain connectome translation and fusion tool Open
Brain connectivity can be estimated in many ways, depending on modality and processing strategy. Here we present the Krakencoder, a joint connectome mapping tool that simultaneously, bidirectionally translates between structural (SC) and f…
View article: Predicting Language Function Post-Stroke: A Model-Based Structural Connectivity Approach
Predicting Language Function Post-Stroke: A Model-Based Structural Connectivity Approach Open
Background The prediction of post-stroke language function is essential for the development of individualized treatment plans based on the personal recovery potential of aphasic stroke patients. Objective To establish a framework for integ…
View article: Point of View on Outcome Prediction Models in Post-Stroke Motor Recovery
Point of View on Outcome Prediction Models in Post-Stroke Motor Recovery Open
Stroke is a leading cause of disability worldwide which can cause significant and persistent upper limb (UL) impairment. It is difficult to predict UL motor recovery after stroke and to forecast the expected outcomes of rehabilitation inte…