Andrea Costantino
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View article: Cancer in children living with HIV: challenges and perspectives in the antiretroviral therapy era
Cancer in children living with HIV: challenges and perspectives in the antiretroviral therapy era Open
View article: The Global Burden of Obstructive Sleep Apnea
The Global Burden of Obstructive Sleep Apnea Open
This study reviewed the global prevalence, health and socioeconomic impact, and management approaches of obstructive sleep apnea. The narrative review examined three key dimensions: (1) worldwide OSA prevalence across different regions, ac…
View article: Trans-oral robotic surgery in the management of malignant oropharyngeal minor salivary gland tumors: A systematic review
Trans-oral robotic surgery in the management of malignant oropharyngeal minor salivary gland tumors: A systematic review Open
This systematic review confirms the safety and feasibility of TORS in the treatment of OPMSG malignancies. However, due to the low quality of included studies, further evidence is needed to establish clinical guidelines.
View article: Temporal and Geographic Trends in HPV Testing for Oropharyngeal Cancer in the United States
Temporal and Geographic Trends in HPV Testing for Oropharyngeal Cancer in the United States Open
Objective Although human papillomavirus (HPV) testing is fundamental to staging, accurate prognosis, patient management, and clinical trial eligibility in oropharyngeal squamous cell carcinoma (OPSCC), national testing patterns remain uncl…
View article: Safety and Postoperative Outcomes of Transoral Surgery for Oropharyngeal Carcinoma in Older Adults
Safety and Postoperative Outcomes of Transoral Surgery for Oropharyngeal Carcinoma in Older Adults Open
Importance Transoral surgery (TOS) has become the primary surgical treatment for oropharyngeal squamous cell carcinoma (OPSCC). However, despite the increasing incidence of OPSCC in older patients, data regarding the safety and postoperati…
View article: Development of machine learning models for fractional flow reserve prediction in angiographically intermediate coronary lesions
Development of machine learning models for fractional flow reserve prediction in angiographically intermediate coronary lesions Open
Background Fractional flow reserve (FFR) represents the gold standard in guiding the decision to proceed or not with coronary revascularization of angiographically intermediate coronary lesion (AICL). Optical coherence tomography (OCT) all…
View article: Surgical outcomes of profunda artery perforator flap in head and neck reconstruction: A systematic review and meta‐analysis
Surgical outcomes of profunda artery perforator flap in head and neck reconstruction: A systematic review and meta‐analysis Open
Objective This study aims to evaluate the efficacy of the profunda artery perforator (PAP) flap in head and neck reconstruction. Methods A single arm meta‐analysis was performed for flap survival rate (primary outcome), reoperation for maj…
View article: Correction to: Preoperative systemic inflammatory markers as prognostic factors in differentiated thyroid cancer: a systematic review and meta-analysis
Correction to: Preoperative systemic inflammatory markers as prognostic factors in differentiated thyroid cancer: a systematic review and meta-analysis Open
View article: Benign acute children myositis: 5 years experience in a tertiary care pediatric hospital
Benign acute children myositis: 5 years experience in a tertiary care pediatric hospital Open
View article: Tumor-infiltrating lymphocytes and tumor-associated macrophages as potential predictors of lymph node metastases in major salivary gland cancers
Tumor-infiltrating lymphocytes and tumor-associated macrophages as potential predictors of lymph node metastases in major salivary gland cancers Open
Purpose The purpose of this study is to define if tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) could represent potential predictors of lymph node metastases (LNM) in salivary gland cancers (SGC). Methods A …
View article: Trans oral robotic surgery for oropharyngeal cancer: A multi institutional experience
Trans oral robotic surgery for oropharyngeal cancer: A multi institutional experience Open
View article: Analysis of Risk Factors for Tracheal Stenosis Managed during COVID-19 Pandemic: A Retrospective, Case-Control Study from Two European Referral Centre
Analysis of Risk Factors for Tracheal Stenosis Managed during COVID-19 Pandemic: A Retrospective, Case-Control Study from Two European Referral Centre Open
Introduction: Benign subglottic/tracheal stenosis (SG/TS) is a life-threatening condition commonly caused by prolonged endotracheal intubation or tracheostomy. Invasive mechanical ventilation was frequently used to manage severe COVID-19, …
View article: Neoadjuvant chemotherapy combined with transoral robotic surgery for stage III and IV laryngeal and hypopharyngeal carcinomas
Neoadjuvant chemotherapy combined with transoral robotic surgery for stage III and IV laryngeal and hypopharyngeal carcinomas Open
View article: Thyrohyoidpexy for urgent laryngeal reconstruction in a case of throat cutting
Thyrohyoidpexy for urgent laryngeal reconstruction in a case of throat cutting Open
Penetrating laryngeal trauma is uncommon but related to potentially life-threatening complications and therefore represent a surgical challenge.[1,2] In fact, prompt and appropriate treatment is mandatory to increase the chances of surviva…
View article: Prognostic Impact of Tumor Immune Microenvironment and Its Predictive Role in Salivary Gland Cancer
Prognostic Impact of Tumor Immune Microenvironment and Its Predictive Role in Salivary Gland Cancer Open
View article: Do We Have Enough Evidence to Specifically Recommend Transoral Robotic Surgery in HPV−Driven Oropharyngeal Cancer? A Systematic Review
Do We Have Enough Evidence to Specifically Recommend Transoral Robotic Surgery in HPV−Driven Oropharyngeal Cancer? A Systematic Review Open
Introduction: International guidelines include transoral robotic surgery (TORS) as an option for selected oropharyngeal squamous cell carcinomas (OPSCCs). In the perspective of treatment de-intensification, many surgeons have started recom…
View article: Development of machine learning models for the prediction of positive surgical margins in transoral robotic surgery (<scp>TORS</scp>)
Development of machine learning models for the prediction of positive surgical margins in transoral robotic surgery (<span>TORS</span>) Open
Purpose To develop machine learning (ML) models for predicting positive margins in patients undergoing transoral robotic surgery (TORS). Methods Data from 453 patients with laryngeal, hypopharyngeal, and oropharyngeal squamous cell carcino…
View article: Cross-Cultural Validation of the Short Version of the Questionnaire of Olfactory Disorders—Negative Statements into Italian: Towards Personalized Patient Care
Cross-Cultural Validation of the Short Version of the Questionnaire of Olfactory Disorders—Negative Statements into Italian: Towards Personalized Patient Care Open
Given the high burden of olfactory dysfunction worldwide, recently increased due to the COVID-19 pandemic, it is mandatory to adopt a specific questionnaire to assess the impact of olfactory impairment on quality of life, to be used in cli…
View article: Contents
Contents Open
View article: Reply to Letter to the Editor regarding “Oncological outcomes of squamous cell carcinoma of the cervical esophagus treated with definitive (chemo‐)radiotherapy: a systematic review and meta‐analysis”
Reply to Letter to the Editor regarding “Oncological outcomes of squamous cell carcinoma of the cervical esophagus treated with definitive (chemo‐)radiotherapy: a systematic review and meta‐analysis” Open
View article: Reply to Adrian, G. Comment on “Russo et al. Does Tumor Volume Have a Prognostic Role in Oropharyngeal Squamous Cell Carcinoma? A Systematic Review and Meta-Analysis. Cancers 2022, 14, 2465”
Reply to Adrian, G. Comment on “Russo et al. Does Tumor Volume Have a Prognostic Role in Oropharyngeal Squamous Cell Carcinoma? A Systematic Review and Meta-Analysis. Cancers 2022, 14, 2465” Open
The authors raised some interesting points [...]
View article: Role of surgical margins in transoral robotic surgery: A question yet to be answered
Role of surgical margins in transoral robotic surgery: A question yet to be answered Open
View article: Does Tumor Volume Have a Prognostic Role in Oropharyngeal Squamous Cell Carcinoma? A Systematic Review and Meta-Analysis
Does Tumor Volume Have a Prognostic Role in Oropharyngeal Squamous Cell Carcinoma? A Systematic Review and Meta-Analysis Open
The aim of this study was to assess the prognostic value of tumor volume in oropharyngeal squamous cell carcinoma (OPSCC). The study was performed according to the PRISMA guidelines. A total of 1417 patients with a median age of 59.3 years…
View article: Oncological outcomes of squamous cell carcinoma of the cervical esophagus treated with definitive (chemo-)radiotherapy: a systematic review and meta-analysis
Oncological outcomes of squamous cell carcinoma of the cervical esophagus treated with definitive (chemo-)radiotherapy: a systematic review and meta-analysis Open
View article: Elective neck irradiation in the management of esthesioneuroblastoma: a systematic review and meta-analysis
Elective neck irradiation in the management of esthesioneuroblastoma: a systematic review and meta-analysis Open
Background: There is no consensus about the optimal management of the neck in clinically node negative esthesioneuroblastoma (ENB). The aim of this study is to assess the impact of elective neck irradiation (ENI) in terms of regional disea…
View article: Dataset related to article "Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019"
Dataset related to article "Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019" Open
This record contains raw data related to article “Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019" Importance: Early diagnosis of coronavirus disease 2019 (COVID-19) may help control the diffusion of…
View article: Dataset related to article "Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019"
Dataset related to article "Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019" Open
This record contains raw data related to article “Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019" Importance: Early diagnosis of coronavirus disease 2019 (COVID-19) may help control the diffusion of…
View article: Anatomical‐based classification for transoral base of tongue resection
Anatomical‐based classification for transoral base of tongue resection Open
Background To propose a classification of transoral base of tongue (BOT) procedures able to provide uniform terminology in order to better define postoperative results. Methods The classification resulted from the consensus of the differen…
View article: TELEMEDICINE IN IBD: GOOD TRUST FROM OUTPATIENTS DURING THE COVID-19 PANDEMIC IN MILAN (LOMBARDY)
TELEMEDICINE IN IBD: GOOD TRUST FROM OUTPATIENTS DURING THE COVID-19 PANDEMIC IN MILAN (LOMBARDY) Open
Background and Aim During the recent COVID-19 pandemic, telemedicine has enabled many IBD patients worldwide to get access to remote assistance. Some positive reports on the use of telemedicine among patients and healthcare providers have …
View article: Diagnostic accuracy of a pocket-size ultrasound device in identifying liver surface nodularity for fibrosis staging in chronic liver disease
Diagnostic accuracy of a pocket-size ultrasound device in identifying liver surface nodularity for fibrosis staging in chronic liver disease Open