Guillaume Mitta
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View article: Diversity and functional specialization of oyster immune cells uncovered by integrative single-cell level investigations
Diversity and functional specialization of oyster immune cells uncovered by integrative single-cell level investigations Open
Mollusks are a major component of animal biodiversity and play a critical role in ecosystems and global food security. The Pacific oyster, Crassostrea (Magallana) gigas , is the most farmed bivalve mollusk in the world and is becoming a mo…
View article: Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations
Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations Open
Mollusks are a major component of animal biodiversity and play a critical role in ecosystems and global food security. The Pacific oyster, Crassostrea (Magallana) gigas, is the most farmed bivalve mollusk in the world and is becoming a mod…
View article: Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations
Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations Open
Mollusks are a major component of animal biodiversity and play a critical role in ecosystems and global food security. The Pacific oyster, Crassostrea (Magallana) gigas, is the most farmed bivalve mollusk in the world and is becoming a mod…
View article: Exploring thermal tolerance across time and space in a tropical bivalve, <i>Pinctada margaritifera</i>
Exploring thermal tolerance across time and space in a tropical bivalve, <i>Pinctada margaritifera</i> Open
Ectotherm vulnerability to climate change is predicted to increase with temperature variation. Still, translating laboratory observations of organisms' heat-stress responses to the natural fluctuating environment remains challenging. In th…
View article: Plastic is in the details: the impact of plastic pollution through a mesocosm experiment
Plastic is in the details: the impact of plastic pollution through a mesocosm experiment Open
Microbial diversity plays key role in marine ecosystems, and quantifying the impact of plastic pollution on these organisms is essential to better anticipate and manage threats to these fragile ecosystems. In nine simplified tropical ecosy…
View article: Diversity and functional specialization of oyster immune cells uncovered by integrative single-cell level investigations
Diversity and functional specialization of oyster immune cells uncovered by integrative single-cell level investigations Open
Mollusks are a major component of animal biodiversity and play a critical role in ecosystems and global food security. The Pacific oyster, Crassostrea (Magallana) gigas , is the most farmed bivalve mollusk in the world and is becoming a mo…
View article: Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations
Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations Open
Mollusks are a major component of animal biodiversity and play a critical role in ecosystems and global food security. The Pacific oyster, Crassostrea (Magallana) gigas, is the most farmed bivalve mollusk in the world and is becoming a mod…
View article: Exploring thermal tolerance across time and space in a tropical bivalve,<i>Pinctada margaritifera</i>
Exploring thermal tolerance across time and space in a tropical bivalve,<i>Pinctada margaritifera</i> Open
Ectotherm’s vulnerability to climate change is predicted to increase with temperature variations. Still, translating laboratory observations of organisms’ heat stress responses to the natural fluctuating environment remains challenging. In…
View article: Cross-talk and mutual shaping between the immune system and the microbiota during an oyster's life
Cross-talk and mutual shaping between the immune system and the microbiota during an oyster's life Open
The Pacific oyster Crassostrea gigas lives in microbe-rich marine coastal systems subjected to rapid environmental changes. It harbours a diversified and fluctuating microbiota that cohabits with immune cells expressing a diversified immun…
View article: Microbial education for marine invertebrate disease prevention in aquaculture
Microbial education for marine invertebrate disease prevention in aquaculture Open
The holobiont theory expands the notion of individual multicellular organisms as a community composed of a host and all its associated microorganisms. This concept has been extensively studied in the field of aquaculture, where increasing …
View article: Temperature and microbe mediated impacts of the San Diego Bay ostreid herpesvirus (OsHV-1) microvariant on juvenile Pacific oysters
Temperature and microbe mediated impacts of the San Diego Bay ostreid herpesvirus (OsHV-1) microvariant on juvenile Pacific oysters Open
The ostreid herpesvirus (OsHV-1) was recently detected in San Diego Bay for the first time in farmed juvenile Pacific oysters (Crassostrea gigas). Due to the virus’ ability to cause mass mortality (50%–100%), it is important to determine t…
View article: Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians
Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians Open
Transmissible cancer cell lines are rare biological entities giving rise to diseases at the crossroads of cancer and parasitic diseases. These malignant cells have acquired the amazing capacity to spread from host to host. They have been d…
View article: Cooperation and cheating orchestrate Vibrio assemblages and polymicrobial synergy in oysters infected with OsHV-1 virus
Cooperation and cheating orchestrate Vibrio assemblages and polymicrobial synergy in oysters infected with OsHV-1 virus Open
Polymicrobial infections threaten the health of humans and animals but remain understudied in natural systems. We recently described the Pacific Oyster Mortality Syndrome (POMS), a polymicrobial disease affecting oyster production worldwid…
View article: Epigenetic variations are more substantial than genetic variations in rapid adaptation of oyster to Pacific oyster mortality syndrome
Epigenetic variations are more substantial than genetic variations in rapid adaptation of oyster to Pacific oyster mortality syndrome Open
Disease emergence is accelerating with global changes. Understanding by which mechanisms host populations can rapidly adapt will be crucial for management practices. Pacific oyster mortality syndrome (POMS) imposes a substantial and recurr…
View article: A core of functional complementary bacteria infects oysters in Pacific Oyster Mortality Syndrome
A core of functional complementary bacteria infects oysters in Pacific Oyster Mortality Syndrome Open
Background The Pacific oyster Crassostrea gigas is one of the main cultivated invertebrate species worldwide. Since 2008, oyster juveniles have been confronted with a lethal syndrome known as the Pacific Oyster Mortality Syndrome (POMS). P…
View article: Epigenetic then genetic variations underpin rapid adaptation of oyster populations (<i>Crassostrea gigas</i>) to Pacific Oyster Mortality Syndrome (POMS)
Epigenetic then genetic variations underpin rapid adaptation of oyster populations (<i>Crassostrea gigas</i>) to Pacific Oyster Mortality Syndrome (POMS) Open
Disease emergence is accelerating in response to human activity-induced global changes. Understanding the mechanisms by which host populations can rapidly adapt to this threat will be crucial for developing future management practices. Pac…
View article: Cooperation and cheating orchestrate<i>Vibrio</i>assemblages and polymicrobial synergy in oysters infected with OsHV-1 virus
Cooperation and cheating orchestrate<i>Vibrio</i>assemblages and polymicrobial synergy in oysters infected with OsHV-1 virus Open
Polymicrobial diseases significantly impact the health of humans and animals but remain understudied in natural systems. We recently described the Pacific Oyster Mortality Syndrome (POMS), a polymicrobial disease that impacts oyster produc…
View article: Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancerous traits and oncogenic pathways shared among bilaterians
Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancerous traits and oncogenic pathways shared among bilaterians Open
Transmissible cancer cell lines are rare biological entities giving rise to diseases at the crossroads of cancer and parasitic diseases. These malignant cells have acquired the amazing capacity to spread from host to host. They have been d…
View article: Table S2.xlsx from Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians
Table S2.xlsx from Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians Open
Table S2: SRA accession numbers of individual raw read sequences deposited in the NCBI database.
View article: Table S6.xlsx from Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians
Table S6.xlsx from Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians Open
Table S6: List of genes clustered by Gene Ontology (GO) terms comprised in enriched biological processes (p.adj<0.05).
View article: Table S3.xlsx from Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians
Table S3.xlsx from Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians Open
Table S3: Samplings of Mytilus mussels used in the study.
View article: Table S7.xlsx from Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians
Table S7.xlsx from Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians Open
Table S7: top 20 genes in connectivity ranking in Protein-protein interaction (PPI) networks of DEGs.
View article: Table S1.txt from Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians
Table S1.txt from Transcriptomics of mussel transmissible cancer MtrBTN2 suggests accumulation of multiple cancer traits and oncogenic pathways shared among bilaterians Open
Table S1: Transcript annotation