Andrea Faggiano
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View article: Targeting Myocardial Mechanics in Children and Adolescents with Obesity and Non-Elevated Blood Pressure: A Meta-Regression Study
Targeting Myocardial Mechanics in Children and Adolescents with Obesity and Non-Elevated Blood Pressure: A Meta-Regression Study Open
Background/Objectives: Although global longitudinal strain (GLS) appears more sensitive than the ejection fraction in uncovering subtle left ventricular (LV) dysfunction, evidence of impaired LV mechanics in children/adolescents with obesi…
View article: New onset left atrial dilatation in the general population: A quarter-century follow-up
New onset left atrial dilatation in the general population: A quarter-century follow-up Open
The incidence of LAE from mid to late adulthood occurs in a large clinically relevant fraction of participants and is affected by initial LAD, BMI and 25-year change in BMI, LVMI and 24-h PP. The findings provided by the present study supp…
View article: Therapeutic inertia in achieving lipid targets in secondary cardiovascular prevention: a multicentre study from the itacare-p network
Therapeutic inertia in achieving lipid targets in secondary cardiovascular prevention: a multicentre study from the itacare-p network Open
Introduction The 2019 ESC/EAS guidelines recommend stringent low-density lipoprotein cholesterol (LDL-C) targets of ≤55 mg/dL for very high-risk patients and ≤40 mg/dL for those with multiple events within two years. Despite the availabili…
View article: Elevated Blood Pressure and Cardiac Mechanics in Children and Adolescents: A Systematic Review and Meta-Analysis
Elevated Blood Pressure and Cardiac Mechanics in Children and Adolescents: A Systematic Review and Meta-Analysis Open
INTRODUCTION Evidence on left ventricular (LV) mechanics, assessed by speckle tracking echocardiography (STE), in children and adolescents with elevated blood pressure (BP)/hypertension is scanty. AIM The aim of the present meta-analysis w…
View article: Drug coated balloon angioplasty for de novo coronary lesions in large vessels: a systematic review and meta-analysis
Drug coated balloon angioplasty for de novo coronary lesions in large vessels: a systematic review and meta-analysis Open
View article: Therapeutic Inertia in Dyslipidemia Management for Secondary Cardiovascular Prevention: Results from the Italian ITACARE-P Network
Therapeutic Inertia in Dyslipidemia Management for Secondary Cardiovascular Prevention: Results from the Italian ITACARE-P Network Open
Background/Objectives: This study assessed the proportion of secondary cardiovascular prevention patients who achieved low-density lipoprotein (LDL) cholesterol targets as per the 2019 ESC/EAS Dyslipidemia Guidelines. We also evaluated whe…
View article: Prognostic value of myocardial computed tomography–derived extracellular volume in severe aortic stenosis requiring aortic valve replacement: a systematic review and meta-analysis
Prognostic value of myocardial computed tomography–derived extracellular volume in severe aortic stenosis requiring aortic valve replacement: a systematic review and meta-analysis Open
Computed tomography (CT)-derived extracellular volume (ECV) fraction is a non-invasive method to quantify myocardial fibrosis. Evaluating CT-ECV during aortic valve replacement (AVR) planning CT in severe aortic stenosis (AS) may aid progn…
View article: Efficacy and Safety of Sirolimus‐Coated Balloon Angioplasty in De Novo Lesions in Large Coronary Vessels: A Propensity Score‐Matched Study
Efficacy and Safety of Sirolimus‐Coated Balloon Angioplasty in De Novo Lesions in Large Coronary Vessels: A Propensity Score‐Matched Study Open
Background Evidence regarding drug‐coated balloon (DCB)‐only angioplasty in de novo lesions of large vessels is still limited and mainly focused on paclitaxel‐coated balloon. We aimed to analyze the safety and efficacy of sirolimus‐coated …
View article: Anthracycline-Induced Subclinical Right Ventricular Dysfunction in Breast Cancer Patients: A Systematic Review and Meta-Analysis
Anthracycline-Induced Subclinical Right Ventricular Dysfunction in Breast Cancer Patients: A Systematic Review and Meta-Analysis Open
Aim: This meta-analysis aims to evaluate the impact of anthracycline chemotherapy on subclinical right ventricular (RV) dysfunction in breast cancer patients, using traditional echocardiographic parameters and strain-based measures, such a…
View article: Doxorubicin-related cardiotoxicity: review of fundamental pathways of cardiovascular system injury
Doxorubicin-related cardiotoxicity: review of fundamental pathways of cardiovascular system injury Open
View article: Extensive myocardial calcifications: a systematic literature review of a rare pathological phenomenon
Extensive myocardial calcifications: a systematic literature review of a rare pathological phenomenon Open
Introduction Myocardial calcifications (MC) represent a relatively rare pathological process, which may accompany different cardiovascular conditions and can be broadly categorized as dystrophic or metastatic. Myocardial infarction (MI) ha…
View article: Unraveling the Enigma of Moderate Aortic Stenosis: Challenges and Future Prospects
Unraveling the Enigma of Moderate Aortic Stenosis: Challenges and Future Prospects Open
According to current guidelines, only clinical surveillance is recommended for patients with moderate aortic valve stenosis (AS), while aortic valve replacement may be considered in patients undergoing surgery for other indications. Recent…
View article: Imaging approaches in risk stratification of patients with coronary artery disease: a narrative review
Imaging approaches in risk stratification of patients with coronary artery disease: a narrative review Open
Coronary artery disease (CAD) is the most common cause of mortality among adults worldwide. In the prognostic risk stratification of these patients, crucial determinants are lumen stenosis, total volume and composition of the plaque. Consi…
View article: Reply to the letter regarding the article ‘Subclinical systolic dysfunction in genotype‐positive phenotype‐negative relatives of dilated cardiomyopathy patients: A systematic review and meta‐analysis’
Reply to the letter regarding the article ‘Subclinical systolic dysfunction in genotype‐positive phenotype‐negative relatives of dilated cardiomyopathy patients: A systematic review and meta‐analysis’ Open
We would like to express our gratitude to Dr. Albulushi and colleagues for their interest in our work and for raising insightful questions that allow us to clarify certain concepts.
View article: Extracellular vesicles characterization in patients with hypertrophic cardiomyopathy
Extracellular vesicles characterization in patients with hypertrophic cardiomyopathy Open
Background: Hypertrophic cardiomyopathy (HCM) is diagnosed according to the presence of morphological and functional traits of the heart, often in the presence of genetic mutations. A specific biomarker assessing the aetiopathology of this…
View article: Levosimendan in cardiac amyloidosis: Unveiling promising paths
Levosimendan in cardiac amyloidosis: Unveiling promising paths Open
View article: Subclinical systolic dysfunction in genotype‐positive phenotype‐negative relatives of dilated cardiomyopathy patients: A systematic review and meta‐analysis
Subclinical systolic dysfunction in genotype‐positive phenotype‐negative relatives of dilated cardiomyopathy patients: A systematic review and meta‐analysis Open
The absence of left ventricular (LV) dilatation and systolic dysfunction, as assessed by LV ejection fraction (LVEF), in family members of genetically confirmed dilated cardiomyopathy (DCM) patients, carrying pathogenic (P) or likely patho…
View article: UNRAVELING GENDER DISPARITIES AND PROGNOSTIC INSIGHTS IN MODERATE AORTIC STENOSIS: A RETROSPECTIVE STUDY
UNRAVELING GENDER DISPARITIES AND PROGNOSTIC INSIGHTS IN MODERATE AORTIC STENOSIS: A RETROSPECTIVE STUDY Open
Aortic stenosis (AS) is the most prevalent valvular heart disease in developed countries, associated with reduced survival if severe AS remains untreated. Recent reports note unfavorable outcomes in moderate AS (mAS) patients, challenging …
View article: Do We Need New Electrocardiographic Criteria for Left Ventricular Hypertrophy? The Case of the Peguero–Lo Presti Criterion. A Narrative Review
Do We Need New Electrocardiographic Criteria for Left Ventricular Hypertrophy? The Case of the Peguero–Lo Presti Criterion. A Narrative Review Open
The cardiovascular risk associated with left ventricular hypertrophy (LVH) in the community and, particularly, in the hypertensive fraction of the general population, represents the rationale for its timely and accurate identification in o…
View article: Extracellular vesicles in cardiomyopathies: A narrative review
Extracellular vesicles in cardiomyopathies: A narrative review Open
View article: Melatonin mitigates oxidative damage induced by anthracycline: a systematic-review and meta-analysis of murine models
Melatonin mitigates oxidative damage induced by anthracycline: a systematic-review and meta-analysis of murine models Open
Background Oxidative stress induced by the excessive production of reactive oxygen species is one of the primary mechanisms implicated in anthracycline (ANT)-induced cardiotoxicity. There is a strong clinical need for a molecule capable of…
View article: Aortic Valve Stenosis and Cancer: Problems of Management
Aortic Valve Stenosis and Cancer: Problems of Management Open
Aortic valve stenosis and malignancy frequently coexist and share the same risk factors as atherosclerotic disease. Data reporting the prognosis of patients with severe aortic stenosis and cancer are limited. Tailoring the correct and opti…
View article: Issue Information
Issue Information Open
Understanding the pathogenesis of
View article: Case report: Sodium-glucose cotransporter 2 inhibitors induce left ventricular reverse remodeling in anthracycline-related cardiac dysfunction—a case series
Case report: Sodium-glucose cotransporter 2 inhibitors induce left ventricular reverse remodeling in anthracycline-related cardiac dysfunction—a case series Open
Purpose To describe the efficacy and safety of sodium-glucose cotransporter 2 inhibitors as a specific treatment for anthracycline-related cardiac dysfunction in a small real-world population. Methods Seven patients with anthracycline-rela…
View article: Aortic dilatation and cardiovascular events: a new piece of the puzzle?
Aortic dilatation and cardiovascular events: a new piece of the puzzle? Open
View article: Aortic valve stenosis and cancer: problems of management
Aortic valve stenosis and cancer: problems of management Open
Aortic valve stenosis and malignancy frequently coexist and share the same risk factors as atherosclerotic disease. Data reporting the prognosis of patients with severe aortic stenosis and cancer are limited. Tailoring the correct and most…
View article: Induced myocardial ischemia in candidates to liver transplantation without evidence of heart disease
Induced myocardial ischemia in candidates to liver transplantation without evidence of heart disease Open
A very low prevalence of CAD in a selected population of ESLD at intermediate to high CV risk was found. A screening based on stress echocardiography and CCTA resulted in low incidence of post-LT acute coronary events in ELSD patients. CAD…
View article: Acute heart failure: How can we predict subsequent improvement in systolic function?
Acute heart failure: How can we predict subsequent improvement in systolic function? Open
The authors report no conflicts of interest. Data sharing is not applicable to this article as no new data were created or analyzed in this study.
View article: Issue Information
Issue Information Open
Combined use of double Doppler Tei index
View article: P87 GENETIC CARDIOMYOPATHIES: THE FIRST YEAR OF THE FONDAZIONE IRCCS CÀ GRANDA OSPEDALE MAGGIORE POLICLINICO OF MILAN DEDICATED CLINICAL SERVICE
P87 GENETIC CARDIOMYOPATHIES: THE FIRST YEAR OF THE FONDAZIONE IRCCS CÀ GRANDA OSPEDALE MAGGIORE POLICLINICO OF MILAN DEDICATED CLINICAL SERVICE Open
Objectives Cardiac genetic counselling and testing for inherited cardiomyopathies have become essential aspects of cardiovascular care. A genetic diagnosis in a family can offer an invaluable tool for cascade genetic testing of at–risk rel…