Ananthu James
YOU?
Author Swipe
View article: Effect of indoor residual spraying on sandfly abundance and incidence of visceral leishmaniasis in India, 2016–22: an interrupted time-series analysis and modelling study
Effect of indoor residual spraying on sandfly abundance and incidence of visceral leishmaniasis in India, 2016–22: an interrupted time-series analysis and modelling study Open
View article: Predictive Value of Microfilariae-Based Stop-MDA Thresholds After Triple Drug Therapy With IDA Against Lymphatic Filariasis in Treatment-Naive Indian Settings
Predictive Value of Microfilariae-Based Stop-MDA Thresholds After Triple Drug Therapy With IDA Against Lymphatic Filariasis in Treatment-Naive Indian Settings Open
Mass drug administration (MDA) of antifilarial drugs is the main strategy for the elimination of lymphatic filariasis (LF). Recent clinical trials indicated that the triple-drug therapy with ivermectin, diethylcarbamazine, and albendazole …
View article: Accelerating Progress Towards the 2030 Neglected Tropical Diseases Targets: How Can Quantitative Modeling Support Programmatic Decisions?
Accelerating Progress Towards the 2030 Neglected Tropical Diseases Targets: How Can Quantitative Modeling Support Programmatic Decisions? Open
Over the past decade, considerable progress has been made in the control, elimination, and eradication of neglected tropical diseases (NTDs). Despite these advances, most NTD programs have recently experienced important setbacks; for examp…
View article: Elimination of transmission of onchocerciasis (river blindness) with long-term ivermectin mass drug administration with or without vector control in sub-Saharan Africa: a systematic review and meta-analysis
Elimination of transmission of onchocerciasis (river blindness) with long-term ivermectin mass drug administration with or without vector control in sub-Saharan Africa: a systematic review and meta-analysis Open
For the Swahili, French, Spanish and Portuguese translations of the abstract see Supplementary Materials section.
View article: Links across disabilities: unveiling associations between functional domains
Links across disabilities: unveiling associations between functional domains Open
Background Persons with disabilities experience higher risks of mortality as well as poorer health as compared to the general population. The aim of this study is to estimate the correlations between functional difficulties across several …
View article: The Impact of Indoor Residual Spraying on Sandfly Abundance and Incidence of Visceral Leishmaniasis in India from 2016 to 2022
The Impact of Indoor Residual Spraying on Sandfly Abundance and Incidence of Visceral Leishmaniasis in India from 2016 to 2022 Open
View article: Asymptomatic SARS-CoV-2 infections tend to occur less frequently in developed nations
Asymptomatic SARS-CoV-2 infections tend to occur less frequently in developed nations Open
Unlike severe infections, asymptomatic infections occur independently of healthcare access and reflect the natural immunity to SARS-CoV-2. What determines their prevalence, ψ , and its variation across nations is unknown. We conducted a sy…
View article: The predictive value of microfilariae-based stop-MDA thresholds after triple drug therapy with IDA in treatment-naive Indian settings
The predictive value of microfilariae-based stop-MDA thresholds after triple drug therapy with IDA in treatment-naive Indian settings Open
Mass drug administration (MDA) of antifilarial drugs is the main strategy towards the elimination of lymphatic filariasis (LF). Recent clinical trials indicated that the triple drug therapy with ivermectin, diethylcarbamazine and albendazo…
View article: A Platform for Data-Centric, Continuous Epidemiological Analyses (EpiGraphHub): Descriptive Analysis
A Platform for Data-Centric, Continuous Epidemiological Analyses (EpiGraphHub): Descriptive Analysis Open
Background Guaranteeing durability, provenance, accessibility, and trust in open data sets can be challenging for researchers and organizations that rely on public repositories of data critical for epidemiology and other health analytics. …
View article: Elimination of Transmission of Onchocerciasis with Long-Term Ivermectin Mass Drug Administration with or Without Vector Control in Sub-Saharan Africa: A Systematic Review and Meta-Analysis
Elimination of Transmission of Onchocerciasis with Long-Term Ivermectin Mass Drug Administration with or Without Vector Control in Sub-Saharan Africa: A Systematic Review and Meta-Analysis Open
View article: A Platform for Data-Centric, Continuous Epidemiological Analyses (EpiGraphHub): Descriptive Analysis (Preprint)
A Platform for Data-Centric, Continuous Epidemiological Analyses (EpiGraphHub): Descriptive Analysis (Preprint) Open
BACKGROUND Guaranteeing durability, provenance, accessibility, and trust in open data sets can be challenging for researchers and organizations that rely on public repositories of data critical for epidemiology and other health analytics.…
View article: Leveraging human resources for outbreak analysis: lessons from an international collaboration to support the sub-Saharan African COVID-19 response
Leveraging human resources for outbreak analysis: lessons from an international collaboration to support the sub-Saharan African COVID-19 response Open
View article: A Platform for Data-centric, Continuous Epidemiological Analyses
A Platform for Data-centric, Continuous Epidemiological Analyses Open
Guaranteeing durability, provenance, accessibility, and trust in open datasets can be challenging for researchers and organizations that rely on public repositories of data critical to epidemiology and other health analytics. Not only are …
View article: An in-depth statistical analysis of the COVID-19 pandemic’s initial spread in the WHO African region
An in-depth statistical analysis of the COVID-19 pandemic’s initial spread in the WHO African region Open
During the first wave of the COVID-19 pandemic, sub-Saharan African countries experienced comparatively lower rates of SARS-CoV-2 infections and related deaths than in other parts of the world, the reasons for which remain unclear. Yet, th…
View article: Transmitted HIV-1 is more virulent in heterosexual individuals than men-who-have-sex-with-men
Transmitted HIV-1 is more virulent in heterosexual individuals than men-who-have-sex-with-men Open
Transmission bottlenecks introduce selection pressures on HIV-1 that vary with the mode of transmission. Recent studies on small cohorts have suggested that stronger selection pressures lead to fitter transmitted/founder (T/F) strains. Man…
View article: COVID-19 pandemic in Africa’s island nations during the first 9 months: a descriptive study of variation in patterns of infection, severe disease, and response measures
COVID-19 pandemic in Africa’s island nations during the first 9 months: a descriptive study of variation in patterns of infection, severe disease, and response measures Open
The geographic and economic characteristics unique to island nations create a different set of conditions for, and responses to, the spread of a pandemic compared with those of mainland countries. Here, we aimed to describe the initial per…
View article: COVID-19 mortality in women and men in sub-Saharan Africa: a cross-sectional study
COVID-19 mortality in women and men in sub-Saharan Africa: a cross-sectional study Open
Introduction Since sex-based biological and gender factors influence COVID-19 mortality, we wanted to investigate the difference in mortality rates between women and men in sub-Saharan Africa (SSA). Method We included 69 580 cases of COVID…
View article: An in-depth statistical analysis of the COVID-19 pandemic’s initial spread in the WHO African region
An in-depth statistical analysis of the COVID-19 pandemic’s initial spread in the WHO African region Open
During the first wave of the COVID-19 pandemic, sub-Saharan African countries experienced comparatively lower rates of SARS-CoV-2 infections and related deaths than in other parts of the world, the reasons for which remain unclear. Yet, th…
View article: COVID-19 Mortality in Women and Men in Sub-Saharan Africa: A Cross Sectional Study
COVID-19 Mortality in Women and Men in Sub-Saharan Africa: A Cross Sectional Study Open
Objective To investigate differences of COVID-19 related mortality among women and men across sub-Saharan Africa (SSA) from the beginning of the pandemic. Design A cross sectional study. Setting Data from 20 member nations of the WHO Afric…
View article: First wave of the COVID-19 pandemic in Africa’s island nations: A descriptive study of the variation in the disease burden
First wave of the COVID-19 pandemic in Africa’s island nations: A descriptive study of the variation in the disease burden Open
Motivated by the idea that island nations might respond differently to non-island countries in handling pandemic situations, we aimed to study the first wave of COVID-19, along with the potential reasons behind the variation in disease bur…
View article: Transmitted HIV-1 is more pathogenic in heterosexual individuals than homosexual men
Transmitted HIV-1 is more pathogenic in heterosexual individuals than homosexual men Open
Transmission bottlenecks introduce selection pressures on HIV-1 that vary substantially with the mode of transmission. Recent studies on small cohorts have suggested that stronger selection pressures lead to fitter transmitted/founder (T/F…
View article: Fixation probability of a nonmutator in a large population of asexual mutators
Fixation probability of a nonmutator in a large population of asexual mutators Open
View article: Fixation probability of a nonmutator in a large population of asexual\n mutators
Fixation probability of a nonmutator in a large population of asexual\n mutators Open
In an adapted population of mutators in which most mutations are deleterious,\na nonmutator that lowers the mutation rate is under indirect selection and can\nsweep to fixation. Using a multitype branching process, we calculate the\nfixati…
View article: Role of epistasis on the fixation probability of a non-mutator in an adapted asexual population
Role of epistasis on the fixation probability of a non-mutator in an adapted asexual population Open
View article: Fixation probability of rare nonmutator and evolution of mutation rates
Fixation probability of rare nonmutator and evolution of mutation rates Open
Although mutations drive the evolutionary process, the rates at which the mutations occur are themselves subject to evolutionary forces. Our purpose here is to understand the role of selection and random genetic drift in the evolution of m…
View article: Pairwise estimates of population genetic distance for mtDNA among sampling localities (Φ<sub>ST</sub>, below diagonal), and associated <i>P</i> values (above diagonal).
Pairwise estimates of population genetic distance for mtDNA among sampling localities (Φ<sub>ST</sub>, below diagonal), and associated <i>P</i> values (above diagonal). Open
SWE = Sweden; NOR = Norway; MNG = Mongolia; RUS = Russia; AK = Alaska; YT = Yukon; NT = Northwest Territories; NU = Nunavut; BC = British Columbia; AB = Alberta; SK = Saskatchewan; MB = Manitoba; ON = Ontario; QC/NL = Quebec-Labrador; MT =…
View article: Geographical distribution of mtDNA haplotypes.
Geographical distribution of mtDNA haplotypes. Open
The geographic distribution of mtDNA control region haplotypes based on frequencies observed for each region. Historic samples are presented separately and identified with a red border and red sample size number.
View article: Scenarios used in DIYABC and logistic regression.
Scenarios used in DIYABC and logistic regression. Open
Graphic representation of the four scenarios used in DIYABC and logistic regression of posterior probabilities with a recent bottleneck (20th century) for MB-ON. Please note that time is not to scale.
View article: Historic and contemporary Holarctic distribution of wolverines and sampling localities.
Historic and contemporary Holarctic distribution of wolverines and sampling localities. Open
Historic and current distribution of wolverines in Eurasia (adapted from National Geographic Society [116]) and North America (adapted from COSEWIC [115]), and sampled localities from Wilson et al. [45] - triangle; Walker et al. [15…
View article: Median-joining network.
Median-joining network. Open
Median-joining network of the mtDNA control region haplotypes for all samples combined. Haplotype size reflects relative frequency. Each branch represents one mutational step, unless otherwise noted. Black circles represent missing interme…