Ana Luísa Höfling-Lima
YOU?
Author Swipe
View article: Ocular bacterial microbiome analysis by next-generation sequencing in patients with Stevens-Johnson syndrome and Sjögren's disease: associations with dry eye indices
Ocular bacterial microbiome analysis by next-generation sequencing in patients with Stevens-Johnson syndrome and Sjögren's disease: associations with dry eye indices Open
The ocular surface microbiome plays a crucial role in maintaining immune homeostasis, and its disruption may contribute to mucosal inflammation and autoimmunity. This pilot exploratory study investigated and compared the ocular surface bac…
View article: Intracameral Antibiotic Prophylaxis and Surgical Expertise: Key Determinants in Endophthalmitis After Cataract Surgery
Intracameral Antibiotic Prophylaxis and Surgical Expertise: Key Determinants in Endophthalmitis After Cataract Surgery Open
Background/Objectives Postoperative endophthalmitis is a rare but severe complication of cataract surgery. Intracameral moxifloxacin prophylaxis has been widely adopted, but concerns remain regarding bacterial resistance and clinical outco…
View article: Correction: Postoperative endophthalmitis treatment with antibiotics associated or not with pars plana vitrectomy: a randomized clinical trial
Correction: Postoperative endophthalmitis treatment with antibiotics associated or not with pars plana vitrectomy: a randomized clinical trial Open
View article: Postoperative endophthalmitis treatment with antibiotics associated or not with pars plana vitrectomy: a randomized clinical trial
Postoperative endophthalmitis treatment with antibiotics associated or not with pars plana vitrectomy: a randomized clinical trial Open
Background Postoperative endophthalmitis (PSE) is a severe ocular complication that can lead to irreversible vision loss or even globe atrophy. The Endophthalmitis Vitrectomy Study (EVS) historically guided PSE management but is increasing…
View article: Molecular Tracking of Emerging Fusarium Species in Keratitis: F. veterinarium, F. contaminatum, and F. curvatum
Molecular Tracking of Emerging Fusarium Species in Keratitis: F. veterinarium, F. contaminatum, and F. curvatum Open
View article: Intracameral voriconazole for severe fungal keratitis: a case series
Intracameral voriconazole for severe fungal keratitis: a case series Open
As an adjuvant treatment for deep fungal keratitis, intracameral voriconazole injection is a feasible option. Although fungal eradication was achieved in all patients, three required therapeutic keratoplasty and all patients had unsatisfac…
View article: A double-masked, sham-controlled trial of rose bengal photodynamic therapy for the treatment of fungal and acanthamoeba keratitis: Rose Bengal Electromagnetic Activation with Green Light for Infection Reduction (REAGIR) study
A double-masked, sham-controlled trial of rose bengal photodynamic therapy for the treatment of fungal and acanthamoeba keratitis: Rose Bengal Electromagnetic Activation with Green Light for Infection Reduction (REAGIR) study Open
Background Infectious keratitis secondary to fungus or acanthamoeba often has a poor outcome despite receiving the best available medical therapy. In vitro rose bengal photodynamic therapy (RB-PDT) appears to be effective against fungal an…
View article: Práxis extensionista e afrofuturismo
Práxis extensionista e afrofuturismo Open
O presente relato tem como objetivo apresentar os processos que resultaram na criação do Círculo de Leituras, elaborado na Região do Perobal, na zona sul da cidade de Londrina/Paraná, no ano de 2022, por estudantes e pesquisadores de curso…
View article: PRÁXIS NA PANDEMIA
PRÁXIS NA PANDEMIA Open
Este artigo teve como objetivo apresentar o desenrolar do programa “Sextou Sociológico”, resultado da disciplina “Projetos Integrados de Pesquisa, Ensino e Extensão” e dos esforços de pesquisadores do Projeto de Extensão “Práxis Itinerante…
View article: A double-masked, sham-controlled trial of rose bengal photodynamic therapy for the treatment of fungal and acanthameoba keratitis: Rose Bengal Electromagnetic Activation with Green Light for Infection Reduction (REAGIR) Study
A double-masked, sham-controlled trial of rose bengal photodynamic therapy for the treatment of fungal and acanthameoba keratitis: Rose Bengal Electromagnetic Activation with Green Light for Infection Reduction (REAGIR) Study Open
View article: Adhesion of <i>Acanthamoeba</i> on Scleral Contact Lenses According to Lens Shape
Adhesion of <i>Acanthamoeba</i> on Scleral Contact Lenses According to Lens Shape Open
The findings revealed that the curved shape of the ScCL favors amoeba adhesion.
View article: Novel amplified fragment length polymorphism (AFLP) markers for typing medically relevant Fusarium and allied fusarioid genera
Novel amplified fragment length polymorphism (AFLP) markers for typing medically relevant Fusarium and allied fusarioid genera Open
Fusariosis is an emerging mycosis caused by diverse Fusarium and allied fusarioid genera that are characterized by spindle-shaped macroconidia. These fungi possess a broad ecological distribution, causing infections in a wide diversity of …
View article: Keratitis and corneal perforation in reactive arthritis: A case report and review
Keratitis and corneal perforation in reactive arthritis: A case report and review Open
To report a rare case of corneal perforation in reactive arthritis and review the scientific basis for it. A case report. A 22-year-old male patient presented with redness, foreign body sensation, and blurred vision associated with knee an…
View article: Microbial keratitis in Sao Paulo, Brazil: a 10-year review of laboratory results, epidemiological features, and risk factors
Microbial keratitis in Sao Paulo, Brazil: a 10-year review of laboratory results, epidemiological features, and risk factors Open
Our findings demonstrated a higher positivity of corneal sample cultures for bacteria. Among those, CoNS was the most frequently identified, with S. epidermidis as the main agent. In fungal keratitis, Fusarium spp. was the most commonly is…
View article: Bacterial endophthalmitis following anti-VEGF intravitreal injections: a retrospective case series
Bacterial endophthalmitis following anti-VEGF intravitreal injections: a retrospective case series Open
Background To describe the incidence of endophthalmitis and the treatment outcomes of acute bacterial endophthalmitis following intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections in a Brazilian hospital. The analys…
View article: In Vitro Evaluation of Rose Bengal Photoactivated by Custom-Built Green Light-Emitting Diode Source for Bacteria and Rapidly Growing Mycobacteria Inhibition
In Vitro Evaluation of Rose Bengal Photoactivated by Custom-Built Green Light-Emitting Diode Source for Bacteria and Rapidly Growing Mycobacteria Inhibition Open
Validating in vitro the custom-built green LED encourages the clinical application for the treatment of infectious keratitis.
View article: Candida species causing fungal keratitis: molecular identification, antifungal susceptibility, biofilm formation, and clinical aspects
Candida species causing fungal keratitis: molecular identification, antifungal susceptibility, biofilm formation, and clinical aspects Open
View article: SARS-CoV-2 and the ocular surface: test accuracy and viral load
SARS-CoV-2 and the ocular surface: test accuracy and viral load Open
The Schirmer (16.3%) and conjunctival swab (17.4%) tests were comparably capable of detecting SARS-CoV-2 RNA in the ocular surface by RT-PCR accurately based on nasopharyngeal status and demonstrated indistinct sensitivity and specificity.…
View article: Bilateral interstitial keratitis in a patient with presumed brain tuberculoma
Bilateral interstitial keratitis in a patient with presumed brain tuberculoma Open
Interstitial keratitis is an inflammation of the corneal stroma without epithelium or endothelium involvement. The underlying causes are mostly infectious or immune mediated. Brazil has one of the highest incidence rates of tuberculosis in…
View article: Bilateral interstitial keratitis in a patient with presumed brain tuberculoma
Bilateral interstitial keratitis in a patient with presumed brain tuberculoma Open
Interstitial keratitis is an inflammation of the corneal stroma without epithelium or endothelium involvement. The underlying causes are mostly infectious or immune mediated. Brazil has one of the highest incidence rates of tuberculosis in…
View article: SARS-CoV-2 and the ocular surface: test accuracy and viral load
SARS-CoV-2 and the ocular surface: test accuracy and viral load Open
Purpose: This study aimed to evaluate the pre-sence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in the ocular surface of individuals clinically suspected of coronavirus disease 2019 (COVID-19) and determine the accu…
View article: Evaluation of the Pathogenic Potential of Escherichia coli Strains Isolated from Eye Infections
Evaluation of the Pathogenic Potential of Escherichia coli Strains Isolated from Eye Infections Open
While primarily Gram-positive bacteria cause bacterial eye infections, several Gram-negative species also pose eye health risks. Currently, few studies have tried to understand the pathogenic mechanisms involved in E. coli eye infections. …
View article: Bilateral interstitial keratitis in a patient with presumed brain tuberculoma
Bilateral interstitial keratitis in a patient with presumed brain tuberculoma Open
Interstitial keratitis is an inflammation of the corneal stroma without epithelium or endothelium involvement. The underlying causes are mostly infectious or immune mediated. Brazil has one of the highest incidence rates of tuberculosis in…
View article: Study of the corneal temperature variation during photo-refractive procedures
Study of the corneal temperature variation during photo-refractive procedures Open
View article: Fungal keratitis management in a referral cornea center in Brazil
Fungal keratitis management in a referral cornea center in Brazil Open
Purpose: To report etiological diagnosis, predisposing risk factors, therapeutic strategies and visual outcome of patients treated at the Department of Ophthalmology of Federal University of São Paulo. Methods: This is a retrospective, des…
View article: Characterization and distribution of viridans group streptococci isolated from infectious endophthalmitis and keratitis
Characterization and distribution of viridans group streptococci isolated from infectious endophthalmitis and keratitis Open
Purpose: The aims of this study were to characterize alpha-hemolytic streptococci among isolates from cases of infectious endophthalmitis and keratitis and to determine their distributions. Methods: The sample included 27 and 35 nonduplica…
View article: Three Decades of Contact Lens-associated Microbial Keratitis in a Referral Hospital in São Paulo, Brazil
Three Decades of Contact Lens-associated Microbial Keratitis in a Referral Hospital in São Paulo, Brazil Open
Females and young adults aged 19-40 years exhibited the highest frequency of contact-lens-associated microbial keratitis in our study. Staphylococcus spp. and Fusarium spp. were the predominant bacteria and fungi, respectively, isolated fr…
View article: The Role of Corneal Biomechanics for the Evaluation of Ectasia Patients
The Role of Corneal Biomechanics for the Evaluation of Ectasia Patients Open
Purpose: To review the role of corneal biomechanics for the clinical evaluation of patients with ectatic corneal diseases. Methods: A total of 1295 eyes were included for analysis in this study. The normal healthy group (group N) included …
View article: Fungal keratitis management in a referral cornea center in Brazil
Fungal keratitis management in a referral cornea center in Brazil Open
Purpose: To report etiological diagnosis, predisposing risk factors, therapeutic strategies and visual outcome of patients treated at the Department of Ophthalmology of Federal University of São Paulo. Methods: This is a retrospective, des…
View article: Caracterização e distribuição de estreptococos do grupo viridans isolados de endoftalmite infecciosa e ceratite
Caracterização e distribuição de estreptococos do grupo viridans isolados de endoftalmite infecciosa e ceratite Open
The distribution of alpha-hemolytic streptococci in ocular infections suggested the presence of a species-specific tissue tropism. The prognoses of patients with ocular streptococcal infections were highly unfavorable, and antibiotic resis…