Explanipedia

The one-year trajectories of patient-reported outcomes are better for medial unicompartmental knee arthroplasty compared with total knee arthroplasty Open

Anne Louise Elkjær Christensen, Christian Bredgaard Jensen, Cecilie Henkel, Lina Holm Ingelsrud, Kristine Ifigenia Bunyoz , et al. · 2025

Aims Whether medial unicompartmental knee arthroplasty (mUKA) or total knee arthroplasty (TKA) are more suitable for patients with anteromedial osteoarthritis (AMOA) remains debated. We aimed to compare the development over time in patient…

Feasibility of a randomized trial comparing exercise-based rehabilitation to no exercise-based rehabilitation after total knee arthroplasty: DRAW-TKA hybrid 1 RCT Open

Birk Mygind Grønfeldt, Søren Thorgaard Skou, Jeanette Wassar Kirk, Anders Troelsen, Thomas Bandholm , et al. · 2025

High Reoperation Rate After Osteosynthesis of Proximal Periprosthetic Tibial Fractures Around Medial Unicompartmental Knee Arthroplasty. Open

Stefan Kastalag Risager, Anders Troelsen, Bjarke Viberg · 2025

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

Agreement between in vivo and ex vivo photon-counting CT measurements of subchondral trabecular bone features in patients with knee osteoarthritis Open

Camilla Toft Nielsen, Mikael Boesen, Marius Henriksen, Janus Damm Nybing, Sophia Wiinberg Bardenfleth , et al. · 2025

Objectives The aim of this study was to compare in vivo and ex vivo Photon Counting CT (PCCT) of subchondral bone features in patients with knee osteoarthritis (KOA). Materials and methods Pre-surgery in vivo and post-surgery ex vivo PCCT …

Optimising outcomes in lateral unicompartmental knee arthroplasty: Analysing 25 years of registry data Open

Kristine Ifigenia Bunyoz, Martin Lindberg‐Larsen, Kirill Gromov, Anders Troelsen · 2025

Purpose Limited data and experience surround lateral unicompartmental knee arthroplasty (UKA), contributing to uncertainty regarding its broader application in clinical practice. To understand how to optimise lateral UKA outcomes, this stu…

Patient perspectives of using a single home-based exercise when eligible for knee replacement due to severe osteoarthritis: A qualitative interview study Open

Birk Mygind Grønfeldt, Rasmus Skov Husted, Michael Skovdal Rathleff, Anders Troelsen, Thomas Bandholm , et al. · 2025

Background Exercise therapy is recommended for patients with severe osteoarthritis (OA) who are candidates for total knee arthroplasty (TKA). How this patient group perceives and experiences a simplified approach to pre-surgical exercise (…

Association of socioeconomic inequality and risk of periprosthetic joint infection after total knee arthroplasty: a Danish cohort study of 75,141 cases Open

Marie Anneberg, Anders Troelsen, Per Hviid Gundtoft, Alma B Pedersen · 2025

Background and purpose: Awareness of socioeconomic disparities in outcomes following surgical procedures is increasing. This highlights a critical challenge for clinical practice and public health. We examined whether low socioeconomic pos…

Anchor questions to improve patient-reported outcome measure interpretability in patients undergoing knee or hip arthroplasty - a mixed-methods content validity, construct validity, and reliability study Open

Lasse K. Harris, Trine Schifter Larsen, Berend Terluin, Henrik Hein Lauridsen, Anders Troelsen , et al. · 2025

Validation of Natural Language Processing for Surgical Complication Surveillance: Detecting Eleven Postoperative Complications from Electronic Health Records Open

Emilie Even Dencker, Alexander Bonde, Anders Troelsen, Martin Sillesen · 2025

Background Postoperative complications (PCs) rates are crucial quality metrics in surgery, as they reflect both patient outcomes, perioperative care effectiveness and healthcare resource strain. Despite their importance, efficient, accurat…

Changing the narrative for exercise-based prehabilitation: Evidence-informed and shared decision making when discussing the need for a total knee arthroplasty with patients Open

Thomas Bandholm, Rasmus Skov Husted, Anders Troelsen, Kristian Thorborg · 2025

Changing the narrative for exercise-based prehabilitation: evidence-informed and shared decision making when discussing the need for a total knee arthroplasty with patients Open

Thomas Bandholm, Rasmus Skov Husted, Anders Troelsen, Kristian Thorborg · 2025

Objective: To examine a novel application of exercise-based prehabilitation in severe knee osteoarthritis—termed "pre-evaluation exercise"—focused on supporting surgical decision-making and adherence to clinical guidelines, rather than att…

Patient-reported outcomes and complications of a new-generation total knee system: a randomized controlled trial Open

Kristian R. L. Mortensen, Lina Holm Ingelsrud, Anders Odgaard, Andreas Kappel, Claus Varnum , et al. · 2025

Background and purpose: Documentation of new-generation implants’ short-term performance could reassure surgeons and patients about their use, while awaiting the long-term outcome. Our aim was to compare the performance of a newer total kn…

Association of patellofemoral osteoarthritis on patient-reported outcomes after medial unicompartmental knee arthroplasty: a retrospective cohort study Open

Jaxon Olsen, Christian Bredgaard Jensen, Kristine Ifigenia Bunyoz, Anders Bagge, Kirill Gromov , et al. · 2025

Background and purpose: In contemporary medial unicompartmental knee arthroplasty (mUKA), non-lateral patellofemoral osteoarthritis (PFOA) is not considered a contraindication. However, we still lack knowledge on the association of PFOA se…

Characteristics of eligible patients with knee osteoarthritis accepting versus declining participation in a randomised trial investigating the effect of weight loss versus knee arthroplasty to explore generalisability: A cross‐sectional study Open

Saber Muthanna Saber Aljuboori, Robin Christensen, Marius Henriksen, Henning Bliddal, Anders Troelsen , et al. · 2025

Background The INtensive diet versus Knee Arthroplasty (INKA) trial is a randomised trial assessing weight loss as an alternative to knee arthroplasty (KA) in obese patients with severe knee osteoarthritis (OA) awaiting KA (NCT05172843). T…

2 Treatment of knee osteoarthritis with autologous micro-fragmented adipose tissue is not superior to placebo saline. An RCT with 2-year follow-up Open

Kristoffer Weisskirchner Barfod, Lars Blønd, Rasmus Kramer Mikkelsen, Jasmin Bagge, Lisbet Rosenkrantz Hölmich , et al. · 2025

Does a medial congruent bearing in total knee arthroplasty compromise fixation? A randomized controlled trial Open

Kristian R. L. Mortensen, Lina Holm Ingelsrud, Omar Muharemovic, Kirill Gromov, Anders Troelsen · 2024

We found no compromising of tibia implant fixation in TKA by choosing an MC bearing, when compared with a CR bearing. PROMs and complication rates suggest comparable treatment results with both types of bearings in TKA.

Assessing the accuracy gap in early postoperative complication surveillance: ICD-10 codes versus manual curation—clinical and economic implications Open

Emilie Even Dencker, Alexander Bonde, Stephan Sloth Lorenzen, Anders Troelsen, Martin Sillesen · 2024

Background and objective: Assessing surgical outcomes, notably postoperative complications (PCs), is crucial for healthcare systems. However, reliance on International Classification of Diseases, 10th revision (ICD-10) codes, may be subopt…

Indications for lateral unicompartmental knee arthroplasty – A systematic review Open

Kristine Ifigenia Bunyoz, Anders Troelsen, Kirill Gromov, Abtin Alvand, Nicholas Bottomley , et al. · 2024

While the literature suggests that some agreement does exist regarding indications for lateral UKA, a strong consensus was not found, indicating that well-defined and consensus-based indications for lateral UKA do not yet exist.

Patients Have Acceptable Patient-Reported Outcome Measures After Medial Unicompartmental Knee Arthroplasty Regardless of Age Open

Anders Bagge, Christian Bredgaard Jensen, Christian Skovgaard Nielsen, Kirill Gromov, Anders Troelsen · 2024

We found good patient-reported outcome measures improvements and satisfactory outcomes after mUKA in all age groups; however, patients aged 55 to < 65 years had worse changes in FJS and APQ. Results support contemporary indications for mUK…

Artificial intelligence tools trained on human-labeled data reflect human biases: a case study in a large clinical consecutive knee osteoarthritis cohort Open

Anders Lenskjold, Mathias W. Brejnebøl, Martin Høyer Rose, Henrik Gudbergsen, Akshay Chaudhari , et al. · 2024

Anteromedial knee osteoarthritis (AMOA) evaluated with magnetic resonance imaging (MRI): a cohort study of 100 patients Open

Kristine Ifigenia Bunyoz, Joseph L. Dixon, Jaison Patel, Anders Troelsen, Abtin Alvand , et al. · 2024

Introduction Magnetic resonance imaging (MRI) scans are increasingly used for knee osteoarthritis evaluation and preoperative planning before unicompartmental knee arthroplasty (UKA), and often patients already have MRI scans before their …

Starting up a Lateral Unicompartmental Knee Arthroplasty Practice – Is Outcome Affected? Open

Kristine Ifigenia Bunyoz, Kirill Gromov, Anders Troelsen · 2024

Starting up a lateral UKA practice is safe and efficient for surgeons who have prior medial UKA experience, provided strict adherence to indications. While surgical duration indicated a learning curve over approximately 33 cases, PROMs rem…

Enhancing the data capture of periprosthetic joint infections in the Danish Knee Arthroplasty Registry: validity assessment and incidence estimation Open

Marie Anneberg, Eskild Bendix Kristiansen, Anders Troelsen, Per Hviid Gundtoft, Henrik Toft Sørensen , et al. · 2024

Background and purpose: Revisions due to periprosthetic joint infection (PJI) are underestimated in national arthroplasty registries. Our primary objective was to assess the validity in the Danish Knee Arthroplasty Register (DKR) of revisi…

Postoperative orthostatic intolerance following fast-track unicompartmental knee arthroplasty: incidence and hemodynamics—a prospective observational cohort study Open

Ana‐Marija Hristovska, Louise B. Andersen, Bodil Uldall-Hansen, Henrik Kehlet, Anders Troelsen , et al. · 2024

Minimal important change thresholds change over time after knee and hip arthroplasty Open

Lasse K. Harris, Anders Troelsen, Berend Terluin, Kirill Gromov, Lina Holm Ingelsrud · 2024

Any absence of deterioration in pain and function is considered important at 3 months after knee or hip arthroplasty. Increasing thresholds over time suggest patients raise their standards for what constitutes a minimal important improveme…

Assessing the utility of natural language processing for detecting postoperative complications from free medical text Open

Emilie Even Dencker, Alexander Bonde, Anders Troelsen, Martin Sillesen · 2024

Background Postoperative complication rates are often assessed through administrative data, although this method has proven to be imprecise. Recently, new developments in natural language processing have shown promise in detecting specific…

Half of all hip and knee arthroplasty patients may be potential day-case candidates: a nationwide register study of 166,730 procedures Open

Christian Bredgaard Jensen, Anders Troelsen, Nicolai Bang Foss, Christian Skovgaard Nielsen, Martin Lindberg‐Larsen , et al. · 2024

Background and purpose: The overall potential pool of day-case candidates on a national level in hip and knee arthroplasty is unknown. We aimed to estimate the proportion of hip and knee arthroplasty patients eligible for day-case surgery …

”Pain without loosening”-revisions of knee arthroplasties in the Danish Knee Arthroplasty Register Open

Kristine Bollerup Arndt, Henrik M. Schrøder, Anders Troelsen, Mikkel Rathsach Andersen, L. Rasmussen , et al. · 2024

”Pain without loosening”-revisions of knee arthroplasties in the Danish Knee Arthroplasty Register INTRODUCTION. We aimed to investigate “pain without loosening” as an indication for knee arthroplasty revisions and to screen for other indi…

Assessing the utility of deep neural networks in detecting superficial surgical site infections from free text electronic health record data Open

Alexander Bonde, Stephan Sloth Lorenzen, Gustav Brixen, Anders Troelsen, Martin Sillesen · 2024

Background High-quality outcomes data is crucial for continued surgical quality improvement. Outcomes are generally captured through structured administrative data or through manual curation of unstructured electronic health record (EHR) d…

Does a Medial Congruent Bearing in Total Knee Arthroplasty Compromise Fixation? A Randomized Controlled Trial Open

Kristian R. L. Mortensen, Lina Holm Ingelsrud, Omar Muharemovic, Kirill Gromov, Anders Troelsen · 2024

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