Anandie le Roux
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View article: In vitro inhibition of snake venom toxins by varespladib, marimastat, nafamostat and dimercaprol
In vitro inhibition of snake venom toxins by varespladib, marimastat, nafamostat and dimercaprol Open
Snakebite envenoming causes more than 130,000 deaths and more than 400,000 disabilities per year and has been classified as a priority Neglected Tropical Disease by the World Health Organization (WHO). While antivenom therapy remains the m…
View article: An investigation of the monoamine oxidase inhibition properties of benzothiazole derivatives
An investigation of the monoamine oxidase inhibition properties of benzothiazole derivatives Open
Literature reports that alkyloxy substituted coumarin derivatives inhibit the monoamine oxidase (MAO) enzymes, specifically the MAO-B isoform. To further investigate this finding, the present study synthesised and evaluated a series of alk…