K. S. Sri Vijay Anand
YOU?
Author Swipe
View article: The Association of Modic Changes and Disc-Endplate-Bone Marrow Complex Classification in Patients With Cervical Degenerative Disc Disease
The Association of Modic Changes and Disc-Endplate-Bone Marrow Complex Classification in Patients With Cervical Degenerative Disc Disease Open
Study design Observational cohort study. Objective To assess the association of Modic changes and DEBC classification in patients with cervical degenerative disc disease. Methods The study includes 2 groups, neck pain patients presenting t…
View article: Role of Magnetic Resonance Spectroscopy and T2 Relaxometry as Imaging Biomarker of Early Lumbar Intervertebral Disc Degeneration
Role of Magnetic Resonance Spectroscopy and T2 Relaxometry as Imaging Biomarker of Early Lumbar Intervertebral Disc Degeneration Open
Study Design Observational comparative study. Objective To study the role of magnetic resonance spectroscopy (MRS) and T2 relaxometry (T2r) as imaging biomarkers for identifying early lumbar disc degeneration. Methods We evaluated 236 disc…
View article: From Modic to Disc Endplate Bone Marrow Complex - The Natural Course and Clinical Implication of Vertebral Endplate Changes
From Modic to Disc Endplate Bone Marrow Complex - The Natural Course and Clinical Implication of Vertebral Endplate Changes Open
Study Design Review article. Objectives A review of literature on the epidemiology, natural course, pathobiology and clinical implications of vertebral endplate changes. Methods A literature search was performed using the Cochrane Database…
View article: Propensity matched outcome analysis following microdiscectomy versus interlaminar endoscopic discectomy for L5-S1 disc herniation
Propensity matched outcome analysis following microdiscectomy versus interlaminar endoscopic discectomy for L5-S1 disc herniation Open
View article: C7 distal fixation anchor and its influence on sagittal profile in posterior cervical fusion; a retrospective analysis of 44 cases
C7 distal fixation anchor and its influence on sagittal profile in posterior cervical fusion; a retrospective analysis of 44 cases Open
View article: Comparative metagenomic analysis of human intervertebral disc nucleus pulposus and cartilaginous end plates
Comparative metagenomic analysis of human intervertebral disc nucleus pulposus and cartilaginous end plates Open
Study design The diversity of microflora inhabiting endplate (EP) and nucleus pulposus (NP) tissues of human intervertebral disc (IVD) was profiled through NGS-supported 16S rRNA amplicon sequencing. Sixteen EP and their corresponding NP w…
View article: In Vertebral Hemangiomas with Neurological Deficit, Is a Less Extensive Approach Adequate
In Vertebral Hemangiomas with Neurological Deficit, Is a Less Extensive Approach Adequate Open
Study Design: This was a retrospective study.Purpose: To analyze the surgical and neurological outcomes following surgical decompression in patients with aggressive vertebral hemangioma (AVH) presenting with neurological deficit and to det…
View article: Shift of Cervical Vaccine Regime: 3-2-1
Shift of Cervical Vaccine Regime: 3-2-1 Open
View article: Novel Biomarkers of Health and Degeneration in Human Intervertebral Discs: In-depth Proteomic Analysis of Collagen Framework of Fetal, Healthy, Scoliotic, Degenerate, and Herniated Discs
Novel Biomarkers of Health and Degeneration in Human Intervertebral Discs: In-depth Proteomic Analysis of Collagen Framework of Fetal, Healthy, Scoliotic, Degenerate, and Herniated Discs Open
Study Design: Profiling proteins expressed in the nucleus pulposus (NP) of intervertebral discs (IVDs) in five different biological states.Purpose: To evaluate the molecular complexity of the collagen (COL) framework and its role in the he…
View article: Approach and Considerations for Surgery in Subaxial Cervical Spine Injury
Approach and Considerations for Surgery in Subaxial Cervical Spine Injury Open
Subaxial cervical spine injuries are common and encompass a spectrum of injuries ranging from a minor ligamentous sprain to fracture dislocation with spinal cord injury. These injuries are often missed in the initial evaluation, and a high…
View article: Influence of endplate avulsion and Modic changes on the inflammation profile of herniated discs: a proteomic and bioinformatic approach
Influence of endplate avulsion and Modic changes on the inflammation profile of herniated discs: a proteomic and bioinformatic approach Open
View article: Profiling extra cellular matrix associated proteome of human fetal nucleus pulposus in search for regenerative targets
Profiling extra cellular matrix associated proteome of human fetal nucleus pulposus in search for regenerative targets Open
Degeneration of the intervertebral disc is associated with a decrease in extra-cellular matrix (ECM) content due to an imbalance in anabolic and catabolic signaling. Our previous study profiled the core matrisome of fetal NP’s and identifi…
View article: Modic changes are associated with activation of intense inflammatory and host defense response pathways – molecular insights from proteomic analysis of human intervertebral discs
Modic changes are associated with activation of intense inflammatory and host defense response pathways – molecular insights from proteomic analysis of human intervertebral discs Open
View article: Lumbar Disc Herniation and Preoperative Modic Changes: A Prospective Analysis of the Clinical Outcomes After Microdiscectomy
Lumbar Disc Herniation and Preoperative Modic Changes: A Prospective Analysis of the Clinical Outcomes After Microdiscectomy Open
Study design: Prospective comparative cohort study. Objectives: The study aims to elucidate the relationship between Modic endplate changes and clinical outcomes after a lumbar microdiscectomy. Methods: Consecutive patients undergoing micr…
View article: Spondylolysis and Pars Repair Technique
Spondylolysis and Pars Repair Technique Open
Spondylolysis is an important cause of low back pain in children and adolescents, especially in those involved in athletic activities. Spondylolysis is caused either by a fracture or by a defect in the pars inter-articularis and can be uni…
View article: Posterior Stabilization of Unstable Sacral Fractures: A Single-Center Experience of Percutaneous Sacroiliac Screw and Lumbopelvic Fixation in 67 Cases
Posterior Stabilization of Unstable Sacral Fractures: A Single-Center Experience of Percutaneous Sacroiliac Screw and Lumbopelvic Fixation in 67 Cases Open
Study Design: This is a retrospective study.Purpose: Recent advances in intraoperative imaging and closed reduction techniques have led to a shifting trend toward surgical management in every unstable sacral fracture. This study aimed to e…
View article: Part 1: profiling extra cellular matrix core proteome of human fetal nucleus pulposus in search for regenerative targets
Part 1: profiling extra cellular matrix core proteome of human fetal nucleus pulposus in search for regenerative targets Open
View article: Can Scoliotic Discs Be Controls for Molecular Studies in Intervertebral Disc Research? Insights From Proteomics
Can Scoliotic Discs Be Controls for Molecular Studies in Intervertebral Disc Research? Insights From Proteomics Open
Study Design: Proteomic analysis of human intervertebral discs. Objectives: To compare the characters of scoliotic discs and discs from magnetic resonance imaging (MRI)–normal voluntary organ donors controls used in disc research employing…
View article: A Rare Clinical Presentation of HIV Infection
A Rare Clinical Presentation of HIV Infection Open
We report a case of a 32-year-old female who presented with neck pain followed by weakness of all four limbs for five days. She had neck pain with electric shock like sensation running down the spine on flexing the neck. She developed weak…
View article: Impact of Patient Counseling and Socioeconomic Factors on Initiation of Rehabilitation Program in Spinal Cord Injury Patients Presenting to a Tertiary Spine Unit in India
Impact of Patient Counseling and Socioeconomic Factors on Initiation of Rehabilitation Program in Spinal Cord Injury Patients Presenting to a Tertiary Spine Unit in India Open
Study Design: Prospective case series. Purpose: This study aimed to investigate the impact of education, financial income, occupation, and patient counseling on the timing of enrolment in a spinal cord injury (SCI) rehabilitation program. …
View article: Proteomic Signatures of Healthy Intervertebral Discs From Organ Donors: A Comparison With Previous Studies on Discs From Scoliosis, Animals, and Trauma
Proteomic Signatures of Healthy Intervertebral Discs From Organ Donors: A Comparison With Previous Studies on Discs From Scoliosis, Animals, and Trauma Open
The proteome of "healthy" human IVDs has been defined, and our results show that proteomic data on IVDs obtained from scoliosis, fracture patients, and cadavers lack normal physiological conditions and should not be used as biological cont…
View article: Proteomic Signature of Nucleus Pulposus in Fetal Intervertebral Disc
Proteomic Signature of Nucleus Pulposus in Fetal Intervertebral Disc Open
Study Design: Profiling proteins expressed in the nucleus pulposus of fetal intervertebral disc (IVD).Purpose: To evaluate the molecular complexity of fetal IVDs not exposed to mechanical, traumatic, inflammatory, or infective insults to g…
View article: Subclinical Infection and Disc Dysbiosis as a Cause of Degenerative Disc Disease and Low Back Pain
Subclinical Infection and Disc Dysbiosis as a Cause of Degenerative Disc Disease and Low Back Pain Open
View article: Does Sarcopenia Increase the Risk for Fresh Vertebral Fragility Fractures?: A Case-Control Study
Does Sarcopenia Increase the Risk for Fresh Vertebral Fragility Fractures?: A Case-Control Study Open
Sarcopenia is not an independent risk factor for fresh vertebral fragility fractures in the elderly.