André Hennig
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View article: <i>Pneumo</i>Wiki: A pan-genome-based database for the pathogen <i>Streptococcus pneumoniae</i>
<i>Pneumo</i>Wiki: A pan-genome-based database for the pathogen <i>Streptococcus pneumoniae</i> Open
The Gram-positive bacterium Streptococcus pneumoniae is a major human pathogen that exhibits more than 100 different capsular serotypes and considerable genomic variation. S. pneumoniae is also an important model organism for basic and bio…
View article: Differential transcriptome analysis of enterohemorrhagic Escherichia coli strains reveals differences in response to plant-derived compounds
Differential transcriptome analysis of enterohemorrhagic Escherichia coli strains reveals differences in response to plant-derived compounds Open
The current study provides clear evidence that EHEC and EHEC/EAEC strains are able to adjust their gene expression patterns towards metabolization of plant-derived compounds, demonstrating that they may proliferate well in a plant-associat…
View article: Efficient merging of genome profile alignments
Efficient merging of genome profile alignments Open
Motivation Whole-genome alignment (WGA) methods show insufficient scalability toward the generation of large-scale WGAs. Profile alignment-based approaches revolutionized the fields of multiple sequence alignment construction methods by si…
View article: Additional file 3: of Differential transcriptome analysis of enterohemorrhagic Escherichia coli strains reveals differences in response to plant-derived compounds
Additional file 3: of Differential transcriptome analysis of enterohemorrhagic Escherichia coli strains reveals differences in response to plant-derived compounds Open
Table of the shared genome of E. coli O157:H− strain 3072/96, E. coli O104:H4 strain C227–11φcu, E. coli O157:H7 strain Sakai and E. coli strain K-12 substrain MG1655. For every homologous gene group (rows with unique identifier) the genes…
View article: Additional file 2: of Differential transcriptome analysis of enterohemorrhagic Escherichia coli strains reveals differences in response to plant-derived compounds
Additional file 2: of Differential transcriptome analysis of enterohemorrhagic Escherichia coli strains reveals differences in response to plant-derived compounds Open
Differential gene expression according to the respective reference genomes of E. coli O157:H− strain 3072/96, E. coli O104:H4 strain C227–11φcu and E. coli O157:H7 strain Sakai. For each differentially expressed gene, the gene ID, the log2…
View article: Additional file 1: of Differential transcriptome analysis of enterohemorrhagic Escherichia coli strains reveals differences in response to plant-derived compounds
Additional file 1: of Differential transcriptome analysis of enterohemorrhagic Escherichia coli strains reveals differences in response to plant-derived compounds Open
Differential gene expression in the shared genome of E. coli O157:H− strain 3072/96, E. coli O104:H4 strain C227–11φcu and E. coli O157:H7 strain Sakai. For each differentially expressed gene, the gene ID, the log2 fold change between both…
View article: IκBζ is a key transcriptional regulator of IL-36–driven psoriasis-related gene expression in keratinocytes
IκBζ is a key transcriptional regulator of IL-36–driven psoriasis-related gene expression in keratinocytes Open
Proinflammatory cytokine signaling in keratinocytes plays a crucial role in the pathogenesis of psoriasis, a skin disease characterized by hyperproliferation and abnormal differentiation of keratinocytes and infiltration of inflammatory ce…
View article: Efficient Merging of Genome Profile Alignments
Efficient Merging of Genome Profile Alignments Open
Motivation Whole-genome alignment methods show insufficient scalability towards the generation of large-scale whole-genome alignments (WGAs). Profile alignment-based approaches revolutionized the fields of multiple sequence alignment const…
View article: Aureo Wiki The repository of the Staphylococcus aureus research and annotation community
Aureo Wiki The repository of the Staphylococcus aureus research and annotation community Open
In light of continuously accumulating data and knowledge on major human pathogens, comprehensive and up-to-date sources of easily accessible information are urgently required. The AureoWiki database (http://aureowiki.med.uni-greifswald.de)…