Amy Levál
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View article: Overall Survival and Treatment Patterns Among Patients With Warm Autoimmune Hemolytic Anemia in Sweden: A Nationwide Population‐based Study
Overall Survival and Treatment Patterns Among Patients With Warm Autoimmune Hemolytic Anemia in Sweden: A Nationwide Population‐based Study Open
Objectives Warm autoimmune hemolytic anemia (wAIHA) is a rare autoantibody‐mediated disorder, and first‐line treatment primarily relies on corticosteroids. This study assessed overall survival (OS) and treatment patterns of wAIHA in Sweden…
View article: Determinants and Outcomes of Suicidal Behavior Among Patients With Major Depressive Disorder
Determinants and Outcomes of Suicidal Behavior Among Patients With Major Depressive Disorder Open
Importance Major depressive disorder (MDD) is an important risk factor of suicidal behavior, but the added burden of suicidal behavior and MDD on the patient and societal level, including all-cause mortality, is not well studied. Also, the…
View article: Melatonin use and the risk of self‐harm and unintentional injuries in youths with and without psychiatric disorders
Melatonin use and the risk of self‐harm and unintentional injuries in youths with and without psychiatric disorders Open
Background Sleep disorders in youth have been associated with increased risks of injury, including suicidal behavior. This study investigated whether melatonin, which is the most common medication for sleep disturbances in youth in Sweden,…
View article: Association of Treatment-Resistant Depression With Patient Outcomes and Health Care Resource Utilization in a Population-Wide Study
Association of Treatment-Resistant Depression With Patient Outcomes and Health Care Resource Utilization in a Population-Wide Study Open
Importance The totality of the societal and individual impact of treatment-resistant depression (TRD) is unknown, as is the potential to prognosticate TRD. The generalizability of many observational studies on TRD is limited. Objective To …
View article: Cardiovascular, bone, and metabolic health in men with castrate-resistant prostate cancer treated with androgen deprivation: a matched cohort study
Cardiovascular, bone, and metabolic health in men with castrate-resistant prostate cancer treated with androgen deprivation: a matched cohort study Open
In this cohort, the incidence of CVD was significantly higher among men with CRPC compared to healthy controls. Despite having this end-stage disease this finding proves that clinicians must recognize this late effect in men diagnosed with…
View article: Clinical and societal burden of incident major depressive disorder: A population‐wide cohort study in Stockholm
Clinical and societal burden of incident major depressive disorder: A population‐wide cohort study in Stockholm Open
Objective Major depressive disorder (MDD) is a highly prevalent condition and a significant contributor to global disability. The vast majority of MDD is handled by primary care, but most real‐life studies on MDD only include data from sec…
View article: Cardiovascular, bone, and metabolic health in men with castrate-resistant prostate cancer treated with androgen deprivation: a matched cohort study
Cardiovascular, bone, and metabolic health in men with castrate-resistant prostate cancer treated with androgen deprivation: a matched cohort study Open
Descriptive data on late effects associated with castrate-resistant prostate cancer (CRPC) are sparse. We aimed to define the timing and incidence of cardiovascular disease (CVD), fractures, and diabetes in a patient population with CRPC. …
View article: Association of severe childhood infections with depression and intentional self-harm in adolescents and young adults
Association of severe childhood infections with depression and intentional self-harm in adolescents and young adults Open
Early-life infections have been linked with subsequent depression and self-harm. Examination of specific groups of infections and the role of familial factors may elucidate this observed relationship. We addressed these considerations in o…
View article: Real world treatment utilization patterns in patients with castration-resistant prostate cancer
Real world treatment utilization patterns in patients with castration-resistant prostate cancer Open
Despite treatment availability, in this large real-world cohort we found treatment utilization to remain low.
View article: Overview of CAPICE—Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe—an EU Marie Skłodowska-Curie International Training Network
Overview of CAPICE—Childhood and Adolescence Psychopathology: unravelling the complex etiology by a large Interdisciplinary Collaboration in Europe—an EU Marie Skłodowska-Curie International Training Network Open
The Roadmap for Mental Health and Wellbeing Research in Europe (ROAMER) identified child and adolescent mental illness as a priority area for research. CAPICE (Childhood and Adolescence Psychopathology: unravelling the complex etiology by …
View article: Association of Youth Depression With Subsequent Somatic Diseases and Premature Death
Association of Youth Depression With Subsequent Somatic Diseases and Premature Death Open
In this Swedish population cohort study, patients with depression diagnosed during their youth appeared to have increased risks for many somatic diseases as well as for mortality, even after controlling for other psychiatric disorders. The…
View article: PD10-06 REAL-WORLD TREATMENT PATTERNS IN PATIENTS WITH CASTRATION-RESISTANT PROSTATE CANCER
PD10-06 REAL-WORLD TREATMENT PATTERNS IN PATIENTS WITH CASTRATION-RESISTANT PROSTATE CANCER Open
You have accessJournal of UrologyProstate Cancer: Advanced (including Drug Therapy) I (PD10)1 Apr 2020PD10-06 REAL-WORLD TREATMENT PATTERNS IN PATIENTS WITH CASTRATION-RESISTANT PROSTATE CANCER Hari T. Vigneswaran*, Anna Warnqvist, Therese…
View article: Survival in patients diagnosed with castration-resistant prostate cancer: a population-based observational study in Sweden
Survival in patients diagnosed with castration-resistant prostate cancer: a population-based observational study in Sweden Open
Background: This study investigated prostate cancer (PC)-specific survival and overall survival (OS) in a population-based castration-resistant PC (CRPC) cohort.Methods: Data from Stockholm Prostate-Specific Antigen (PSA) and Biopsy Regist…
View article: Observational evidence from patients diagnosed with chronic lymphocytic leukaemia (CLL) in Finland between 2005‐2015 show improved survival over time
Observational evidence from patients diagnosed with chronic lymphocytic leukaemia (CLL) in Finland between 2005‐2015 show improved survival over time Open
Objectives We aimed to describe treatment patterns of chronic lymphocytic leukaemia (CLL) patients in routine practice settings, compare overall survival and time‐to‐next‐treatment among patients treated in different time periods (2005‐200…
View article: Real-world treatment outcomes in multiple myeloma: Multicenter registry results from Finland 2009-2013
Real-world treatment outcomes in multiple myeloma: Multicenter registry results from Finland 2009-2013 Open
The adoption of novel treatments in MM in Finland has had substantial impact on patient outcomes. Given the reality of complex treatment combinations for MM and relatively low patient numbers, assessing individual treatment effectiveness w…
View article: Burden for Parents of Patients With Schizophrenia—A Nationwide Comparative Study of Parents of Offspring With Rheumatoid Arthritis, Multiple Sclerosis, Epilepsy, and Healthy Controls
Burden for Parents of Patients With Schizophrenia—A Nationwide Comparative Study of Parents of Offspring With Rheumatoid Arthritis, Multiple Sclerosis, Epilepsy, and Healthy Controls Open
Parents of patients with schizophrenia have a considerably higher risk of psychiatric health care and social welfare benefit receipt than other parents. Psychiatric health care use worsens over time and with increasing disease severity of …
View article: Antipsychotics and mortality in a nationwide cohort of 29,823 patients with schizophrenia
Antipsychotics and mortality in a nationwide cohort of 29,823 patients with schizophrenia Open
Among patients with schizophrenia, LAI use is associated with an approximately 30% lower risk of death compared with oral agents. SG LAIs and oral aripiprazole are associated with the lowest mortality.
View article: Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29 823 Patients With Schizophrenia
Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29 823 Patients With Schizophrenia Open
Clozapine and long-acting injectable antipsychotic medications were the pharmacologic treatments with the highest rates of prevention of relapse in schizophrenia. The risk of rehospitalization is about 20% to 30% lower during long-acting i…
View article: HIV drug therapy duration; a Swedish real world nationwide cohort study on InfCareHIV 2009-2014
HIV drug therapy duration; a Swedish real world nationwide cohort study on InfCareHIV 2009-2014 Open
Treatment durability is dependent on several factors among others patient characteristics and ART guidelines. The choice of 3rd agent has a strong impact and significant differences between different drugs on treatment duration exist.
View article: Real-time real-world analysis of seasonal influenza vaccine effectiveness: method development and assessment of a population-based cohort in Stockholm County, Sweden, seasons 2011/12 to 2014/15
Real-time real-world analysis of seasonal influenza vaccine effectiveness: method development and assessment of a population-based cohort in Stockholm County, Sweden, seasons 2011/12 to 2014/15 Open
Real-world estimates of seasonal influenza vaccine effectiveness (VE) are important for early detection of vaccine failure. We developed a method for evaluating real-time in-season vaccine effectiveness (IVE) and overall seasonal VE. In a …
View article: Gonorrhoea Diagnostic and Treatment Uncertainties: Risk Factors for Culture Negative Confirmation after Positive Nucleic Acid Amplification Tests
Gonorrhoea Diagnostic and Treatment Uncertainties: Risk Factors for Culture Negative Confirmation after Positive Nucleic Acid Amplification Tests Open
Gonorrhoea incidence has increased substantially in Stockholm during the past years. These increases have coincided with changes in testing practice from solely culture-based to nucleic acid amplification tests (NAAT). Gonorrhoea NAAT is i…