Amy Ming‐Fang Yen
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View article: Changhua Integrated Program to Stop HCV Infection (CHIPS–C): A county-wide model for integrated HCV elimination in Taiwan
Changhua Integrated Program to Stop HCV Infection (CHIPS–C): A county-wide model for integrated HCV elimination in Taiwan Open
The CHIPS-C program demonstrated that integrating HCV elimination within diverse communicable and noncommunicable disease programs can effectively accelerate progress toward elimination goals. This locally led, collaborative, and multi-cha…
View article: Artificial intelligence for precision viral surveillance of emerging infectious disease (EID): Data-driven digital twin metaverse-envisioned study
Artificial intelligence for precision viral surveillance of emerging infectious disease (EID): Data-driven digital twin metaverse-envisioned study Open
This Ct-guided, data-driven digital twin model demonstrates a novel approach to EID containment, highlighting the potential of the Metaverse as a convergence of physical and cyber domains. Our findings illustrate the applicability and scal…
View article: Personalized risk score for post‐COVID‐19 condition: Bayesian directed acyclic graphic approach
Personalized risk score for post‐COVID‐19 condition: Bayesian directed acyclic graphic approach Open
Post‐COVID‐19 condition (PCC) has gained traction currently in the post‐pandemic era. To address this, we utilized a Bayesian directed acyclic graphic (DAG) model to develop a personalized composite risk score (CRS) for PCC, based on the t…
View article: Quantifying Genetic and Environmental Factors Accounting for Multistage Progression of Precancerous Lesions and Oral Cancer: Applications to Risk-Guided Prevention
Quantifying Genetic and Environmental Factors Accounting for Multistage Progression of Precancerous Lesions and Oral Cancer: Applications to Risk-Guided Prevention Open
Background: Oral squamous cell carcinoma (OSCC) is a multifactorial and multistage disease influenced by both genetic susceptibility and environmental risk factors. However, conventional oral cancer preventions are often based on environme…
View article: Changes in risk habits and influencing factors in the Taiwan oral cancer screening program
Changes in risk habits and influencing factors in the Taiwan oral cancer screening program Open
This study examines changes in oral risk habits and identifies factors influencing these changes among participants in a population-based oral cancer screening program to support effective public health interventions. The study included 2,…
View article: Changes in oral risk habits and influencing factors among participants in an oral cancer screening program
Changes in oral risk habits and influencing factors among participants in an oral cancer screening program Open
This study examines changes in oral risk habits and identifies factors influencing these changes among participants in a population-based oral cancer screening program to support effective public health interventions. The study included 2,…
View article: Behavior Changes for Smokers and Betel Quid Chewers Participating in the Organized Oral Mucosal Screening Between 2010 and 2021 in Taiwan
Behavior Changes for Smokers and Betel Quid Chewers Participating in the Organized Oral Mucosal Screening Between 2010 and 2021 in Taiwan Open
Objective: To investigate the likelihood of smoking and betel quid chewing behavior changes, as well as the associated factors, among subjects in a nationwide oral cancer screening program in Taiwan, where oral cancer is the fourth leading…
View article: Behavior Changes for Smokers and Betel Quid Chewers Participating in the Organized Oral Mucosal Screening between 2010 and 2021 in Taiwan
Behavior Changes for Smokers and Betel Quid Chewers Participating in the Organized Oral Mucosal Screening between 2010 and 2021 in Taiwan Open
Objective: To investigate the likelihood of smoking and betel quid chewing behavior changes, as well as the associated factors, among subjects in a nationwide oral cancer screening program in Taiwan, where oral cancer is the fourth leading…
View article: Artificial Intelligence for Precision Viral Surveillance of Emerging Infection Disease (EID): The Metaverse-envisioned Study (Preprint)
Artificial Intelligence for Precision Viral Surveillance of Emerging Infection Disease (EID): The Metaverse-envisioned Study (Preprint) Open
BACKGROUND Precision containment measures guided by dynamic viral shedding are essential for effective control of emerging infectious diseases (EID) though the methodology is complex. The advent of metaverse applications in healthcare int…
View article: Risk Factors of Hepatitis Associated With Time to Adopting a New Cancer Screening Model Under Diffusion of Innovation Theory—A 10‐Year Cohort Study in Taiwan
Risk Factors of Hepatitis Associated With Time to Adopting a New Cancer Screening Model Under Diffusion of Innovation Theory—A 10‐Year Cohort Study in Taiwan Open
Background Hepatitis is a serious global health issue. To reduce mortality, early screening for liver disease has been recommended in community health policies, particularly for asymptomatic individuals. Aim This study explored the link be…
View article: Breast cancer incidence in mobile screening vs. in-hospital screening programmes based on 6 313 607 mammograms in 2 387 756 women in Taiwan
Breast cancer incidence in mobile screening vs. in-hospital screening programmes based on 6 313 607 mammograms in 2 387 756 women in Taiwan Open
BACKGROUND: Since 2010, Taiwan has conducted a population-based breast cancer screening programme that includes mobile units to improve the screening rate. This study aimed to compare the results of mobile breast cancer screening units wit…
View article: Metaverse-based Digital Twin Model for Monitoring Emerging Infection Using Dynamic Cycle Threshold Values (Preprint)
Metaverse-based Digital Twin Model for Monitoring Emerging Infection Using Dynamic Cycle Threshold Values (Preprint) Open
BACKGROUND Leveraging the metaverse concept to stop the spread of the emerging infectious disease offers novel insights into immersive experiences of precision contact tracing, isolation, and quarantine guided by dynamic viral shedding. …
View article: Precision Colorectal Cancer Fecal Immunological Test Screening With Fecal-Hemoglobin-Concentration–Guided Interscreening Intervals
Precision Colorectal Cancer Fecal Immunological Test Screening With Fecal-Hemoglobin-Concentration–Guided Interscreening Intervals Open
Importance Given a gradient relationship between fecal hemoglobin (f-Hb) concentration and colorectal neoplasia demonstrated previously, using f-Hb–guided interscreening interval has increasingly gained attention in population-based fecal …
View article: New insights into three trajectories of omicron-related all-cause death reduced by COVID-19 booster vaccination
New insights into three trajectories of omicron-related all-cause death reduced by COVID-19 booster vaccination Open
Our competing risk analysis is effective for monitoring all-cause death trajectories amidst various Omicron infections. It provides insights into the impact of booster vaccines, especially bivalent ones, and highlights the consequences of …
View article: Performance measures of 8,169,869 examinations in the National Breast Cancer Screening Program in Taiwan, 2004–2020
Performance measures of 8,169,869 examinations in the National Breast Cancer Screening Program in Taiwan, 2004–2020 Open
Background The benefits of mammographic screening have been shown to include a decrease in mortality due to breast cancer. Taiwan’s Breast Cancer Screening Program is a national screening program that has offered biennial mammographic brea…
View article: Kinetics of Viral Shedding for Outbreak Surveillance of Emerging Infectious Diseases: Modeling Approach to SARS-CoV-2 Alpha and Omicron Infection (Preprint)
Kinetics of Viral Shedding for Outbreak Surveillance of Emerging Infectious Diseases: Modeling Approach to SARS-CoV-2 Alpha and Omicron Infection (Preprint) Open
BACKGROUND Previous studies have highlighted the importance of viral shedding using cycle threshold (Ct) values obtained via reverse transcription polymerase chain reaction to understand the epidemic trajectories of SARS-CoV-2 infections.…
View article: Planning, implementing, and evaluating Hepatitis C virus elimination via collaborative community-based care cascade: age–period–cohort model for estimating demand from antecedent anti-HCV survey
Planning, implementing, and evaluating Hepatitis C virus elimination via collaborative community-based care cascade: age–period–cohort model for estimating demand from antecedent anti-HCV survey Open
Background Estimating the demand for HCV care cascade plays an important role in planning, monitoring, and assessing the performance of introducing a new community-based hepatitis C virus (HCV) elimination program but such an analytic and …
View article: Assessing Excess Mortality of Baby Boomers from the COVID-19 Pandemic: Taiwan Naïve Omicron Infection Study
Assessing Excess Mortality of Baby Boomers from the COVID-19 Pandemic: Taiwan Naïve Omicron Infection Study Open
Background: Asia's elderly Baby Boomer demographic (born between 1946 and 1964) faced a huge problem during the COVID-19 pandemic due to increased all-cause mortality. We aimed to provide a unique Taiwan situation regarding the impact of B…
View article: Planning, Implementing, and Evaluating Hepatitis C Virus Elimination via Collaborative Community-based Care Cascade: Age-period-cohort Model for Estimating Demand from Antecedent Anti-HCV Survey
Planning, Implementing, and Evaluating Hepatitis C Virus Elimination via Collaborative Community-based Care Cascade: Age-period-cohort Model for Estimating Demand from Antecedent Anti-HCV Survey Open
Background Estimating the demand for HCV care cascade plays an important role in planning, monitoring, and assessing the performance of introducing a new community-based hepatitis C virus (HCV) elimination program but such an analytic and …
View article: Beneficial effect of repeated participation in breast cancer screening upon survival
Beneficial effect of repeated participation in breast cancer screening upon survival Open
Objectives The benefit of mammography screening in reducing population mortality from breast cancer is well established. In this paper, we estimate the effect of repeated participation at scheduled screens on case survival. Methods We anal…
View article: Quantifying the Effects of Viral Load on Multistate COVID-19 Infection and Progression of Alpha and Omicron VOCs: A Bayesian Competing Markov Exponential Regression Model
Quantifying the Effects of Viral Load on Multistate COVID-19 Infection and Progression of Alpha and Omicron VOCs: A Bayesian Competing Markov Exponential Regression Model Open
We used a Bayesian competing four-state Markov model to explore how viral shedding in terms of cycle threshold (Ct) value makes relative contribution between persistent and non-persistent asymptomatic mode, and whether it affects the subse…
View article: Double‐contrast barium enema is no longer justified as a backup examination for colonoscopy in the population screening program: Population study in an organized fecal immunochemical test‐based screening program
Double‐contrast barium enema is no longer justified as a backup examination for colonoscopy in the population screening program: Population study in an organized fecal immunochemical test‐based screening program Open
Background and Aim Currently, some countries still acknowledge double‐contrast barium enema (DCBE) as a backup confirmatory examination when colonoscopy is not feasible or incomplete in colorectal cancer (CRC) screening programs. This stud…
View article: Data from Demand for Colonoscopy in Colorectal Cancer Screening Using a Quantitative Fecal Immunochemical Test and Age/Sex-Specific Thresholds for Test Positivity
Data from Demand for Colonoscopy in Colorectal Cancer Screening Using a Quantitative Fecal Immunochemical Test and Age/Sex-Specific Thresholds for Test Positivity Open
Background: Despite age and sex differences in fecal hemoglobin (f-Hb) concentrations, most fecal immunochemical test (FIT) screening programs use population-average cut-points for test positivity. The impact of age/sex-specific threshold …
View article: Data from Demand for Colonoscopy in Colorectal Cancer Screening Using a Quantitative Fecal Immunochemical Test and Age/Sex-Specific Thresholds for Test Positivity
Data from Demand for Colonoscopy in Colorectal Cancer Screening Using a Quantitative Fecal Immunochemical Test and Age/Sex-Specific Thresholds for Test Positivity Open
Background: Despite age and sex differences in fecal hemoglobin (f-Hb) concentrations, most fecal immunochemical test (FIT) screening programs use population-average cut-points for test positivity. The impact of age/sex-specific threshold …