Ana Gordon
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View article: From juvenile to adult: investigating miRNAs, gene expression, and the juvenile cone in olive development
From juvenile to adult: investigating miRNAs, gene expression, and the juvenile cone in olive development Open
The long juvenile phase in perennials hinders rapid breeding, highlighting the need for early selection markers. Some species, such as the olive tree ( Olea europaea L.), develop a juvenile cone, where adult tissue forms in the upper and p…
View article: Afamin and Apolipoprotein F Associated With Liver Steatosis From People Living With <scp>HIV</scp>: A Discovery Study
Afamin and Apolipoprotein F Associated With Liver Steatosis From People Living With <span>HIV</span>: A Discovery Study Open
Introduction Liver steatosis (LS) is a condition that is characterised by hepatic fat accumulation unrelated to significant alcohol consumption. This study explored the serum proteomic profile associated with LS in people living with HIV (…
View article: Localization, traffic and function of Rab34 in adipocyte lipid and endocrine functions
Localization, traffic and function of Rab34 in adipocyte lipid and endocrine functions Open
Background Excessive lipid accumulation in the adipose tissue in obesity alters the endocrine and energy storage functions of adipocytes. Adipocyte lipid droplets represent key organelles coordinating lipid storage and mobilization in thes…
View article: Rab18 Drift in Lipid Droplet and Endoplasmic Reticulum Interactions of Adipocytes under Obesogenic Conditions
Rab18 Drift in Lipid Droplet and Endoplasmic Reticulum Interactions of Adipocytes under Obesogenic Conditions Open
The adipose tissue stores excess energy in the form of neutral lipids within adipocyte lipid droplets (LDs). The correct function of LDs requires the interaction with other organelles, such as the endoplasmic reticulum (ER) as well as with…
View article: A novel Microproteomic Approach Using Laser Capture Microdissection to Study Cellular Protrusions
A novel Microproteomic Approach Using Laser Capture Microdissection to Study Cellular Protrusions Open
Cell–cell communication is vital to multicellular organisms, and distinct types of cellular protrusions play critical roles during development, cell signaling, and the spreading of pathogens and cancer. The differences in the structure and…
View article: Myosin-X is essential to the intercellular spread of HIV-1 Nef through tunneling nanotubes
Myosin-X is essential to the intercellular spread of HIV-1 Nef through tunneling nanotubes Open
Tunneling nanotubes (TNTs) are intercellular structures that allow for the passage of vesicles, organelles, genomic material, pathogenic proteins and pathogens. The unconventional actin molecular motor protein Myosin-X (Myo10) is a known i…
View article: A Novel Cell Fixation Method that Greatly Enhances Protein Identification in Microproteomic Studies Using Laser Capture Microdissection and Mass Spectrometry
A Novel Cell Fixation Method that Greatly Enhances Protein Identification in Microproteomic Studies Using Laser Capture Microdissection and Mass Spectrometry Open
Microproteomic studies have improved our knowledge of cell biology. Yet, with mass spectrometry (MS) analysis, accuracy can be lost for protein identification and quantification when using heterogeneous samples. Laser capture microdissecti…
View article: Understanding the regulation of pituitary progesterone receptor expression and phosphorylation
Understanding the regulation of pituitary progesterone receptor expression and phosphorylation Open
Administration of human FSH (hFSH) during the diestrus phase in cyclic rats is followed by a reduction in the preovulatory LH surge. This inhibitory action of FSH involves a decrease in the stimulatory effect of gonadotrope progesterone re…
View article: Persistence of Pathological Distribution of NK Cells in HIV-Infected Patients with Prolonged Use of HAART and a Sustained Immune Response
Persistence of Pathological Distribution of NK Cells in HIV-Infected Patients with Prolonged Use of HAART and a Sustained Immune Response Open
Despite the prolonged and effective use of HAART, HIV-infected patients do not fully reconstitute the distribution of NK cells. Length of time with an undetectable viral load was related to greater recovery of NKp30/NKp46 receptors.