Ana Nikolić
YOU?
Author Swipe
View article: Spatial epigenomic niches underlie glioblastoma cell state plasticity
Spatial epigenomic niches underlie glioblastoma cell state plasticity Open
SUMMARY IDH -wildtype glioblastoma (GBM) is an aggressive brain tumor with poor survival and few therapeutic options. Transcriptionally-defined cell states coexist in GBM and occupy defined regions of the tumor. Evidence indicates that GBM…
View article: Maize transcriptome profiling reveals low temperatures affect photosynthesis during the emergence stage
Maize transcriptome profiling reveals low temperatures affect photosynthesis during the emergence stage Open
Introduction Earlier sowing is a promising strategy of ensuring sufficiently high maize yields in the face of negative environmental factors caused by climate change. However, it leads to the low temperature exposure of maize plants during…
View article: Comprehensive Characterization via Molecular Imaging, Longitudinal Multisite Sampling, and Autoptic Work-up in Advanced Small Cell Lung Cancer Undergoing SSTR-Directed Radiopharmaceutical Therapy
Comprehensive Characterization via Molecular Imaging, Longitudinal Multisite Sampling, and Autoptic Work-up in Advanced Small Cell Lung Cancer Undergoing SSTR-Directed Radiopharmaceutical Therapy Open
Despite the addition of immune checkpoint blockade to first-line chemotherapy, the prognosis for patients with small cell lung cancer (SCLC) is still devastating. For the subset of SCLC with somatostatin receptor (SSTR) overexpression, rad…
View article: Genetic diversity analysis of white maize inbred lines using SNP markers
Genetic diversity analysis of white maize inbred lines using SNP markers Open
White maize (Zea mays L.) represents an important genetic resource with significant nutritional and agronomic value. Understanding its genetic diversity is essential for the conservation of local germplasm and the development of improved c…
View article: Experience of rescue therapy with [177Lu]Lu-rhPSMA-10.1 in patients with primary or acquired resistance to [177Lu]Lu-PSMA-I&T
Experience of rescue therapy with [177Lu]Lu-rhPSMA-10.1 in patients with primary or acquired resistance to [177Lu]Lu-PSMA-I&T Open
Purpose Radioligand therapy is an increasingly important option for the treatment of metastatic castrate-resistant prostate cancer (mCRPC). Radiohybrid ligands targeting prostate-specific membrane antigen (PSMA) are a novel group of theran…
View article: Concept and feasibility of the Augsburg Longitudinal Plasma Study (ALPS) – a prospective trial for comprehensive liquid biopsy-based longitudinal monitoring of solid cancer patients
Concept and feasibility of the Augsburg Longitudinal Plasma Study (ALPS) – a prospective trial for comprehensive liquid biopsy-based longitudinal monitoring of solid cancer patients Open
Objectives Liquid biopsy (LBx) provides diagnostic, prognostic and predictive insights for malignant diseases and offers promising applications regarding tumor burden, tumor heterogeneity and clonal evolution. Methods The Augsburg Longitud…
View article: Examining the presence and frequency of impulse control disorders in Wilson's disease
Examining the presence and frequency of impulse control disorders in Wilson's disease Open
Introduction: Wilson's disease is a rare, hereditary disease, which leads to the accumulation of copper, primarily in the liver and brain, due to the impossibility of its excretion from the body. The disease is presented with hepatic, neur…
View article: Supplementary Fig. S1 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S1 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Quality control analysis of spatial transcriptomics.
View article: Supplementary Fig. S10 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S10 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Survival analysis of GBM patients in public databases.
View article: Supplementary Fig. S2 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S2 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Spatial gene expression of ECM molecules in mouse brain tumors.
View article: Supplementary Fig. S3 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S3 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Quality control analysis of scRNA-seq.
View article: Supplementary Fig. S6 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S6 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Additional analysis of human GBM specimens for biglycan and BTICs.
View article: Supplementary Data from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Data from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Legends of Supplementary figures and tables.
View article: Supplementary Fig. S2 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S2 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Spatial gene expression of ECM molecules in mouse brain tumors.
View article: Graphical abstract from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Graphical abstract from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Graphical abstract. A multi-omics analysis of the glioblastoma tumor microenvironment revealed that biglycan, predominantly expressed by inflammatory BTICs, drives tumor growth. The graphics were generated with Biorender.com.
View article: Supplementary Fig. S4 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S4 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Additional analysis showing clusters of scRNA-seq analysis with more stemness profiles.
View article: Supplementary Fig. S5 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S5 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Spatial expression of stemness genes in tumor areas.
View article: Graphical abstract from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Graphical abstract from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Graphical abstract. A multi-omics analysis of the glioblastoma tumor microenvironment revealed that biglycan, predominantly expressed by inflammatory BTICs, drives tumor growth. The graphics were generated with Biorender.com.
View article: Data from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Data from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Glioblastomas (GBM) are aggressive brain tumors with extensive intratumoral heterogeneity that contributes to treatment resistance. Spatial characterization of GBMs could provide insights into the role of the brain tumor microenvironment i…
View article: Supplementary Fig. S8 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S8 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Additional analysis of in vitro proliferative effects of biglycan.
View article: Supplementary Fig. S4 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S4 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Additional analysis showing clusters of scRNA-seq analysis with more stemness profiles.
View article: Supplementary Fig. S6 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S6 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Additional analysis of human GBM specimens for biglycan and BTICs.
View article: Supplementary Data from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Data from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Legends of Supplementary figures and tables.
View article: Supplementary Fig. S8 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S8 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Additional analysis of in vitro proliferative effects of biglycan.
View article: Supplementary Fig. S7 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S7 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Perivascular location assessments of biglycan expression in the human GBM microenvironment.
View article: Supplementary Table S1 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Table S1 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Characterization of patients whose resected tissues were used for confocal microscopy.
View article: Supplementary Fig. S9 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells
Supplementary Fig. S9 from Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor–Initiating Cells Open
Additional analysis LRP6 and the Wnt/β-catenin pathway activation in BTICs.