András Jakab
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View article: Atlas-independent brain connectome analysis at voxel-level granularity: graph convolutional networks for etiology classification in newborns
Atlas-independent brain connectome analysis at voxel-level granularity: graph convolutional networks for etiology classification in newborns Open
Early identification of altered brain networks in neonates at risk for neurodevelopmental impairments is critical for timely intervention and improving outcomes. This study explores the potential of graph neural networks (GNNs) applied to …
View article: Lung volume segmentation in fetal MRI: super-resolution reconstructions improve inter-rater reliability
Lung volume segmentation in fetal MRI: super-resolution reconstructions improve inter-rater reliability Open
Background Fetal MRI is increasingly used to investigate fetal lung pathologies, and super-resolution (SR) algorithms could be a powerful clinical tool for this assessment. Our goal was to investigate whether SR reconstructions result in a…
View article: Constitution-Making Procedure and Legitimacy Maximisation: How Different Constitution-Making Procedures Satisfy Different Conceptions of Legitimacy
Constitution-Making Procedure and Legitimacy Maximisation: How Different Constitution-Making Procedures Satisfy Different Conceptions of Legitimacy Open
The various meanings of ‘legitimacy’ – Constitution-making procedure as a tool to achieve the right content of a new constitutional document – The effect of the procedure on the actual social and political context – Trade-offs between the …
View article: Enhancing efficiency in paediatric brain tumour segmentation using a pathologically diverse single-center clinical dataset
Enhancing efficiency in paediatric brain tumour segmentation using a pathologically diverse single-center clinical dataset Open
Background Brain tumours are the most common solid malignancies in children, encompassing diverse histological, molecular subtypes and imaging features and outcomes. Paediatric brain tumours (PBTs), including high- and low-grade gliomas (H…
View article: Placental histology, perioperative brain development, and neurodevelopmental outcome at 1 year of age in patients undergoing neonatal cardiac surgery—is there an association?
Placental histology, perioperative brain development, and neurodevelopmental outcome at 1 year of age in patients undergoing neonatal cardiac surgery—is there an association? Open
Background Patients with congenital heart disease (CHD) who are operated on after birth are at risk for neurodevelopmental (ND) impairment. Before birth, altered fetal hemodynamics due to the CHD may lead to reduced cerebral perfusion and …
View article: Atlas-independent brain connectome analysis at voxel-level granularity: graph convolutional networks for etiology classification in newborns
Atlas-independent brain connectome analysis at voxel-level granularity: graph convolutional networks for etiology classification in newborns Open
Early identification of altered brain networks in neonates at risk for neurodevelopmental impairments is critical for timely intervention and improving outcomes. This study explores the potential of graph convolutional networks (GCNs) appl…
View article: Advances in Automated Fetal Brain MRI Segmentation and Biometry: Insights from the FeTA 2024 Challenge
Advances in Automated Fetal Brain MRI Segmentation and Biometry: Insights from the FeTA 2024 Challenge Open
Accurate fetal brain tissue segmentation and biometric analysis are essential for studying brain development in utero. The FeTA Challenge 2024 advanced automated fetal brain MRI analysis by introducing biometry prediction as a new task alo…
View article: Towards contrast- and pathology-agnostic clinical fetal brain MRI segmentation using SynthSeg
Towards contrast- and pathology-agnostic clinical fetal brain MRI segmentation using SynthSeg Open
Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep learning providin…
View article: Automatic quality control in multi-centric fetal brain MRI super-resolution reconstruction
Automatic quality control in multi-centric fetal brain MRI super-resolution reconstruction Open
Quality control (QC) has long been considered essential to guarantee the reliability of neuroimaging studies. It is particularly important for fetal brain MRI, where acquisitions and image processing techniques are less standardized than i…
View article: Pathological MRI Segmentation by Synthetic Pathological Data Generation in Fetuses and Neonates
Pathological MRI Segmentation by Synthetic Pathological Data Generation in Fetuses and Neonates Open
Developing new methods for the automated analysis of clinical fetal and neonatal MRI data is limited by the scarcity of annotated pathological datasets and privacy concerns that often restrict data sharing, hindering the effectiveness of d…
View article: Six Alternatives to the Proportionality Test in Fundamental Rights Adjudication
Six Alternatives to the Proportionality Test in Fundamental Rights Adjudication Open
View article: Altered Connectome Topology in Newborns at Risk for Cognitive Developmental Delay: A Cross‐Etiologic Study
Altered Connectome Topology in Newborns at Risk for Cognitive Developmental Delay: A Cross‐Etiologic Study Open
The human brain connectome is characterized by the duality of highly modular structure and efficient integration, supporting information processing. Newborns with congenital heart disease (CHD), prematurity, or spina bifida aperta (SBA) co…
View article: The Brain Tumor Segmentation (BraTS) Challenge 2023: <i>Brain MR Image Synthesis for Tumor Segmentation (BraSyn)</i>.
The Brain Tumor Segmentation (BraTS) Challenge 2023: <i>Brain MR Image Synthesis for Tumor Segmentation (BraSyn)</i>. Open
Automated brain tumor segmentation methods have become well-established and reached performance levels offering clear clinical utility. These methods typically rely on four input magnetic resonance imaging (MRI) modalities: T1-weighted ima…
View article: Multi-Center Fetal Brain Tissue Annotation (FeTA) Challenge 2022 Results
Multi-Center Fetal Brain Tissue Annotation (FeTA) Challenge 2022 Results Open
Segmentation is a critical step in analyzing the developing human fetal brain. There have been vast improvements in automatic segmentation methods in the past several years, and the Fetal Brain Tissue Annotation (FeTA) Challenge 2021 helpe…
View article: Learning from those who thrive: protective factors and neuroimaging markers in adolescents with complex congenital heart disease and with a favorable neurodevelopmental profile
Learning from those who thrive: protective factors and neuroimaging markers in adolescents with complex congenital heart disease and with a favorable neurodevelopmental profile Open
Patients with complex congenital heart disease (cCHD) are at risk for neurodevelopmental impairments, yet many patients develop normally. This study investigated associations between a favorable neurodevelopmental profile and protective fa…
View article: Assessing Data Quality on Fetal Brain MRI Reconstruction: A Multi-site and Multi-rater Study
Assessing Data Quality on Fetal Brain MRI Reconstruction: A Multi-site and Multi-rater Study Open
View article: The cumulative impact of clinical risk on brain networks and associations with executive function impairments in adolescents with congenital heart disease
The cumulative impact of clinical risk on brain networks and associations with executive function impairments in adolescents with congenital heart disease Open
Patients with congenital heart disease (CHD) demonstrate altered structural brain network connectivity. However, there is large variability between reported results and little information is available to identify those patients at highest …
View article: OSBA: An Open Neonatal Neuroimaging Atlas and Template for Spina Bifida Aperta
OSBA: An Open Neonatal Neuroimaging Atlas and Template for Spina Bifida Aperta Open
We present the Open Spina Bifida Aperta (OSBA) atlas, an open atlas and set of neuroimaging templates for spina bifida aperta (SBA). Traditional brain atlases may not adequately capture anatomical variations present in pediatric or disease…
View article: Developmental trajectory of thalamus topography during the late preterm and perinatal period in normal development, after premature birth and in congenital heart defects
Developmental trajectory of thalamus topography during the late preterm and perinatal period in normal development, after premature birth and in congenital heart defects Open
The thalamus plays a critical role in neural circuit maturation and brain connectivity. It is well known to show a characteristic topographical organization of local and long-range connectivity, yet developmental changes in this topography…
View article: Image segmentations produced by BAMF under the AIMI Annotations initiative
Image segmentations produced by BAMF under the AIMI Annotations initiative Open
The Imaging Data Commons (IDC)(https://imaging.datacommons.cancer.gov/) [1] connects researchers with publicly available cancer imaging data, often linked with other types of cancer data. Many of the collections have limited annotations du…
View article: Prenatal assessment of brain malformations on neuroimaging: an expert panel review
Prenatal assessment of brain malformations on neuroimaging: an expert panel review Open
Brain malformations represent a heterogeneous group of abnormalities of neural morphogenesis, often associated with aberrations of neuronal connectivity and brain volume. Prenatal detection of brain malformations requires a clear understan…
View article: FetMRQC: A robust quality control system for multi-centric fetal brain MRI
FetMRQC: A robust quality control system for multi-centric fetal brain MRI Open
View article: Assessing data quality on fetal brain MRI reconstruction: a multi-site and multi-rater study⋆
Assessing data quality on fetal brain MRI reconstruction: a multi-site and multi-rater study⋆ Open
Quality assessment (QA) has long been considered essential to guarantee the reliability of neuroimaging studies. It is particularly important for fetal brain MRI, where unpredictable fetal motion can lead to substantial artifacts in the ac…
View article: Increased [18F]FDG uptake in the infarcted myocardial area displayed by combined PET/CMR correlates with snRNA-seq-detected inflammatory cell invasion
Increased [18F]FDG uptake in the infarcted myocardial area displayed by combined PET/CMR correlates with snRNA-seq-detected inflammatory cell invasion Open
View article: Altered connectome topology in newborns at risk for cognitive developmental delay: a cross-etiologic study
Altered connectome topology in newborns at risk for cognitive developmental delay: a cross-etiologic study Open
The human brain connectome is characterized by the duality of highly modular structure and efficient integration, supporting information processing. Newborns with congenital heart disease (CHD), prematurity, or spina bifida aperta (SBA) co…
View article: Inhibition abilities and functional brain connectivity in school-aged term-born and preterm-born children
Inhibition abilities and functional brain connectivity in school-aged term-born and preterm-born children Open
View article: OSBA: An open neonatal neuroimaging atlas and template for spina bifida aperta
OSBA: An open neonatal neuroimaging atlas and template for spina bifida aperta Open
We present the Open Spina Bifida Aperta (OSBA) atlas, an open atlas and set of neuroimaging templates for spina bifida aperta (SBA). Traditional brain atlases may not adequately capture anatomical variations present in pediatric or disease…
View article: Analysis of the 2024 BraTS Meningioma Radiotherapy Planning Automated Segmentation Challenge
Analysis of the 2024 BraTS Meningioma Radiotherapy Planning Automated Segmentation Challenge Open
The 2024 Brain Tumor Segmentation Meningioma Radiotherapy (BraTS-MEN-RT) challenge aimed to advance automated segmentation algorithms using the largest known multi-institutional dataset of 750 radiotherapy planning brain MRIs with expert-a…
View article: Analysis of the BraTS 2023 Intracranial Meningioma Segmentation Challenge
Analysis of the BraTS 2023 Intracranial Meningioma Segmentation Challenge Open
We describe the design and results from the BraTS 2023 Intracranial Meningioma Segmentation Challenge. The BraTS Meningioma Challenge differed from prior BraTS Glioma challenges in that it focused on meningiomas, which are typically benign…
View article: QUBIQ: Uncertainty Quantification for Biomedical Image Segmentation Challenge
QUBIQ: Uncertainty Quantification for Biomedical Image Segmentation Challenge Open
Uncertainty in medical image segmentation tasks, especially inter-rater variability, arising from differences in interpretations and annotations by various experts, presents a significant challenge in achieving consistent and reliable imag…