Explanipedia

Antibiofilm Effects of N-Acetyl Cysteine on Staphylococcal Biofilm in Patients with Chronic Rhinosinusitis Open

Ana Jotić, Ivana Ćirković, Dragana D. Božić, Katarina Savić Vujović, Jovica Milovanović , et al. · 2025

Staphylococcal bacterial biofilm plays an important role in the pathogenesis and bacterial persistence of chronic rhinosinusitis. N-acetyl cysteine (NAC) has an inhibitory role in biofilm formation, suppressing adhesion and matrix producti…

Differentiated Thyroid Cancer Long-Term Outcomes and Risk Stratification in Pediatric and Adolescent Patients: A 44-Year Retrospective Study Open

Marko Buta, Nada Santrač, Merima Goran, Nikola Jeftić, Jovan Raketic , et al. · 2025

Background: Differentiated thyroid cancer (DTC) in children and adolescents is a rare but significant malignancy, often presenting at more advanced stages compared to adults, although it is associated with favorable long-term outcomes. Thi…

Differentiated Thyroid Cancer Long-Term Outcomes and Risk Stratification in Pediatric and Adolescent Patients: A 44-Year Retrospective Study Open

Marko Buta, Nada Santrač, Merima Goran, Nikola Jeftić, Jovan Raketic , et al. · 2025

Introduction: Differentiated thyroid cancer (DTC) in children and adolescents is a ra-re, but significant malignancy, often presenting at more advanced stages compared to adults, although it is associated with favorable long-term outcomes.…

Functional assessment of cancer therapy – head & neck (FACT-HN) translation and validation in Serbian Open

Maša Petrović, Bojana Šalović, Ana Tomić, Tanja Jesic-Petrovic, Aleksandar Matejic , et al. · 2025

An anesthesiologist's perspective on advancements in perioperative analgesia Open

Dragana Milivojevic, A Obreski, Tjaša Ivošević, Katarina Savić Vujović, Ana Jotić · 2025

Introduction. Effective perioperative pain management remains a cornerstone of modern anesthesiology, directly influencing patient outcomes, recovery times, and overall satisfaction. This paper aims to explore advancements in perioperative…

Idiopathic sudden sensorineural hearing loss: Current insights into etiology, diagnosis, and management Open

Ljiljana Čvorović, Ana Jotić, Bojana Bukurov, Nebojša Đurić · 2025

Idiopathic sudden sensorineural hearing loss (ISSNHL) is a distinct otologic emergency characterized by an abrupt onset of unilateral sensorineural hearing loss, typically occurring within 72 hours and lacking any identifiable cause. Altho…

Antibiofilm Effects of Novel Compounds in Otitis Media Treatment: Systematic Review Open

Ana Jotić, Katarina Savić Vujović, Andja Ćirković, Dragana D. Božić, Snežana Brkić , et al. · 2024

Otitis media (OM) is a frequent disease with incidence rate of 5300 cases per 100,000 people. Recent studies showed that polymicrobial biofilm formation represents a significant pathogenic mechanism in recurrent and chronic forms of OM. Bi…

Role of Oxidative Stress and Inflammation in Postoperative Complications and Quality of Life After Laryngeal Cancer Surgery Open

Andjela Zivkovic, Ana Jotić, Ivan Dožić, Simona Randjelovic, Ivana Ćirković , et al. · 2024

(1) Background: Laryngeal surgery due to carcinoma leads to significant tissue disruption, cellular injury, and inflammation. This leads to increased levels of reactive oxygen species (ROS), causing oxidative damage that can influence qual…

Friend or Foe? Exploring the Role of Cytomegalovirus (HCMV) Infection in Head and Neck Tumors Open

Aleksandar Trivić, Jovica Milovanović, Djurdjina Kablar, Ana Tomić, Miljan Folić , et al. · 2024

Although not regarded as an oncogenic pathogen, the human cytomegalovirus (HCMV) has been associated with a wide array of malignancies. Conversely, a number of studies report on possible anti-tumor properties of the virus, apparently media…

Pharmacological management of postoperative pain Open

Katarina Savić Vujović, Sonja Vučković, Branislava Medić, Dragana Srebro, Ana Jotić · 2024

Postoperative pain is a widespread and underestimated problem both in Serbia and globally. Numerous studies conducted in countries with advanced healthcare systems have shown that even in the 21st century, postoperative pain is not adequat…

Ketamine, an Old–New Drug: Uses and Abuses Open

Katarina Savić Vujović, Ana Jotić, Branislava Medić, Dragana Srebro, A. Vujovic , et al. · 2023

Ketamine as an old–new drug has a variety of clinical implications. In the last 30 years, ketamine has become popular for acute use in humans. Ketamine in standard doses is principally utilized for the induction and maintenance of surgical…

In Vitro Antibiofilm Effect of N-Acetyl-L-cysteine/Dry Propolis Extract Combination on Bacterial Pathogens Isolated from Upper Respiratory Tract Infections Open

Dragana D. Božić, Ivana Ćirković, Jovica Milovanović, Biljana Bufan, Miljan Folić , et al. · 2023

Bacterial biofilms play an important role in the pathogenesis of chronic upper respiratory tract infections. In addition to conventional antimicrobial therapy, N-acetyl-L-cysteine (NAC) and propolis are dietary supplements that are often r…

Ketamine, an Old–New Drug: Uses and Abuses Open

Katarina Savić Vujović, Ana Jotić, Branislava Medić, Dragana Srebro, A. Vujovic , et al. · 2023

Ketamine as an old - new drug has variety of clinical implications. In the last 30 years, ketamine has become popular for acute use in humans. Ketamine at standard doses is principally utilized for the induction and maintenance in surgical…

FIP Seville 2022: Clinical Biology Open

Amaka M. Awanye, Chidozie N. E. Ibezim, Catherine Stanley, I. O. Okonko, Nkechi Eucharia Egbe , et al. · 2023

Accepted abstracts under the theme: Clinical Biology (n=8)

Oxidative Stress and Inflammation Biomarkers in Postoperative Pain Modulation in Surgically Treated Patients with Laryngeal Cancer—Pilot Study Open

Katarina Savić Vujović, Andjela Zivkovic, Ivan Dožić, Andja Ćirković, Branislava Medić , et al. · 2023

(1) Background: Surgical treatment of laryngeal carcinoma includes different types of laryngectomies with neck dissection. Surgical tissue damage triggers an inflammatory response, leading to the release of pro-inflammatory molecules. This…

Adoption of clinical practice guidelines in cases of benign paroxysmal positional vertigo Open

Bojana Bukurov, Dragana Nenezic, Danilo Pot, Nemanja Radivojevic, Tjaša Ivošević , et al. · 2023

Challenges of adult users of hearing amplification during the Covid-19 pandemic Open

Mina Nikolić, Sanja Ostojić-Zeljković, Ana Jotić, Sanja Đoković · 2023

Introduction. The Covid-19 pandemic has considerably affected many aspects of human life, especially healthcare and social services. The contacts of elderly people with family and friends, as well as their social activities, have been dras…

Cervical plexus block - safe anesthesia for the patients with massive mediastinal lymphadenopathy Open

Tjaša Ivošević, Ljiljana Ranković-Ničić, Ljubiša Mirić, Ana Jotić, Bojana Bukurov · 2023

Introduction. General anesthesia is frequently employed in neck surgery procedures. However, in patients at high risk for general anesthesia, regional anesthesia options, such as the superficial cervical plexus block, warrant careful consi…

The role of 18F-FDG PET/CT in the follow-up of laryngeal cancer after treatment Open

Jelena Petrović, Dragana Šobić-Šaranović, Jovica Milovanović, Ana Jotić, Strahinja Odalović , et al. · 2023

Introduction: The aim of this investigation was to estimate the diagnostic performance of positron emission tomography/computed tomography using fluorine-18 fluoro-deoxyglucose (18F-FDG PET/CT) in the follow-up of post-treatment laryngeal …

The Expression of Hypoxia-Related Biomarkers: A Significance of HIF-1α C1772T Polymorphism as Predictor of Laryngeal Carcinoma Relapse Open

Miljan Folić, Ana Banko, Vera N Todorovic, Nela Puškaš, Jovica Milovanović , et al. · 2022

Introduction The association between the expression of HIF-1α in the laryngeal carcinoma and the prognosis of disease is quite well documented, but the significance of HIF-1α C1772T polymorphism and its relation to disease phenotype have t…

Immune Cell and Biochemical Biomarkers in Advanced Laryngeal Cancer Open

Ana Jotić, Jovica Milovanović, Katarina Savić Vujović, Zorana Radin, Branislava Medić , et al. · 2022

Objective The aim of this study was to evaluate cell and biochemical biomarkers and establish their prognostic value in patients with advanced laryngeal cancer. Material and Methods A prospective study included 52 patients with advanced la…

Symptoms of depression, anxiety and stress in patients with chronic otitis media Open

Ana Jotić, Ana Opanković, Zorana Z. Radin, Ljiljana Čvorović, Katarina Savić Vujović , et al. · 2022

Purpose Persistent symptoms of chronic otitis media cause limitations in daily routine and social interactions, influencing significantly patients’ quality of life and mental health. The purpose of the study was to assess the intensity dep…

Effectiveness of the Treatment of Rhinogenic Headache Caused by Intranasal Contact Open

Miljan Folić, Aleksandra Barać, A.B. Ugrinovic, Ana Jotić, Aleksandar Trivić , et al. · 2021

Objectives: The aim of the study is to evaluate the effectiveness of the surgical and nonsurgical treatment of headache caused by contact points (CPs) between the nasal septum and inferior or middle turbinate. Methods: The research was des…

Large neck metastasis with unknown primary tumor: A case report Open

Milovan Dimitrijević, Bojana Bukurov, Ana Jotić · 2021

Introduction. Metastatic head and neck carcinoma (HNC) from an unknown primary tumor is defined as a metastatic disease in the neck?s lymph nodes without evidence of a primary tumor after appropriate investigation. Multiple national guidel…

Rational use of antibiotics during the COVID-19 pandemic Open

Jovica Milovanović, Ana Jotić, Zorana Radin, Ivana Ćirković · 2021

Introduction/Aim: The global COVID-19 pandemic has long been considered an emergency, with the number of cases growing exponentially, despite constant efforts to control the infection. Although the disease is caused by the SARS-CoV-2 virus…

Otorhinolaryngology emergency department hospitalizations in a secondary medical center Open

Zorana Radin, Dejan Bakic, Dimitrije Ilic, Ana Jotić · 2020

Introduction/Objective. The overall number of emergency department visits, including otorhinolaryngology, has increased. Due to population growth, industry and traffic expansion, workload of the otorhinolaryngology emergency department is …

Predictors of Complications Occurrence Associated With Emergency Surgical Tracheotomy Open

Ana Jotić, Jovica Milovanović, Aleksandar Trivić, Miljan Folić, Sanja Krejović-Trivić , et al. · 2020

Objective In emergency airway management, the occurrence of surgical tracheotomy complications is increased and may be fatal for the patient. However, the factors that play a role in complication occurrence and lead to lethal outcome are n…

Management of Orbital Complications of Acute Rhinosinusitis in Pediatric Patients Open

Aleksandar Trivić, Müge Çevik, Miljan Folić, Sanja Krejović-Trivić, Salvatore Rubino , et al. · 2019

Background: The major clinical dilemma managing acute rhinosinusitis (ARS) in pediatric population is distinguishing uncomplicated rhinosinusitis from a complicated bacterial ARS and orbital complications, the latter requiring antimicrobia…

Pain Management After Surgical Tonsillectomy: Is There a Favorable Analgesic? Open

Ana Jotić, Katarina Savić Vujović, Jovica Milovanović, A. Vujovic, Zorana Radin , et al. · 2019

The aim of this study was to examine how ibuprofen and paracetamol prevent pain after cold-steel extracapsular tonsillectomy in children. Also, we examined the relation between age, gender, nausea, postoperative bleeding, antibiotic use, t…

Relationship between socio-demographic characteristics and vocal fold nodules, polyps and oedema Open

Jovica Milovanović, Maja Vukašinović‐Sekulić, Ana Jotić, Hristina Vlajinac, Andjela Milovanović , et al. · 2018

The aim of our study was to compare socio-demographic characteristics of vocal fold nodules, polyps and oedema. The study included patients diagnosed for the first time with vocal fold nodules, polyps and oedema at the Communication Disord…

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