Andrea C. Enzinger
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View article: A phase II study of ramucirumab and somatostatin analog therapy in patients with advanced neuroendocrine tumors
A phase II study of ramucirumab and somatostatin analog therapy in patients with advanced neuroendocrine tumors Open
Objectives Well-differentiated neuroendocrine tumors (NET) are highly vascular tumors characterized by their expression of vascular endothelial growth factor (VEGF). This trial investigated the activity of ramucirumab, a monoclonal antibod…
View article: Improving the palliative-procedure decision-making process for patients with peritoneal carcinomatosis: A secondary analysis
Improving the palliative-procedure decision-making process for patients with peritoneal carcinomatosis: A secondary analysis Open
View article: Effects of a change in recall period on reporting severe symptoms: an analysis of a pragmatic multisite trial
Effects of a change in recall period on reporting severe symptoms: an analysis of a pragmatic multisite trial Open
Background Optimal methods for deploying electronic patient-reported outcomes to manage symptoms in routine oncologic practice remain uncertain. The electronic symptom management (eSyM) program asks chemotherapy and surgery patients to sel…
View article: A qualitative analysis of algorithm-based decision support usability testing for symptom management across the trajectory of cancer care: one size does not fit all
A qualitative analysis of algorithm-based decision support usability testing for symptom management across the trajectory of cancer care: one size does not fit all Open
Background Adults with cancer experience symptoms that change across the disease trajectory. Due to the distress and cost associated with uncontrolled symptoms, improving symptom management is an important component of quality cancer care.…
View article: Pain coping, multidisciplinary care, and mHealth: Patients' views on managing advanced cancer pain
Pain coping, multidisciplinary care, and mHealth: Patients' views on managing advanced cancer pain Open
Objective Pain is common among people with advanced cancer. While opioids provide significant relief, incorporating psycho‐behavioral treatments may improve pain outcomes. We examined patients' experiences with pain self‐management and how…
View article: Development and pre-pilot testing of STAMP + CBT: an mHealth app combining pain cognitive behavioral therapy and opioid support for patients with advanced cancer and pain
Development and pre-pilot testing of STAMP + CBT: an mHealth app combining pain cognitive behavioral therapy and opioid support for patients with advanced cancer and pain Open
View article: Experiences of patients with peritoneal carcinomatosis-related complex care needs and their caregivers
Experiences of patients with peritoneal carcinomatosis-related complex care needs and their caregivers Open
View article: A Qualitative Analysis of Algorithm-based Decision Support Usability Testing for Symptom Management Across the Trajectory of Cancer Care: One Size Does Not Fit All
A Qualitative Analysis of Algorithm-based Decision Support Usability Testing for Symptom Management Across the Trajectory of Cancer Care: One Size Does Not Fit All Open
Background Adults with cancer experience symptoms that change across the disease trajectory. Due to the distress and cost associated with uncontrolled symptoms, improving symptom management is an important component of quality cancer care.…
View article: Daily pain and opioid administration in hospitalized patients with cancer: the importance of psychological factors, recent surgery, and current opioid use
Daily pain and opioid administration in hospitalized patients with cancer: the importance of psychological factors, recent surgery, and current opioid use Open
Pain is common and variable in its severity among hospitalized patients with cancer. Although biopsychosocial factors are well established as modulators of chronic pain, less is known about what patient-level factors are associated with wo…
View article: Adaptation of a Multimedia Chemotherapy Educational Intervention for Latinos: Letting Patient Narratives Speak for Themselves
Adaptation of a Multimedia Chemotherapy Educational Intervention for Latinos: Letting Patient Narratives Speak for Themselves Open
View article: Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial
Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial Open
While BRAF inhibitor combinations with EGFR and/or MEK inhibitors have improved clinical efficacy in BRAF V600E colorectal cancer (CRC), response rates remain low and lack durability. Preclinical data suggest that BRAF/MAPK pathway inhibit…
View article: Racial and Ethnic Disparities in Opioid Access and Urine Drug Screening Among Older Patients With Poor-Prognosis Cancer Near the End of Life
Racial and Ethnic Disparities in Opioid Access and Urine Drug Screening Among Older Patients With Poor-Prognosis Cancer Near the End of Life Open
PURPOSE To characterize racial and ethnic disparities and trends in opioid access and urine drug screening (UDS) among patients dying of cancer, and to explore potential mechanisms. METHODS Among 318,549 non-Hispanic White (White), Black, …
View article: Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer
Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer Open
PURPOSE With the growing number of available targeted therapeutics and molecular biomarkers, the optimal care of patients with cancer now depends on a comprehensive understanding of the rapidly evolving landscape of precision oncology, whi…
View article: Racial and ethnic disparities in cancer caregiver burden and potential sociocultural mediators
Racial and ethnic disparities in cancer caregiver burden and potential sociocultural mediators Open
Purpose Black and Hispanic cancer patients experience many worse care quality and health outcomes than non-Hispanic White patients, yet less is known about disparities in caregiving responsibilities and burden among cancer caregivers. Meth…
View article: Racial and ethnic disparities in cancer caregiver burden and potential sociocultural mediators
Racial and ethnic disparities in cancer caregiver burden and potential sociocultural mediators Open
Purpose Black and Hispanic cancer patients experience many worse care quality and health outcomes than non-Hispanic White patients, yet less is known about disparities in caregiving responsibilities and burden among cancer caregivers. Meth…
View article: Cancer Caregivers’ Prognostic and End-of-Life Communication Needs and Experiences and their Impact
Cancer Caregivers’ Prognostic and End-of-Life Communication Needs and Experiences and their Impact Open
View article: Deep Learning for Cancer Symptoms Monitoring on the Basis of Electronic Health Record Unstructured Clinical Notes
Deep Learning for Cancer Symptoms Monitoring on the Basis of Electronic Health Record Unstructured Clinical Notes Open
PURPOSE Symptoms are vital outcomes for cancer clinical trials, observational research, and population-level surveillance. Patient-reported outcomes (PROs) are valuable for monitoring symptoms, yet there are many challenges to collecting P…
View article: Racial/Ethnic Disparities in Cancer Caregiver Burden and Potential Sociocultural Mediators (RP425)
Racial/Ethnic Disparities in Cancer Caregiver Burden and Potential Sociocultural Mediators (RP425) Open
View article: Developing and Field Testing BOLSTER: A Nurse-Led Care Management Intervention to Support Patients and Caregivers following Hospitalization for Gynecologic Cancer-Associated Peritoneal Carcinomatosis
Developing and Field Testing BOLSTER: A Nurse-Led Care Management Intervention to Support Patients and Caregivers following Hospitalization for Gynecologic Cancer-Associated Peritoneal Carcinomatosis Open
Introduction: Peritoneal carcinomatosis (PC) afflicts women with advanced gynecologic cancers. Patients with PC often require ostomies, gastric tubes, or catheters to palliate symptoms, yet patients and caregivers report feel…
View article: Reply to W. E. Rosa et al and T. N. Townsend et al
Reply to W. E. Rosa et al and T. N. Townsend et al Open
In response to our article, 1 Dr Rosa et al 2 provide a sobering reminder of the vast global inequities in opioid access.Less than 0.04% of the global prescription opioid supply is distributed to low-income countries, 3 and more than 70% o…
View article: US Trends in Opioid Access Among Patients With Poor Prognosis Cancer Near the End-of-Life
US Trends in Opioid Access Among Patients With Poor Prognosis Cancer Near the End-of-Life Open
PURPOSE Heightened regulations have decreased opioid prescribing across the United States, yet little is known about trends in opioid access among patients dying of cancer. METHODS Among 270,632 Medicare fee-for-service decedents with poor…
View article: Chronic pain severity, impact, and opioid use among patients with cancer: An analysis of biopsychosocial factors using the CHOIR learning health care system
Chronic pain severity, impact, and opioid use among patients with cancer: An analysis of biopsychosocial factors using the CHOIR learning health care system Open
Background Despite the biopsychosocial underpinnings of chronic noncancer pain, relatively little is known about the contribution of psychosocial factors to chronic cancer pain. The authors aimed to characterize associations between biopsy…
View article: Cancer pain self‐management in the context of a national opioid epidemic: Experiences of patients with advanced cancer using opioids
Cancer pain self‐management in the context of a national opioid epidemic: Experiences of patients with advanced cancer using opioids Open
BACKGROUND The US opioid epidemic has prompted dramatic changes in public attitudes and regulations governing opioid prescribing. Little is known about the experiences of patients with advanced cancer using opioids in the context of the ep…
View article: Leveraging mobile health technology and research methodology to optimize patient education and self-management support for advanced cancer pain
Leveraging mobile health technology and research methodology to optimize patient education and self-management support for advanced cancer pain Open
View article: Leveraging Mobile Health Technology and Multidisciplinary Methodology to Optimize Self-Management Education for Advanced Cancer Pain: Development of STAMP
Leveraging Mobile Health Technology and Multidisciplinary Methodology to Optimize Self-Management Education for Advanced Cancer Pain: Development of STAMP Open
Objective. Pain continues to be a primary and challenging symptom of cancer. We sought to use mobile health (mHealth) technology to tailor psycho-education to better meet patients’ needs. Methods: Using the Agile and mHealth Development an…
View article: Reduced Opioid Prescribing by Oncologists: Progress Made, or Ground Lost?
Reduced Opioid Prescribing by Oncologists: Progress Made, or Ground Lost? Open
View article: The Effect of Disclosing Life Expectancy Information on Patients' Prognostic Understanding: Secondary Outcomes From a Multicenter Randomized Trial of a Palliative Chemotherapy Educational Intervention
The Effect of Disclosing Life Expectancy Information on Patients' Prognostic Understanding: Secondary Outcomes From a Multicenter Randomized Trial of a Palliative Chemotherapy Educational Intervention Open
View article: Effectiveness of a Multimedia Educational Intervention to Improve Understanding of the Risks and Benefits of Palliative Chemotherapy in Patients With Advanced Cancer
Effectiveness of a Multimedia Educational Intervention to Improve Understanding of the Risks and Benefits of Palliative Chemotherapy in Patients With Advanced Cancer Open
ClinicalTrials.gov Identifier: NCT02282722.
View article: SO-26 Clinical efficacy of combined BRAF, MEK, and PD-1 inhibition in BRAFV600E colorectal cancer patients
SO-26 Clinical efficacy of combined BRAF, MEK, and PD-1 inhibition in BRAFV600E colorectal cancer patients Open
View article: Oncologists' perspectives on medical marijuana use by older adults
Oncologists' perspectives on medical marijuana use by older adults Open