Anand J. Kulkarni
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View article: Undergraduate medical education amidst volatility, uncertainty, complexity, ambiguity
Undergraduate medical education amidst volatility, uncertainty, complexity, ambiguity Open
Undergraduate medical education, especially in the United States, is being shaped by an environment that is changing at an unprecedented pace, creating new challenges for institutions, faculty, and students. For medical education to adapt …
View article: Snail Homing and Mating Search Algorithm for Weight Optimization of Stepped-Transmission Shaft
Snail Homing and Mating Search Algorithm for Weight Optimization of Stepped-Transmission Shaft Open
In this paper, the steeped-transmission shaft design problem is proposed for weight optimization. The bio-inspired search-based Snail Homing and Mating Search (SHMS) algorithm is utilized to solve the problem. It is inspired by the social …
View article: Fig Tree-Wasp Symbiotic Coevolutionary Optimization Algorithm
Fig Tree-Wasp Symbiotic Coevolutionary Optimization Algorithm Open
The nature inspired algorithms are becoming popular due to their simplicity and wider applicability. In the recent past several such algorithms have been developed. They are mainly bio-inspired, swarm based, physics based and socio-inspire…
View article: Fig Tree-Wasp Symbiotic Coevolutionary Optimization Algorithm
Fig Tree-Wasp Symbiotic Coevolutionary Optimization Algorithm Open
The nature inspired algorithms are becoming popular due to their simplicity and wider applicability. In the recent past several such algorithms have been developed. They are mainly bio-inspired, swarm based, physics based and socio-inspire…
View article: Hepatic Manifestations Following Gene Therapy
Hepatic Manifestations Following Gene Therapy Open
View article: A machine learning approach to predict demand-to- capacity ratio for reinforced concrete jacketing of columns in seismic-deficient buildings
A machine learning approach to predict demand-to- capacity ratio for reinforced concrete jacketing of columns in seismic-deficient buildings Open
Existing reinforced concrete (RC) buildings risk seismic damage because they were not constructed in compliance with seismic design standards and may have irregular mass distribution and construction defects. Typically, columns in these bu…
View article: Snail Homing and Mating Search Algorithm: A Novel Bio-Inspired Metaheuristic Algorithm
Snail Homing and Mating Search Algorithm: A Novel Bio-Inspired Metaheuristic Algorithm Open
In this paper, a novel Snail Homing and Mating Search (SHMS) algorithm is proposed. It is inspired from the biological behaviour of the snails. Snails continuously travels to find food and a mate, leaving behind a trail of mucus that serve…
View article: Ontology-Based Natural Language Processing for Sentimental Knowledge Analysis Using Deep Learning Architectures
Ontology-Based Natural Language Processing for Sentimental Knowledge Analysis Using Deep Learning Architectures Open
When tested with popular datasets, sentiment categorization using deep learning (DL) algorithms will produce positive results. Building a corpus on novel themes to train machine learning methods in sentiment classification with high assura…
View article: Integration of sensors through additive manufacturing leading to increased efficiencies of gas turbines for power generation and propulsion
Integration of sensors through additive manufacturing leading to increased efficiencies of gas turbines for power generation and propulsion Open
To realize the full capability of additively manufactured components in complex energy systems, it is imperative to minimize early component failures during development phases and during operation. Traditional field feedback timelines and …
View article: Review of: "Optimized Material Removal and Tool Wear Rates in Milling API 5ST TS-90 Alloy: AI-Driven Optimization and Modelling with ANN, ANFIS, and RSM"
Review of: "Optimized Material Removal and Tool Wear Rates in Milling API 5ST TS-90 Alloy: AI-Driven Optimization and Modelling with ANN, ANFIS, and RSM" Open
The work proposed in the manuscript seems quite sound; however, there is one section is required to be added discussing the significance of the work. I suggest to be concise and clear in the addressing the limitations of the work as well.
View article: Solution to Advanced Manufacturing Process Problems using Cohort Intelligence Algorithm with Improved Constraint Handling Approaches
Solution to Advanced Manufacturing Process Problems using Cohort Intelligence Algorithm with Improved Constraint Handling Approaches Open
Recently, various Artificial Intelligence (AI) based optimization metaheuristics are proposed and applied for a variety of problems. Cohort Intelligence (CI) algorithm is a socio inspired optimization technique which is successfully applie…
View article: Snail Homing and Mating Search Algorithm: A Novel Bio-Inspired Metaheuristic Algorithm
Snail Homing and Mating Search Algorithm: A Novel Bio-Inspired Metaheuristic Algorithm Open
In this paper, a novel Snail Homing and Mating Search (SHMS) algorithm is proposed. It is inspired from the biological behaviour of the snails. Snails continuously travels to find food and a mate, leaving behind a trail of mucus that serve…
View article: Modified LAB Algorithm with Clustering-based Search Space Reduction Method for solving Engineering Design Problems
Modified LAB Algorithm with Clustering-based Search Space Reduction Method for solving Engineering Design Problems Open
A modified LAB algorithm is introduced in this paper. It builds upon the original LAB algorithm (Reddy et al. 2023), which is a socio-inspired algorithm that models competitive and learning behaviours within a group, establishing hierarchi…
View article: Global disparities in mortality and liver transplantation in hospitalised patients with cirrhosis: a prospective cohort study for the CLEARED Consortium
Global disparities in mortality and liver transplantation in hospitalised patients with cirrhosis: a prospective cohort study for the CLEARED Consortium Open
View article: Supplementary Methods from Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth
Supplementary Methods from Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth Open
Supplementary Methods - PDF file 62K, Additional methods to support the manuscript 1. Cloning and protein purification 2. AKR1C3 enzyme activity and thin layer chromatography (TLC)
View article: Data from Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth
Data from Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth Open
Purpose: Castration-resistant prostate cancer (CRPC) may occur by several mechanisms including the upregulation of androgen receptor (AR), coactivators, and steroidogenic enzymes, including aldo keto reductase 1C3 (AKR1C3). AKR1C3 c…
View article: Data from Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth
Data from Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth Open
Purpose: Castration-resistant prostate cancer (CRPC) may occur by several mechanisms including the upregulation of androgen receptor (AR), coactivators, and steroidogenic enzymes, including aldo keto reductase 1C3 (AKR1C3). AKR1C3 c…
View article: Supplementary Figures and Tables from Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth
Supplementary Figures and Tables from Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth Open
Supplementary Figures and Tables - PDF file 898K, Supplementary Table ST1: AKR1C3 over-expression in HEK-293 cells reduces IC50 of androgens. Supplementary Table ST2: Finasteride increases the testosterone formation. Supplementary Figure S…
View article: Supplementary Figures and Tables from Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth
Supplementary Figures and Tables from Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth Open
Supplementary Figures and Tables - PDF file 898K, Supplementary Table ST1: AKR1C3 over-expression in HEK-293 cells reduces IC50 of androgens. Supplementary Table ST2: Finasteride increases the testosterone formation. Supplementary Figure S…
View article: Supplementary Methods from Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth
Supplementary Methods from Steroidogenic Enzyme AKR1C3 Is a Novel Androgen Receptor-Selective Coactivator that Promotes Prostate Cancer Growth Open
Supplementary Methods - PDF file 62K, Additional methods to support the manuscript 1. Cloning and protein purification 2. AKR1C3 enzyme activity and thin layer chromatography (TLC)
View article: O-25 ASSESSMENT OF MODELS FOR PREDICTING RESPONSE TO CORTICOIDS TREATMENT IN ALCOHOL-ASSOCIATED HEPATITIS: A GLOBAL COHORT STUDY
O-25 ASSESSMENT OF MODELS FOR PREDICTING RESPONSE TO CORTICOIDS TREATMENT IN ALCOHOL-ASSOCIATED HEPATITIS: A GLOBAL COHORT STUDY Open
Introduction and Objectives: Alcohol-associated hepatitis (AH) is a severe entity associated with high mortality. Corticosteroids might be used in cases with severe disease and several dynamic models can predict mortality and response to c…
View article: LAB: A Leader-Advocate-Believer Based Optimization Algorithm
LAB: A Leader-Advocate-Believer Based Optimization Algorithm Open
This manuscript introduces a new socio-inspired metaheuristic technique referred to as Leader-Advocate-Believer based optimization algorithm (LAB) for engineering and global optimization problems. The proposed algorithm is inspired by the …
View article: Improving the perioperative pathway of patients with diabetes undergoing surgery – a quality improvement project
Improving the perioperative pathway of patients with diabetes undergoing surgery – a quality improvement project Open
View article: A socio-physics based hybrid metaheuristic for solving complex non-convex constrained optimization problems
A socio-physics based hybrid metaheuristic for solving complex non-convex constrained optimization problems Open
Several Artificial Intelligence based heuristic and metaheuristic algorithms have been developed so far. These algorithms have shown their superiority towards solving complex problems from different domains. However, it is necessary to cri…
View article: A socio-physics based hybrid metaheuristic for solving complex non-convex constrained optimization problems
A socio-physics based hybrid metaheuristic for solving complex non-convex constrained optimization problems Open
Several Artificial Intelligence based heuristic and metaheuristic algorithms have been developed so far. These algorithms have shown their superiority towards solving complex problems from different domains. However, it is necessary to cri…
View article: COVID-19 vaccine induced autoimmune hepatitis-a first case series from India
COVID-19 vaccine induced autoimmune hepatitis-a first case series from India Open
View article: Patients with decompensated cirrhosis and liver transplant recipients demonstrate poor humoral and cellular immune response against COVID-19 vaccine
Patients with decompensated cirrhosis and liver transplant recipients demonstrate poor humoral and cellular immune response against COVID-19 vaccine Open
View article: LAB: A Leader-Advocate-Believer Based Optimization Algorithm
LAB: A Leader-Advocate-Believer Based Optimization Algorithm Open
This manuscript introduces a new socio-inspired metaheuristic technique referred to as Leader-Advocate-Believer based optimization algorithm (LAB) for engineering and global optimization problems. The proposed algorithm is inspired by the …
View article: Africa's Knowledge Economy and Links to India
Africa's Knowledge Economy and Links to India Open
Competitive advantage for economies, both developed and developing, will be increasingly based on knowledge in all its forms, including science and technology, smart entrepreneurship, and new business and organizational development models.…
View article: Food addiction in NAFLD and Obesity: a component of behaviour
Food addiction in NAFLD and Obesity: a component of behaviour Open