Andrea L.O. Hebb
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View article: Plasma extracellular vesicle sampling from high grade gliomas demonstrates a small RNA signature indicative of disease and identifies lncRNA RPPH1 as a high grade glioma biomarker.
Plasma extracellular vesicle sampling from high grade gliomas demonstrates a small RNA signature indicative of disease and identifies lncRNA RPPH1 as a high grade glioma biomarker. Open
Background: High grade gliomas (HGGs) and cells of the tumour microenvironment (TME) secrete extracellular vesicles(EVs) into the plasma that contain genetic and protein cargo, which function in paracrine signaling. Isolation of these EVs …
View article: P.128 Pituitary apoplexy: a retrospective single center cohort study
P.128 Pituitary apoplexy: a retrospective single center cohort study Open
Background: Pituitary apoplexy is a rare clinical syndrome resulting from infarction or hemorrhage of a pituitary tumor. Here, we present a large single center retrospective cohort study of patients with apoplexy. Methods: Patients with sy…
View article: BIOM-19. PLASMA EXTRACELLULAR VESICLE SAMPLING FROM HIGH GRADE GLIOMA PATIENTS DEMONSTRATES A SMALL RNA SIGNATURE INDICATIVE OF DISEASE AND IDENTIFIES LNCRNA RPPH1 AS A HIGH GRADE GLIOMA BIOMARKER
BIOM-19. PLASMA EXTRACELLULAR VESICLE SAMPLING FROM HIGH GRADE GLIOMA PATIENTS DEMONSTRATES A SMALL RNA SIGNATURE INDICATIVE OF DISEASE AND IDENTIFIES LNCRNA RPPH1 AS A HIGH GRADE GLIOMA BIOMARKER Open
High grade gliomas (HGGs) and cells of the tumour microenvironment (TME) secrete extracellular vesicles (EVs) into the plasma that contain genetic and protein cargo which function in paracrine signaling. Isolation of these EVs and their ca…
View article: OR2804 Endocrine And Vision Outcomes Following 90Yttrium Therapy For Cystic Sellar Lesions—A Prospective Cohort Study
OR2804 Endocrine And Vision Outcomes Following 90Yttrium Therapy For Cystic Sellar Lesions—A Prospective Cohort Study Open
Disclosure: M.A. MacLean: None. S. Ahmad: None. A.L. Hebb: None. A. Tahir: None. R. Greene: None. D.B. Clarke: None. S.A. Imran: None. Background: Untreated cystic sellar lesions can cause vision loss, endocrine dysfunction, and obstructiv…
View article: Stroke Treatment: Focus on Neuroprotection and EPO
Stroke Treatment: Focus on Neuroprotection and EPO Open
Erythropoietin (EPO) is a neuroprotective chemical that is produced by the brain in response to stroke-induced hypoxia. Stroke was first described by Hippocrates (460-377 BC) as apoplexy, the Greek term for “struck down by violence”. In mo…
View article: In-Hospital Endocrinology Consultation After Transsphenoidal Surgery: Is It Always Necessary?
In-Hospital Endocrinology Consultation After Transsphenoidal Surgery: Is It Always Necessary? Open
Background: Patients with sellar masses undergoing transsphenoidal surgery (TSS) frequently develop endocrine dysfunction; therefore, in-hospital endocrinology consultation (IHEC) is recommended. However, we wondered whether routine endocr…
View article: Mechanism of paediatric medulloblastoma
Mechanism of paediatric medulloblastoma Open
Paediatric Medulloblastoma, while rare, is a cancer that affects hundreds of children each year between the ages 0-14 years.Prognosis is typically poor and dependent on variant signalling pathways underlying pathogenesis of tumours.The fol…
View article: MON-LB076 Patterns of Secondary Hormonal Deficiency Vary among Different Types of Sellar Masses Despite Similar Tumour Size at Presentation
MON-LB076 Patterns of Secondary Hormonal Deficiency Vary among Different Types of Sellar Masses Despite Similar Tumour Size at Presentation Open
BACKGROUND: Secondary hormonal deficiency (SHD) is common in patients with sellar masses (SM); however, it is unclear if the rate and type of SHD at presentation is related to the size or type of SM. We conducted a study comparing SHD in v…
View article: Introspective Analysis of Knowledge Translation and Dissemination Within a Primary Health Care Model
Introspective Analysis of Knowledge Translation and Dissemination Within a Primary Health Care Model Open
The Canadian Health Care system is mandated to follow a Primary Health Care (PHC) model where nurses are at the forefront both in direct care, accessibility, technology and public education.The following discussion focuses on client educat…
View article: Nursing Leadership Strategies for Implementing Nursing Full Scope of Practice into Acute Care Team-Led Healthcare Settings
Nursing Leadership Strategies for Implementing Nursing Full Scope of Practice into Acute Care Team-Led Healthcare Settings Open
The nursing new model of care was introduced in Nova Scotia as an innovative cost-efficient measure to integrate registered...
View article: Shared decision making and decisional conflict in the Management of Vestibular Schwannoma: A prospective cohort study
Shared decision making and decisional conflict in the Management of Vestibular Schwannoma: A prospective cohort study Open
Background Patients with vestibular schwannomas (VS) are faced with complex management decisions. Watchful waiting, surgical resection, and radiation are all viable options with associated risks and benefits. We sought to determine if pati…
View article: CJN volume 44 issue 5 Cover and Front matter
CJN volume 44 issue 5 Cover and Front matter Open
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View article: Radiological Growth Patterns of Prolactinomas and Nonfunctioning Adenomas
Radiological Growth Patterns of Prolactinomas and Nonfunctioning Adenomas Open
Objectives: To compare growth patterns of nonfunctioning and prolactin-producing pituitary macroadenomas, and to find whether their specific growth patterns are associated with clinically significant effects on vision. Materials and Method…
View article: CJN volume 44 issue 2 Cover and Front matter
CJN volume 44 issue 2 Cover and Front matter Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
View article: Visualization of <sup>90</sup>Yttrium Colloid Within a Cystic Craniopharyngioma Using PET/CT/MRI Fusion
Visualization of <sup>90</sup>Yttrium Colloid Within a Cystic Craniopharyngioma Using PET/CT/MRI Fusion Open
An abstract is not available for this content. As you have access to this content, full HTML content is provided on this page. A PDF of this content is also available in through the ‘Save PDF’ action button.
View article: Normalized Apparent Diffusion Coefficient in the Prognostication of Patients with Glioblastoma Multiforme
Normalized Apparent Diffusion Coefficient in the Prognostication of Patients with Glioblastoma Multiforme Open
Background: Glioblastoma multiforme (GBM) is known to have poor prognosis, with no available imaging marker that can predict survival at the time of diagnosis. Diffusion weighted images are used in characterisation of cellularity and necro…
View article: CJN volume 43 issue 1 Cover and Front matter
CJN volume 43 issue 1 Cover and Front matter Open
An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.