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View article: Complications and length of stay after enhanced recovery after surgery compared to conventional care in colorectal cancer patients in Northern Italy
Complications and length of stay after enhanced recovery after surgery compared to conventional care in colorectal cancer patients in Northern Italy Open
Background This study aims to evaluate postoperative complications and length of stay in colorectal cancer patients undergoing ERAS vs. non-ERAS procedures in a population-based cohort in northern Italy. Methods Patient characteristics (AS…
View article: A New Era, New Risks: The Cardio-Oncology Perspective on Immunotherapy in Non-Small Cell Lung Cancer
A New Era, New Risks: The Cardio-Oncology Perspective on Immunotherapy in Non-Small Cell Lung Cancer Open
Lung cancer (LC) remains the leading cause of cancer-related mortality worldwide. In recent years, mortality rates have declined due to antismoking policies, earlier detection, and the advent of targeted therapies and immunotherapy, partic…
View article: Longitudinal validation of the PROFFIT questionnaire to assess financial toxicity in cancer patients
Longitudinal validation of the PROFFIT questionnaire to assess financial toxicity in cancer patients Open
PROFFIT validation analyses make the instrument suitable to measure FT in cancer patients within public health systems. In addition, it may represent a valuable tool to plan specific local health policies being sensible to macro-regional v…
View article: Rehabilitation intervention to prevent adverse events related to ADT in patients with metastatic prostate cancer
Rehabilitation intervention to prevent adverse events related to ADT in patients with metastatic prostate cancer Open
This single-arm interventional study aims to evaluate the feasibility and safety of an exercise-based rehabilitation program in hormone-sensitive patients undergoing ADT, alone or combined with other therapies.
View article: A New Era, New Risks: The Cardio-Oncology Perspective on Immunotherapy in Non-Small Cell Lung Cancer
A New Era, New Risks: The Cardio-Oncology Perspective on Immunotherapy in Non-Small Cell Lung Cancer Open
Lung cancer (LC) remains the leading cause of cancer-related mortality worldwide. In recent years, mortality rates have declined due to antismoking policies, earlier detection, and the advent of targeted therapies and immunotherapy, partic…
View article: Genomically matched therapy in advanced solid tumors: the randomized phase 2 ROME trial
Genomically matched therapy in advanced solid tumors: the randomized phase 2 ROME trial Open
Despite recent advancements demonstrating the potential of tumor-agnostic biomarkers to guide effective therapies, randomized evidence supporting the clinical superiority of precision oncology approaches compared to standard therapies rema…
View article: Diagnostic and therapeutic appropriateness in different stages of esophageal/GEJ cancers. The FICOG project
Diagnostic and therapeutic appropriateness in different stages of esophageal/GEJ cancers. The FICOG project Open
Interventions considered appropriate to improve compliance and outcomes of esophageal/GEJ cancer patients were identified.
View article: Germline Findings From Tumor-Only Comprehensive Genomic Profiling in the RATIONAL Study: A Missed Opportunity?
Germline Findings From Tumor-Only Comprehensive Genomic Profiling in the RATIONAL Study: A Missed Opportunity? Open
PURPOSE Tumor comprehensive genomic profiling (CGP) may detect potential germline pathogenic/likely pathogenic (P/LP) alterations as secondary findings. We analyzed the frequency of potentially germline variants and large rearrangements (L…
View article: Patient-reported outcomes (PROs) in clinical trials and in clinical practice: report from the XXI national conference of the Italian Association of Medical Oncology (AIOM)
Patient-reported outcomes (PROs) in clinical trials and in clinical practice: report from the XXI national conference of the Italian Association of Medical Oncology (AIOM) Open
Objective Patient-reported outcomes (PROs) are considered the gold standard for the assessment of subjective symptoms, quality of life (QoL) and patient well-being in both clinical trials and clinical practice. Here, we report key discussi…
View article: Trifluridine/tipiracil regimen in combination with bevacizumab for metastatic colorectal cancer in the third line: an expert opinion
Trifluridine/tipiracil regimen in combination with bevacizumab for metastatic colorectal cancer in the third line: an expert opinion Open
The prolongation of survival along with the preservation of quality of life, possibly avoiding harmful cumulative toxicities, is the primary therapeutic aim for patients with metastatic colorectal cancer (mCRC) in the third-line setting. S…
View article: ‘<i>Brigantaggio</i>’ revisited: historiographical experiences and prospects for research
‘<i>Brigantaggio</i>’ revisited: historiographical experiences and prospects for research Open
This article describes the results of the Progetto di ricerca di interesse nazionale (Research Project of National Interest [PRIN]) ‘ Il brigantaggio rivisitato ’ (‘“ Brigantaggio ” Revisited’), which investigated the practices and imagery…
View article: Atherosclerosis and the Bidirectional Relationship Between Cancer and Cardiovascular Disease: From Bench to Bedside, Part 2 Management
Atherosclerosis and the Bidirectional Relationship Between Cancer and Cardiovascular Disease: From Bench to Bedside, Part 2 Management Open
The first part of this review highlighted the evolving landscape of atherosclerosis, noting emerging cardiometabolic risk factors, the growing impact of exposomes, and social determinants of health. The prominent role of atherosclerosis in…
View article: Atherosclerosis and the Bidirectional Relationship Between Cancer and Cardiovascular Disease: From Bench to Bedside, Part 2 Management
Atherosclerosis and the Bidirectional Relationship Between Cancer and Cardiovascular Disease: From Bench to Bedside, Part 2 Management Open
The first part of this review highlighted the evolving landscape of atherosclerosis, noting emerging cardiometabolic risk factors, the growing impact of exposomes, and social determinants of health. The prominent role of atherosclerosis in…
View article: Impact of Multidisciplinary Team Management on Survival and Recurrence in Stage I–III Colorectal Cancer: A Population-Based Study in Northern Italy
Impact of Multidisciplinary Team Management on Survival and Recurrence in Stage I–III Colorectal Cancer: A Population-Based Study in Northern Italy Open
This study aimed to assess whether multidisciplinary team (MDT) management improves outcomes in patients with stage I–III colorectal cancer (CRC) compared to non-MDT care. This study included 460 CRC patients diagnosed from 2017 to 2018 in…
View article: Precision oncology implementation in a regional-based health care system: A professional consensus to define the pathway
Precision oncology implementation in a regional-based health care system: A professional consensus to define the pathway Open
The direct observation of the current practice in different health care authorities allowed to define ten statements as solution proposals to solve the identified complexities. This methodological approach could be applied in different org…
View article: A Population-Based Analysis of the Cancer Incidence in Individuals under 50 in a Northern Italian Province: Focusing on Regional Disparities and Public Health Implications
A Population-Based Analysis of the Cancer Incidence in Individuals under 50 in a Northern Italian Province: Focusing on Regional Disparities and Public Health Implications Open
International studies have shown an increase in cancer incidence among young adults, raising public concern. This study aims examines trends in the cancer incidence among individuals aged 15–49 years in a province of Northern Italy, coveri…
View article: Survival Risk Score for Invasive Nonmetastatic Breast Cancer: A Real-World Analysis
Survival Risk Score for Invasive Nonmetastatic Breast Cancer: A Real-World Analysis Open
PURPOSE This study aimed to develop a multivariable, weighted overall survival (OS) risk score (SRS) for nonmetastatic (M0) invasive breast cancer (M0-BC, SRS M0-BC ). MATERIALS AND METHODS This study included a training (1,890 patients) a…
View article: Breast-cancer specific comprehensive archive of Patient-Reported Outcome Measures (PROMs) for clinical research and clinical practice in oncology: Results from the PRO4All project
Breast-cancer specific comprehensive archive of Patient-Reported Outcome Measures (PROMs) for clinical research and clinical practice in oncology: Results from the PRO4All project Open
The newly developed archive represents a useful tool to optimize the use of PROMs in the evaluation of treatments in BC patients, promoting a patient-centered approach both in clinical research and practice.
View article: Trends in Asbestos Exposure and Malignant Mesothelioma Incidence in Emilia-Romagna Italy: A Retrospective Study 1996-2023
Trends in Asbestos Exposure and Malignant Mesothelioma Incidence in Emilia-Romagna Italy: A Retrospective Study 1996-2023 Open
Malignant mesothelioma (MM) is a rare but lethal cancer strongly associated with asbestos exposure. This retrospective study examines trends in asbestos exposure in Emilia-Romagna, Northern Italy. Between 1996 and 2023, 3,513 cases of MM w…