Marlon Osorio
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View article: Valorization of Fique Lignocellulosic Residues for Sustainable Craft Paper Production
Valorization of Fique Lignocellulosic Residues for Sustainable Craft Paper Production Open
This paper presents the development of handmade paper from fique residues, evaluating its technical and environmental viability through a scientific approach aimed at supporting low-income rural communities. The residues were characterized…
View article: Oral dosage forms for drug delivery to the colon: an existing gap between research and commercial applications
Oral dosage forms for drug delivery to the colon: an existing gap between research and commercial applications Open
Oral drug administration is the preferred route for pharmaceuticals, accounting for ~90% of the global pharmaceutical market due to its convenience and cost-effectiveness. This study provides a comprehensive scientific and technological an…
View article: Encapsulation of a 5FU-curcumin hybrid on bacterial nanocellulose for colorectal cancer treatment
Encapsulation of a 5FU-curcumin hybrid on bacterial nanocellulose for colorectal cancer treatment Open
The traditional treatment of colorectal cancer (CRC) involves a combination of chemotherapy and synthetic and natural drugs. In this study, a hybrid compound of 5-fluorouracil-curcumin encapsulated in bacterial nanocellulose (BNC) was eval…
View article: Bacterial nanocellulose spheres coated with meta acrylic copolymer: Vaccinium meridionale swartz extract delivery for colorectal cancer chemoprevention
Bacterial nanocellulose spheres coated with meta acrylic copolymer: Vaccinium meridionale swartz extract delivery for colorectal cancer chemoprevention Open
Bacterial nanocellulose, a natural hydrocolloid traditionally used as a food ingredient, has demonstrated potential as a non-soluble dietary fiber and functional material. Moreover, its properties can further be potentialized whether coupl…
View article: Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention
Mechanisms of Action of Fruit and Vegetable Phytochemicals in Colorectal Cancer Prevention Open
Colorectal cancer (CRC) is the third most common cancer worldwide and its incidence is expected to increase by almost 80% by 2030. CRC apparition is related to poor diet, mainly due to low consumption of phytochemicals present in fruits an…
View article: Biomineralization in Three-Dimensional Scaffolds Based on Bacterial Nanocellulose for Bone Tissue Engineering: Feature Characterization and Stem Cell Differentiation
Biomineralization in Three-Dimensional Scaffolds Based on Bacterial Nanocellulose for Bone Tissue Engineering: Feature Characterization and Stem Cell Differentiation Open
Bacterial nanocellulose (BNC) has a negative surface charge in physiological environments, which allows the adsorption of calcium ions to initiate the nucleation of different calcium phosphate phases. The aim of this study was to investiga…
View article: Isolation of cellulose microfibers and nanofibers by mechanical fibrillation in a water-free solvent
Isolation of cellulose microfibers and nanofibers by mechanical fibrillation in a water-free solvent Open
Cellulose from vegetable sources is the most abundant biopolymer on earth. In plants, cellulose is a reinforcement element that conforms to a hierarchical structure. Cellulose micro-/nanofibers can be isolated from the cell wall by top-dow…
View article: Biomineralization Process in Three-Dimensional Scaffolds Based on Bacterial Nanocellulose for Bone Tissue Engineering: Chemi-Cal and Morphological Features, and Stem Cell Differentiation
Biomineralization Process in Three-Dimensional Scaffolds Based on Bacterial Nanocellulose for Bone Tissue Engineering: Chemi-Cal and Morphological Features, and Stem Cell Differentiation Open
Bacterial nanocellulose (BNC) surface has a negative charge that allows the adsorption of calcium ions to initiate the nucleation of different calcium phosphate phases. The aim of this study was to investigate different methods of minerali…
View article: Advances in Tumor Organoids for the Evaluation of Drugs: A Bibliographic Review
Advances in Tumor Organoids for the Evaluation of Drugs: A Bibliographic Review Open
Tumor organoids are defined as self-organized three-dimensional assemblies of heterogeneous cell types derived from patient samples that mimic the key histopathological, genetic, and phenotypic characteristics of the original tumor. This t…
View article: Development of Genistein Drug Delivery Systems Based on Bacterial Nanocellulose for Potential Colorectal Cancer Chemoprevention: Effect of Nanocellulose Surface Modification on Genistein Adsorption
Development of Genistein Drug Delivery Systems Based on Bacterial Nanocellulose for Potential Colorectal Cancer Chemoprevention: Effect of Nanocellulose Surface Modification on Genistein Adsorption Open
Genistein is an isoflavone with antioxidant, anti-inflammatory, and anticancer properties. That said, its use in the industry is limited by its low solubility in aqueous systems. In this work, bacterial nanocellulose (BNC) and BNC modified…
View article: Evaluation of the Effects of Genistein In Vitro as a Chemopreventive Agent for Colorectal Cancer—Strategy to Improve Its Efficiency When Administered Orally
Evaluation of the Effects of Genistein In Vitro as a Chemopreventive Agent for Colorectal Cancer—Strategy to Improve Its Efficiency When Administered Orally Open
Colorectal Cancer (CRC) ranks third in terms of incidence and second in terms of mortality and prevalence worldwide. In relation to chemotherapy treatment, the most used drug is 5-fluorouracil (5-FU); however, the use of this drug generate…
View article: Assessment of Bacterial Nanocellulose Loaded with Acetylsalicylic Acid or Povidone-Iodine as Bioactive Dressings for Skin and Soft Tissue Infections
Assessment of Bacterial Nanocellulose Loaded with Acetylsalicylic Acid or Povidone-Iodine as Bioactive Dressings for Skin and Soft Tissue Infections Open
Bacterial nanocellulose (BNC) is a novel nanomaterial known for its large surface area, biocompatibility, and non-toxicity. BNC contributes to regenerative processes in the skin but lacks antimicrobial and anti-inflammatory properties. Her…
View article: Recent Advances in Polymer Nanomaterials for Drug Delivery of Adjuvants in Colorectal Cancer Treatment: A Scientific-Technological Analysis and Review
Recent Advances in Polymer Nanomaterials for Drug Delivery of Adjuvants in Colorectal Cancer Treatment: A Scientific-Technological Analysis and Review Open
Colorectal cancer (CRC) is the type with the second highest morbidity. Recently, a great number of bioactive compounds and encapsulation techniques have been developed. Thus, this paper aims to review the drug delivery strategies for chemo…
View article: Ex Vivo and In Vivo Biocompatibility Assessment (Blood and Tissue) of Three-Dimensional Bacterial Nanocellulose Biomaterials for Soft Tissue Implants
Ex Vivo and In Vivo Biocompatibility Assessment (Blood and Tissue) of Three-Dimensional Bacterial Nanocellulose Biomaterials for Soft Tissue Implants Open
Bacterial nanocellulose (BNC) is a promising biomedical material. However, the haemocompatibility (haemolysis and thrombogenicity) and acute and sub-chronic immune responses to three-dimensional (3D) BNC biomaterials have not been evaluate…
View article: Effect of Different Carbon Sources on Bacterial Nanocellulose Production and Structure Using the Low pH Resistant Strain Komagataeibacter Medellinensis
Effect of Different Carbon Sources on Bacterial Nanocellulose Production and Structure Using the Low pH Resistant Strain Komagataeibacter Medellinensis Open
Bacterial cellulose (BC) is a polymer obtained by fermentation with microorganism of different genera. Recently, new producer species have been discovered, which require identification of the most important variables affecting cellulose pr…
View article: Bioactive 3D-Shaped Wound Dressings Synthesized from Bacterial Cellulose: Effect on Cell Adhesion of Polyvinyl Alcohol Integrated In Situ
Bioactive 3D-Shaped Wound Dressings Synthesized from Bacterial Cellulose: Effect on Cell Adhesion of Polyvinyl Alcohol Integrated In Situ Open
We investigated wound dressing composites comprising fibrils of bacterial cellulose (BC) grown by fermentation in the presence of polyvinyl alcohol (PVA) followed by physical crosslinking. The reference biointerface, neat BC, favoured adhe…