Anders Dalby
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The SorCS2-derived macrocycle TT-P34 drives neuroprotection in animal models of neurodegeneration Open
Mitochondria are critical for sustaining the high energy demands of neuronal activity and their dysregulation is a hallmark of neurodegeneration. Targeting pathways of neurotrophic signaling is a well-established therapeutic strategy to en…
A triple serine motif in the intracellular domain of SorCS2 impacts its cellular signaling Open
The Vps10p-domain receptors SorCS1-3 have been repeatedly associated with the development of neurological and psychiatric disorders. They have emerged as key regulators of synaptic activity and neurotrophic signaling, but the underlying mo…
A triple serine motif in the intracellular domains of sortilin-related receptors SorCS1-3 regulates neurotrophic activity Open
The Vps10p-domain receptors SorCS1-3 have been repeatedly associated with the development of neurological and psychiatric disorders. They have emerged as key regulators of synaptic activity and neurotrophic signaling, but the underlying mo…