Andrea Grillo
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View article: Atherosclerotic renal artery stenosis in the post-CORAL Trial Era. A narrative review
Atherosclerotic renal artery stenosis in the post-CORAL Trial Era. A narrative review Open
Atherosclerotic renal artery stenosis (ARAS) represents a common manifestation of systemic atherosclerosis and remains an underrecognized cause of secondary hypertension, chronic kidney disease, and cardiovascular morbidity. Although often…
View article: Sex Differences in 24 H Blood Pressure in Night-Shift Workers
Sex Differences in 24 H Blood Pressure in Night-Shift Workers Open
Background/Objectives: Gender Medicine addresses how sex- and gender-based differences influence people’s health. Blood pressure (BP), which is the leading global risk factor for cardiovascular disease, shows a sexual dimorphism. This is s…
View article: PNPLA3 Polymorphism Is Inversely Correlated with Aortic Stiffness in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease Without Fibrosis
PNPLA3 Polymorphism Is Inversely Correlated with Aortic Stiffness in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease Without Fibrosis Open
Metabolic dysfunction-associated steatotic liver disease (MASLD) corresponds to the condition of increased hepatic fat levels, which is the leading cause of hepatic failure and carcinoma. It is also an independent risk factor for cardiovas…
View article: Beat-to-beat variability of aortic pulse wave velocity: implications for aortic stiffness measurements
Beat-to-beat variability of aortic pulse wave velocity: implications for aortic stiffness measurements Open
Objectives: Aortic pulse wave velocity (aPWV) predicts cardiovascular risk. Being the reference method for aortic stiffness evaluation, invasive aPWV is also recommended for validation of noninvasive devices. Because of intrinsic haemodyna…
View article: Associations between central and brachial blood pressure in patients with hypertension and aortovascular disease: Implications for clinical practice
Associations between central and brachial blood pressure in patients with hypertension and aortovascular disease: Implications for clinical practice Open
Central blood pressure (CBP) measurements, compared to brachial blood pressure (bBP), offer a superior predictive accuracy for aortovascular disease outcomes. This emphasises the distinctiveness of central hemodynamic metrics such as CBP, …
View article: Developing technologies to assess vascular ageing: a roadmap from VascAgeNet
Developing technologies to assess vascular ageing: a roadmap from VascAgeNet Open
Vascular ageing (vascular ageing) is the deterioration of arterial structure and function which occurs naturally with age, and which can be accelerated with disease. Measurements of vascular ageing are emerging as markers of cardiovascular…
View article: Simulation-guided auscultatory training before graduation is associated with better auscultatory skills in residents
Simulation-guided auscultatory training before graduation is associated with better auscultatory skills in residents Open
Introduction A growing body of scientific evidence shows that simulation-guided auscultatory training can significantly improve the skills of medical students. Nevertheless, it remains to be elucidated if this training has any long-term im…
View article: Preliminary Study on Pulse Wave Changes in Patients with Inflammatory Arthropathies Treated with bDMARDs
Preliminary Study on Pulse Wave Changes in Patients with Inflammatory Arthropathies Treated with bDMARDs Open
Background: Patients with inflammatory arthropathies exhibit an increased cardiovascular disease (CVD) risk as compared to the general population, which is not fully quantified by the conventional CVD risk scores. Biotechnological disease-…
View article: Atrial Fibrillation and Early Vascular Aging: Clinical Implications, Methodology Issues and Open Questions—A Review from the VascAgeNet COST Action
Atrial Fibrillation and Early Vascular Aging: Clinical Implications, Methodology Issues and Open Questions—A Review from the VascAgeNet COST Action Open
Atrial fibrillation (AF), the most common cardiac arrhythmia, is associated with adverse CV outcomes. Vascular aging (VA), which is defined as the progressive deterioration of arterial function and structure over a lifetime, is an independ…
View article: Myocardial oxygen supply and demand imbalance predicts mortality in older nursing home residents: The <scp>PARTAGE</scp> study
Myocardial oxygen supply and demand imbalance predicts mortality in older nursing home residents: The <span>PARTAGE</span> study Open
Background A mismatch between myocardial oxygen supply and demand is the most common cause of ischemic myocardial injury in older persons. The subendocardial viability ratio (SEVR) can usefully estimate the degree of myocardial perfusion r…
View article: Preliminary Study on the Effect of a Night Shift on Blood Pressure and Clock Gene Expression
Preliminary Study on the Effect of a Night Shift on Blood Pressure and Clock Gene Expression Open
Night shift work has been found to be associated with a higher risk of cardiovascular and cerebrovascular disease. One of the underlying mechanisms seems to be that shift work promotes hypertension, but results have been variable. This cro…
View article: Microcirculatory and Rheological Adaptive Mechanisms at High Altitude in European Lowlander Hikers and Nepalese Highlanders
Microcirculatory and Rheological Adaptive Mechanisms at High Altitude in European Lowlander Hikers and Nepalese Highlanders Open
Background: Physical activity at high-altitudes is increasingly widespread, both for tourist trekking and for the growing tendency to carry out sports and training activities at high-altitudes. Acute exposure to this hypobaric–hypoxic cond…
View article: Vascular ageing: moving from bench towards bedside
Vascular ageing: moving from bench towards bedside Open
Prevention of cardiovascular disease (CVD) remains one of the largest public health challenges of our time. Identifying individuals at increased cardiovascular risk at an asymptomatic, sub-clinical stage is of paramount importance for mini…
View article: Blood pressure variability: methodological aspects, clinical relevance and practical indications for management - a European Society of Hypertension position paper ∗
Blood pressure variability: methodological aspects, clinical relevance and practical indications for management - a European Society of Hypertension position paper ∗ Open
Blood pressure is not a static parameter, but rather undergoes continuous fluctuations over time, as a result of the interaction between environmental and behavioural factors on one side and intrinsic cardiovascular regulatory mechanisms o…
View article: Haemodynamic Adaptive Mechanisms at High Altitude: Comparison between European Lowlanders and Nepalese Highlanders
Haemodynamic Adaptive Mechanisms at High Altitude: Comparison between European Lowlanders and Nepalese Highlanders Open
Background: Exposure to high altitudes determines several adaptive mechanisms affecting in a complex way the whole cardiovascular, respiratory, endocrine systems because of the hypobaric hypoxic condition. The aim of our study was to evalu…
View article: Estimation of Aortic Stiffness with Bramwell–Hill Equation: A Comparative Analysis with Carotid–Femoral Pulse Wave Velocity
Estimation of Aortic Stiffness with Bramwell–Hill Equation: A Comparative Analysis with Carotid–Femoral Pulse Wave Velocity Open
Aortic stiffness is an important clinical parameter for predicting cardiovascular events. Carotid–femoral pulse wave velocity (cf-PWV) has been proposed for performing this evaluation non-invasively; however, it requires dedicated equipmen…
View article: Arterial Stiffness in Thyroid and Parathyroid Disease: A Review of Clinical Studies
Arterial Stiffness in Thyroid and Parathyroid Disease: A Review of Clinical Studies Open
Growing evidence shows that arterial stiffness measurement provides important prognostic information and improves clinical stratification of cardiovascular risk. Thyroid and parathyroid diseases are endocrine diseases with a relevant cardi…
View article: Non-Invasive Assessment of Arterial Stiffness: Pulse Wave Velocity, Pulse Wave Analysis and Carotid Cross-Sectional Distensibility: Comparison between Methods
Non-Invasive Assessment of Arterial Stiffness: Pulse Wave Velocity, Pulse Wave Analysis and Carotid Cross-Sectional Distensibility: Comparison between Methods Open
Background: The stiffening of large elastic arteries is currently estimated in research and clinical practice by propagative and non-propagative models, as well as parameters derived from aortic pulse waveform analysis. Methods: Common car…
View article: Meta-analysis on the Association Between Thyroid Hormone Disorders and Arterial Stiffness
Meta-analysis on the Association Between Thyroid Hormone Disorders and Arterial Stiffness Open
Context Aortic stiffness is an emerging predictor of cardiovascular morbidity and mortality. Current data about the effect of subclinical and overt thyroid hormone disorders on aortic stiffness are often conflicting. Objective Primary outc…
View article: Assessment of Phasic Changes of Vascular Size by Automated Edge Tracking-State of the Art and Clinical Perspectives
Assessment of Phasic Changes of Vascular Size by Automated Edge Tracking-State of the Art and Clinical Perspectives Open
Assessment of vascular size and of its phasic changes by ultrasound is important for the management of many clinical conditions. For example, a dilated and stiff inferior vena cava reflects increased intravascular volume and identifies pat…
View article: Comparison Between Invasive and Noninvasive Methods to Estimate Subendocardial Oxygen Supply and Demand Imbalance
Comparison Between Invasive and Noninvasive Methods to Estimate Subendocardial Oxygen Supply and Demand Imbalance Open
Background Estimation of the balance between subendocardial oxygen supply and demand could be a useful parameter to assess the risk of myocardial ischemia. Evaluation of the subendocardial viability ratio (SEVR, also known as Buckberg inde…
View article: Meta-analysis on the Effect of Mild Primary Hyperparathyroidism and Parathyroidectomy Upon Arterial Stiffness
Meta-analysis on the Effect of Mild Primary Hyperparathyroidism and Parathyroidectomy Upon Arterial Stiffness Open
Context Current data about the cardiovascular manifestations of mild primary hyperparathyroidism (pHPT) are often conflicting. Pulse wave velocity (PWV) is the gold standard for assessing aortic stiffness, and it predicts cardiovascular mo…
View article: “ <scp>COVID‐Mask</scp> ”: An atypical livedoid manifestation of <scp>COVID</scp> ‐19 observed in a Northern Italy hospital
“ <span>COVID‐Mask</span> ”: An atypical livedoid manifestation of <span>COVID</span> ‐19 observed in a Northern Italy hospital Open
Dermatologic TherapyVolume 33, Issue 4 e13701 Letter "COVID-Mask": An atypical livedoid manifestation of COVID-19 observed in a Northern Italy hospital Claudio Conforti, Claudio Conforti orcid.org/0000-0001-5126-8873 Department of Dermatol…
View article: Sodium Intake and Hypertension
Sodium Intake and Hypertension Open
The close relationship between hypertension and dietary sodium intake is widely recognized and supported by several studies. A reduction in dietary sodium not only decreases the blood pressure and the incidence of hypertension, but is also…
View article: Noninvasive Estimation of Aortic Stiffness Through Different Approaches
Noninvasive Estimation of Aortic Stiffness Through Different Approaches Open
Aortic pulse wave velocity is a worldwide accepted index to evaluate aortic stiffness and can be assessed noninvasively by several methods. This study sought to determine if commonly used noninvasive devices can all accurately estimate aor…
View article: Unreliable Estimation of Aortic Pulse Wave Velocity Provided by the Mobil‐O‐Graph Algorithm‐Based System in Marfan Syndrome
Unreliable Estimation of Aortic Pulse Wave Velocity Provided by the Mobil‐O‐Graph Algorithm‐Based System in Marfan Syndrome Open
Background Several devices have been proposed to assess arterial stiffness in clinical daily use over the past few years, by estimating aortic pulse wave velocity (PWV) from a single measurement of brachial oscillometric blood pressure, us…
View article: Non-invasive evaluation of myocardial supply-demand balance from the analysis of pulse waveform: from validation to clinical application
Non-invasive evaluation of myocardial supply-demand balance from the analysis of pulse waveform: from validation to clinical application Open
La valutazione del bilancio tra l'apporto e la domanda di ossigeno nel miocardio è utile per predire e diagnosticare l'ischemia miocardica e l'infarto miocardico di tipo 2, condizioni che rappresentano una parte crescente del carico sanita…
View article: Systolic time intervals assessed from analysis of the carotid pressure waveform
Systolic time intervals assessed from analysis of the carotid pressure waveform Open
The timing of electro-mechanical cardiac events can be reliably obtained from the carotid pulse waveform and carotid-femoral PWV, evaluated using arterial tonometry. Systolic time intervals assessed with this approach showed good agreement…
View article: Morning blood pressure surge: pathophysiology, clinical relevance and therapeutic aspects
Morning blood pressure surge: pathophysiology, clinical relevance and therapeutic aspects Open
Morning hours are the period of the day characterized by the highest incidence of major cardiovascular events including myocardial infarction, sudden death or stroke. They are also characterized by important neurohormonal changes, in parti…