Explanipedia

Cross-Cultural Consortium on Irritability (C3I): An International Network for Research on Cultural Similarities and Differences in Irritability Open

Wan‐Ling Tseng, Nellia Bellaert, Tami D. Benton, Melissa A. Brotman, Spencer C. Evans , et al. · 2025

Longitudinal Change in Adolescent Depression and Anxiety Symptoms from before to during the COVID‐19 Pandemic Open

Marjolein E.A. Barendse, Jessica Flannery, Caitlin Cavanagh, Melissa Aristizabal, Stephen P. Becker , et al. · 2025

This study aimed to examine changes in depression and anxiety symptoms from before to during the first 6 months of the COVID-19 pandemic in a sample of 1,339 adolescents (9-18 years old, 59% female) from three countries. We also examined i…

Preference for digital media use, biobehavioral attention bias, and anxiety symptoms in adolescents Open

Sarah Myruski, Jennifer de Rutte, Abigail Findley, Amy Krain Roy, Tracy A. Dennis-Tiwary · 2024

Adolescence is a critical developmental period of biological and social change during which 1 in 3 youth experience significant anxiety symptoms. The social-emotional lives of the majority of adolescents are largely conducted via digital m…

Irritability in Youths: A Critical Integrative Review Open

Ellen Leibenluft, Laura E. Allen, Robert R. Althoff, Melissa A. Brotman, Jeffrey D. Burke , et al. · 2024

Irritability, defined as proneness to anger that may impair an individual's functioning, is common in youths. There has been a recent upsurge in relevant research. The authors combine systematic and narrative review approaches to integrate…

Novel Assessment of the Impact of Irritability on Physiological and Psychological Frustration Responses in Adolescents Open

Erica Ferrara, Hyunjung Lee, Jill Stadterman, Melanie R. Somekh, Emily Hirsch , et al. · 2024

Results provide support for unique associations between adolescent irritability and anger during, and in anticipation of, frustrating social interactions. Such findings lay a foundation for future work aimed at informing physiological mode…

An investigation of the neural basis of anger attributions in irritable youth. Open

Margaret S. Benda, Mariah DeSerisy, Cara F. Levitch, Amy Krain Roy · 2023

Neurocognitive models of pediatric irritability suggest a prominent role of anger; however, few studies have investigated anger-related biases and their neural correlates. Resting state functional connectivity (rsFC) of the amygdala was ex…

Irritability in Youth: A Critical Integrative Review Open

Ellen Leibenluft, Laura B. Allen, Robert R. Althoff, Melissa A. Brotman, Jeffrey D. Burke , et al. · 2023

Irritability, defined as proneness to anger that may reach an impairing extent, is common in youth. There has been a recent upsurge in relevant research. We combine systematic and narrative review approaches to integrate the latest clinica…

Characterizing the spectrum of irritability in preadolescence: Dimensional and pragmatic applications Open

Tasmia Alam, Nathan Kirk, Emily Hirsch, Margaret J. Briggs‐Gowan, Lauren S. Wakschlag , et al. · 2023

Objectives Characterize the dimensional spectrum of preadolescent (PA) irritability, a robust transdiagnostic vulnerability marker, using the youth version of the Multidimensional Assessment Profiles Temper Loss (MAPS‐TL‐Youth) scale inclu…

Developmentally specified characterization of the irritability spectrum at early school age: Implications for pragmatic mental health screening Open

Emily Hirsch, Tasmia Alam, Nathan Kirk, Katherine B. Bevans, Margaret J. Briggs‐Gowan , et al. · 2023

Objectives Developmentally specified measures that identify clinically salient irritability are needed for early school‐age youth to meaningfully capture this transdiagnostic risk factor for psychopathology. Thus, the current study modeled…

MAPping affective dimensions of behavior: Methodologic and pragmatic advancement of the Multidimensional Assessment Profiles scales Open

Jillian Lee Wiggins, Amy Krain Roy, Lauren S. Wakschlag · 2023

Rigorous validation of the full developmentally sensitive normal:abnormal spectrum, including evaluating the incremental value of age‐specific behaviors, is necessary for nuanced characterization of dimensional features of psychopathology.…

A pragmatic, clinically optimized approach to characterizing adolescent irritability: Validation of parent‐ and adolescent reports on the Multidimensional Assessment Profile Scales—Temper Loss Scale Open

Nathan Kirk, Emily Hirsch, Tasmia Alam, Lauren S. Wakschlag, Jillian Lee Wiggins , et al. · 2023

Objectives Heightened irritability in adolescence is an impairing symptom that can lead to negative outcomes in adulthood, but effective screening tools are lacking. This study aimed to derive clinically‐optimized cutoff scores using the M…

Review: Defining Positive Emotion Dysregulation: Integrating Temperamental and Clinical Perspectives Open

Alecia C. Vogel, Melissa A. Brotman, Amy Krain Roy, Susan B. Perlman · 2022

Longitudinal Change in Adolescent Depression and Anxiety Symptoms from before to during the <span>COVID</span> ‐19 Pandemic Open

Marjolein E.A. Barendse, Jessica Flannery, Caitlin Cavanagh, Melissa Aristizabal, Stephen P. Becker , et al. · 2022

This study aimed to examine changes in depression and anxiety symptoms from before to during the first 6 months of the COVID‐19 pandemic in a sample of 1,339 adolescents (9–18 years old, 59% female) from three countries. We also examined i…

Parental Factors That Confer Risk and Resilience for Remote Learning Outcomes During the COVID-19 Pandemic Among Children With and Without Attention-Deficit/Hyperactivity Disorder Open

Melanie Silverman, Jill Stadterman, Danny Lorenzi, Leah Feuerstahler, Emily Hirsch , et al. · 2022

Objective: To test whether parental factors including internalizing symptoms, parenting style, and confidence in assisting with remote learning conferred risk/resilience for children with/without ADHD’s learning and emotional outcomes duri…

A preliminary examination of key strategies, challenges, and benefits of remote learning expressed by parents during the COVID-19 pandemic. Open

Amy Krain Roy, Rosanna Breaux, Emma Sciberras, Pooja Patel, Erica Ferrara , et al. · 2022

Among the many impacts of the Coronavirus disease (COVID-19) pandemic, one of the most dramatic was the immediate closure of in-person schooling in March/April 2020 when parents were faced with much greater responsibility in supporting the…

The Psychological, Academic, and Economic Impact of COVID-19 on College Students in the Epicenter of the Pandemic Open

Jazmin A. Reyes‐Portillo, Carrie Masia Warner, Emily A. Kline, Michael T. Bixter, Brian C. Chu , et al. · 2022

Initial research has indicated that college students have experienced numerous stressors as a result of the pandemic. The current investigation enrolled the largest and most diverse sample of college students to date ( N = 4714) from unive…

Measuring Emotion Dysregulation in Children With Attention-Deficit/Hyperactivity Disorder: Revisiting the Factor Structure of the Emotion Regulation Checklist Open

Melanie Silverman, Randi Bennett, Leah Feuerstahler, Jill Stadterman, Anthony Steven Dick , et al. · 2021

Mediating Role of The Default Mode Network On Parental Acceptance/Warmth and Psychopathology in Youth Open

Kaley Davis, Emily Hirsch, Dylan G. Gee, Margaret S. Andover, Amy Krain Roy · 2021

Humans are reliant on their caregivers for an extended period of time, offering numerous opportunities for environmental factors, such as parental attitudes and behaviors, to impact brain development. The default mode network is a neural s…

Longitudinal change in adolescent depression and anxiety symptoms from before to during the COVID-19 pandemic: A collaborative of 12 samples from 3 countries Open

Marjolein E.A. Barendse, Jessica Flannery, Cait Cavanagh, Melissa Aristizabal, Stephen P. Becker , et al. · 2021

Published paper can be found at https://doi.org/10.1111/jora.12781. This study aimed to examine changes in depression and anxiety symptoms from before to during the first six months of the COVID-19 pandemic in a sample of 1,339 adolescents…

Decomposing complex links between the childhood environment and brain structure in school-aged youth Open

Seok‐Jun Hong, Lucinda M. Sisk, Camila Caballero, Anthony Mekhanik, Amy Krain Roy , et al. · 2021

Childhood experiences play a profound role in conferring risk and resilience for brain and behavioral development. However, how different facets of the environment shape neurodevelopment remains largely unknown. Here we sought to decompose…

Decomposing complex links between the childhood environment and brain structure in school-aged youth Open

Seok‐Jun Hong, Lucinda M. Sisk, Camila Caballero, Anthony Mekhanik, Amy Krain Roy , et al. · 2020

Childhood experiences play a profound role in conferring risk and resilience for brain and behavioral development. However, how different facets of the environment shape neurodevelopment remains largely unknown. Here we sought to decompose…

A Preliminary Investigation of the Effects of a Western Diet on Hippocampal Volume in Children Open

Jill Stadterman, Kyrstin Belthoff, Ying Han, Amanda D. Kadesh, Yuliya Yoncheva , et al. · 2020

Introduction: Over the course of the 20th century, there has been a sharp increase in the consumption of saturated fat and refined sugars. This so-called "western diet" (WD) has been extensively linked to biological alterations and …

Functional connectivity of the anterior insula associated with intolerance of uncertainty in youth Open

Mariah DeSerisy, Alec Musial, Jonathan S. Comer, Amy Krain Roy · 2020

The Contribution of Sensory Sensitivity to Emotional Lability in Children with ADHD Symptoms Open

Mariah DeSerisy, Emily Hirsch, Amy Krain Roy · 2019

Emotional lability and sensory sensitivity have been shown to contribute to the overall clinical picture in children with attention deficit hyperactivity disorder (ADHD; Dunn & Bennett, 2002; Sobanski et al., 2010). Further, both of these …

Heterogeneity of the Anxiety-Related Attention Bias: A Review and Working Model for Future Research Open

Tracy A. Dennis‐Tiwary, Amy Krain Roy, Samantha Denefrio, Sarah Myruski · 2019

Anxiety-related attention bias (AB) has been studied for several decades as a clinically relevant output of the dynamic and complex threat-detection and -response system. Despite research enthusiasm for the construct of AB, current theorie…

Evidence of Altered Habenular Intrinsic Functional Connectivity in Pediatric ADHD Open

Melissa Arfuso, Ramiro Salas, F. Xavier Castellanos, Amy Krain Roy · 2019

Objective: The habenula is a small region in the epithalamus that contributes to the regulation of midbrain dopaminergic circuits implicated in attention-deficit hyperactivity disorder (ADHD). This investigation aims to evaluate the intrin…

Altered intrinsic functional connectivity of the cingulate cortex in children with severe temper outbursts Open

Amy Krain Roy, Randi Bennett, Jonathan Posner, Leslie A. Hulvershorn, F. Xavier Castellanos , et al. · 2017

Severe temper outbursts (STO) in children are associated with impaired school and family functioning and may contribute to negative outcomes. These outbursts can be conceptualized as excessive frustration responses reflecting reduced emoti…

Distinct Functional Connectivities Predict Clinical Response with Emotion Regulation Therapy Open

David M. Fresco, Amy Krain Roy, Samantha Adelsberg, Saren H. Seeley, Emmanuel García-Lesy , et al. · 2017

Despite the success of available medical and psychosocial treatments, a sizable subgroup of individuals with commonly co-occurring disorders, generalized anxiety disorder (GAD) and major depressive disorder (MDD), fail to make sufficient t…

Alterations in amygdala–prefrontal circuits in infants exposed to prenatal maternal depression Open

Jonathan Posner, Jiook Cha, Amy Krain Roy, Bradley S. Peterson, Ravi Bansal , et al. · 2016

Prenatal exposure to maternal depression is common and puts offspring at risk for developing a range of neuropsychiatric disorders. Despite its prevalence and adverse associations, neurobiological processes by which prenatal maternal depre…

Disruptive Mood Dysregulation Disorder (DMDD): An RDoC perspective Open

Erica Meyers, Mariah DeSerisy, Amy Krain Roy · 2016

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