Amy Tunali
YOU?
Author Swipe
View article: Comparative genomic analysis of emerging non-typeable <i>Haemophilus influenzae</i> (NTHi) causing emerging septic arthritis in Atlanta
Comparative genomic analysis of emerging non-typeable <i>Haemophilus influenzae</i> (NTHi) causing emerging septic arthritis in Atlanta Open
Background Haemophilus influenzae is a Gram-negative bacterium that can exist as a commensal organism or cause a range of diseases, from ear infections to invasive conditions like meningitis. While encapsulated H. influenzae strains have h…
View article: Serotype-specific pneumococcal invasiveness: a global meta-analysis of paired estimates of disease incidence and carriage prevalence
Serotype-specific pneumococcal invasiveness: a global meta-analysis of paired estimates of disease incidence and carriage prevalence Open
Background Serotype-specific estimates of pneumococcal invasiveness used in pneumococcal carriage transmission models to predict changes in disease incidence post-vaccination are largely derived from high-income settings. We conducted a sy…
View article: 419. Changing Epidemiology of Pediatric Invasive Group A <i>Streptococcus</i> Infections in the United States, 2004-2022
419. Changing Epidemiology of Pediatric Invasive Group A <i>Streptococcus</i> Infections in the United States, 2004-2022 Open
Background Recent reports from children’s hospitals of increasing pediatric invasive Group A Streptococcus (iGAS) infections triggered national concern. Clindamycin and penicillin dual therapy is often recommended for iGAS, which is life-t…
View article: 1281. Ongoing Transmission of Clonal Strains of Invasive Nontypeable <i>Haemophilus influenzae</i> Disproportionately Affecting Persons with HIV in Metropolitan Atlanta, 2019—2022
1281. Ongoing Transmission of Clonal Strains of Invasive Nontypeable <i>Haemophilus influenzae</i> Disproportionately Affecting Persons with HIV in Metropolitan Atlanta, 2019—2022 Open
Background Nontypeable Haemophilus influenzae (NTHi) is a genetically diverse pathogen that typically causes mucosal infections or invasive NTHi (iNTHi) disease in persons at the extremes of age. In 2017-2018, we reported a significant inc…
View article: Evaluation of Asymptomatic <i>Bordetella</i> Carriage in a Convenience Sample of Children and Adolescents in Atlanta, Georgia, United States
Evaluation of Asymptomatic <i>Bordetella</i> Carriage in a Convenience Sample of Children and Adolescents in Atlanta, Georgia, United States Open
Few data exist on asymptomatic carriage of Bordetella species among populations receiving acellular pertussis vaccine. We conducted a cross-sectional study among acellular-vaccinated children presenting to an emergency department (ED). Bor…
View article: Pneumococcal infections in children with sickle cell disease before and after pneumococcal conjugate vaccines
Pneumococcal infections in children with sickle cell disease before and after pneumococcal conjugate vaccines Open
Children with sickle cell disease (SCD) are at increased risk of invasive pneumococcal disease (IPD). Over 25 years, the Georgia Emerging Infections Program/Centers for Disease Control and Prevention Active Bacterial Core Surveillance netw…
View article: Phylogenomic Comparison of <i>Neisseria gonorrhoeae</i> Causing Disseminated Gonococcal Infections and Uncomplicated Gonorrhea in Georgia, United States
Phylogenomic Comparison of <i>Neisseria gonorrhoeae</i> Causing Disseminated Gonococcal Infections and Uncomplicated Gonorrhea in Georgia, United States Open
Disseminated gonococcal infection (DGI) is a rare complication caused by the systemic dissemination of Neisseria gonorrhoeae to normally sterile anatomical sites. Little is known about the genetic diversity of DGI gonococcal strains and ho…
View article: Surveillance for Disseminated Gonococcal Infections, Active Bacterial Core Surveillance (ABCs)—United States, 2015–2019
Surveillance for Disseminated Gonococcal Infections, Active Bacterial Core Surveillance (ABCs)—United States, 2015–2019 Open
Background Disseminated gonococcal infections (DGIs) are thought to be uncommon; surveillance is limited, and case reports are analyzed retrospectively or in case clusters. We describe the population-level burden of culture-confirmed DGIs …
View article: Invasive Nontypeable<i>Haemophilus influenzae</i>Infection Among Adults With HIV in Metropolitan Atlanta, Georgia, 2008-2018
Invasive Nontypeable<i>Haemophilus influenzae</i>Infection Among Adults With HIV in Metropolitan Atlanta, Georgia, 2008-2018 Open
Among persons with HIV in Atlanta, the incidence of invasive nontypeable H influenzae infection increased significantly from 2017-2018 compared with 2008-2016. Two unique but genetically related clonal strains were identified and were asso…
View article: Evaluating Household Transmission of Invasive Group A <i>Streptococcus</i> Disease in the United States Using Population-based Surveillance Data, 2013–2016
Evaluating Household Transmission of Invasive Group A <i>Streptococcus</i> Disease in the United States Using Population-based Surveillance Data, 2013–2016 Open
Using population-based surveillance data, we quantified the secondary invasive group A Streptococcus disease risk among household contacts. The disease risk in the 30 days postexposure to an index-case patient was highest among individuals…
View article: P634 Surveillance for disseminated gonococcal infections, active bacterial core surveillance (ABCs) – united states, 2015–2018
P634 Surveillance for disseminated gonococcal infections, active bacterial core surveillance (ABCs) – united states, 2015–2018 Open
Background Disseminated gonococcal infections (DGI) are uncommon; occurring in an estimated 0.5–3% of Neisseria gonorrhoeae (GC) cases. DGI surveillance is limited and case reports are often analyzed retrospectively or in case clust…
View article: Streptococcus pneumoniae colonization after introduction of 13-valent pneumococcal conjugate vaccine for US adults 65 years of age and older, 2015–2016
Streptococcus pneumoniae colonization after introduction of 13-valent pneumococcal conjugate vaccine for US adults 65 years of age and older, 2015–2016 Open
Pneumococcal carriage among non-institutionalized adults ≥65 years of age was very low. Less than 0.5% of both vaccinated and unvaccinated individuals in our study carried vaccine-type serotypes. Over a decade of PCV vaccination of childre…
View article: 1234. Racial Disparities in Invasive Staphylococcus aureus (iSA) Disease in Metropolitan Atlanta, a Population-Based Assessment, 2016
1234. Racial Disparities in Invasive Staphylococcus aureus (iSA) Disease in Metropolitan Atlanta, a Population-Based Assessment, 2016 Open
Background Disparities in incidence of invasive methicillin-resistant S. aureus (iMRSA) infections have been examined, suggesting that differences were in part driven by socio-economic factors. An analysis was conducted to determine whethe…
View article: Emergence of Localized Serogroup W Meningococcal Disease in the United States — Georgia, 2006–2016
Emergence of Localized Serogroup W Meningococcal Disease in the United States — Georgia, 2006–2016 Open
Several countries in Europe and Australia are reporting an increasing incidence of Neisseria meningitidis serogroup W (NmW) as a consequence of the rapid expansion of a single NmW clone belonging to clonal complex 11 (1-5). Because this cl…
View article: Socioeconomic Factors Explain Racial Disparities in Invasive Community-Associated Methicillin-Resistant Staphylococcus aureus Disease Rates
Socioeconomic Factors Explain Racial Disparities in Invasive Community-Associated Methicillin-Resistant Staphylococcus aureus Disease Rates Open
The racial disparity in invasive community-associated MRSA rates was largely explained by socioeconomic factors. The specific factors that underlie the association between census tract-level socioeconomic measures and MRSA incidence, which…
View article: Using whole genome sequencing to identify resistance determinants and predict antimicrobial resistance phenotypes for year 2015 invasive pneumococcal disease isolates recovered in the United States
Using whole genome sequencing to identify resistance determinants and predict antimicrobial resistance phenotypes for year 2015 invasive pneumococcal disease isolates recovered in the United States Open
Our whole genome sequence (WGS) pipeline was assessed for accurate prediction of antimicrobial phenotypes. For 2316 invasive pneumococcal isolates recovered during 2015 we compared WGS pipeline data to broth dilution testing (BDT) for 18 a…
View article: Socioeconomic Factors Explain Racial Disparities in Community-Associated Methicillin-Resistant Staphyloccocus aureus Disease Rates
Socioeconomic Factors Explain Racial Disparities in Community-Associated Methicillin-Resistant Staphyloccocus aureus Disease Rates Open