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View article: Association of inflammatory markers with depression and anxiety in female patients with primary Sjögren’s syndrome
Association of inflammatory markers with depression and anxiety in female patients with primary Sjögren’s syndrome Open
Introduction: Primary Sjögren’s syndrome (pSS) is a chronic autoimmune disease affecting exocrine glands and is frequently accompanied by depression and anxiety. Proinflammatory cytokines, particularly interleukin 6 (IL-6), have been impli…
View article: National recommendations of the Working group for laboratory diagnostics of autoimmune diseases of the Croatian Society of Medical Biochemistry and Laboratory Medicine: Assessment of antineutrophil cytoplasmic antibodies (ANCA)
National recommendations of the Working group for laboratory diagnostics of autoimmune diseases of the Croatian Society of Medical Biochemistry and Laboratory Medicine: Assessment of antineutrophil cytoplasmic antibodies (ANCA) Open
The family of antineutrophil cytoplasmic antibodies (ANCA) includes autoantibodies targeting proteins within the primary granules of neutrophils and lysosomes of monocytes. So far, proteinase 3 (PR3) and myeloperoxidase (MPO) are considere…
View article: Hashimoto’s Thyroiditis and Dry Eye Disease
Hashimoto’s Thyroiditis and Dry Eye Disease Open
Hashimoto’s thyroiditis (HT) is an autoimmune thyroid disease with characteristic lymphocytic infiltration and fibrosis. Chronic autoimmune changes that occur in the thyroid gland in HT may also affect the lacrimal gland. Objectives: This …
View article: Assesment of Salivary and Serum Levels of HBD2 in Patients with Chronic Angioedema
Assesment of Salivary and Serum Levels of HBD2 in Patients with Chronic Angioedema Open
Background/Objectives: Human β-defensin 2 (HBD2) is a protein that plays an important role in activating the immune system by modulating spinal pathways and the inflammatory response. According to previous research, HBD2 was proven to be i…
View article: Assessment of Salivary and Serum Levels of hBD2 in Patients with Chronic Angioedema
Assessment of Salivary and Serum Levels of hBD2 in Patients with Chronic Angioedema Open
Background: Human β-defensin 2 (HBD2) is a protein important in immune system activation, produced by epithelial cells, mainly as a result of contact with microorganisms or the action of various pro-inflammatory cytokines. According t…
View article: Repository of intra- and inter-run variations of quantitative autoantibody assays: a European multicenter study
Repository of intra- and inter-run variations of quantitative autoantibody assays: a European multicenter study Open
Objectives No reference data are available on repositories to measure precision of autoantibody assays. The scope of this study was to document inter- and intra-run variations of quantitative autoantibody assays based on a real-world large…
View article: Corrigendum to: Assessment of antinuclear antibodies (ANA): National recommendations on behalf of the Croatian society of medical biochemistry and laboratory medicine
Corrigendum to: Assessment of antinuclear antibodies (ANA): National recommendations on behalf of the Croatian society of medical biochemistry and laboratory medicine Open
This is a correction of Biochem Med (Zagreb) 2021;31(2):020502, DOI: https://doi.org/10.11613/BM.2021.020502. Since the publication of the article, the authors have noticed some errors.
View article: Assessment of antinuclear antibodies (ANA): National recommendations on behalf of the Croatian society of medical biochemistry and laboratory medicine
Assessment of antinuclear antibodies (ANA): National recommendations on behalf of the Croatian society of medical biochemistry and laboratory medicine Open
Antinuclear antibodies (ANA) represent a family of autoantibodies targeting ubiquitous cellular constituents and are a hallmark of systemic inflammatory autoimmune rheumatic diseases named connective tissue diseases (CTD). The gold standar…
View article: Comparison of diagnostic accuracy for eight SARS-CoV-2 serological assays
Comparison of diagnostic accuracy for eight SARS-CoV-2 serological assays Open
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serological tests have been suggested as an additional diagnostic tool in highly suspected cases with a negative molecular test and determination of seroprevalence …
View article: Quality and best practice in medical laboratories: specific requests for autoimmunity testing
Quality and best practice in medical laboratories: specific requests for autoimmunity testing Open
Special conditions associated with laboratory autoimmune testing are not well compatible with recent developments in regulatory frameworks such as EN/ISO 15189 accreditation or in vitro diagnostic medical device regulation (IVD-R). In addi…
View article: α-1 Antitrypsin Genotype-Phenotype Discrepancy in a 42-Year-Old Man Who Carries the Null-Allele
α-1 Antitrypsin Genotype-Phenotype Discrepancy in a 42-Year-Old Man Who Carries the Null-Allele Open
Background Alpha-1-antitrypsin (A1AT) deficiency is a hereditary condition caused by mutations in the SERPINA1 gene and associated with lung emphysema and liver disease. Laboratory testing in suspected A1AT deficiency involves quantifying …
View article: Differences in Disease Demographics and Associated CoMorbidities in Working Men and Women with Type 2 Diabetes Mellitus
Differences in Disease Demographics and Associated CoMorbidities in Working Men and Women with Type 2 Diabetes Mellitus Open
The study was undertaken to investigate the differences in the disease demographics and associated co-morbidities in working men and working women with Type 2 Diabetes Mellitus (T2DM).The study was carried out in 292 working men and workin…
View article: Prikaz slučaja: mjerenje antikoagulacijskog učinka dabigatrana kod pacijentice s akutnim bubrežnim zatajenjem Case report: anticoagulant effect of dabigatran in patient with acte renal failure
Prikaz slučaja: mjerenje antikoagulacijskog učinka dabigatrana kod pacijentice s akutnim bubrežnim zatajenjem Case report: anticoagulant effect of dabigatran in patient with acte renal failure Open
View article: Henoch-Schönlein purpura in the third trimester of pregnancy
Henoch-Schönlein purpura in the third trimester of pregnancy Open
Henoch-Schönlein purpura (HSP) is an IgA-mediated small vessels' vasculitis that affects the skin, intestines and kidneys. Pregnancy has been reported as an exacerbating factor. We present the case of a 24-year-old primigravida with…
View article: Comparison of Enzymatic Assay for HBA1C Measurement (Abbott Architect) With Capillary Electrophoresis (Sebia Minicap Flex Piercing Analyser)
Comparison of Enzymatic Assay for HBA1C Measurement (Abbott Architect) With Capillary Electrophoresis (Sebia Minicap Flex Piercing Analyser) Open
The enzymatic method proved to be comparable to the CE method in analytical performances; however, certain interferences can influence the measurements of each method.
View article: Current practice in laboratory diagnostics of autoimmune diseases in Croatia. Survey of the Working group for laboratory diagnostics of autoimmune diseases of the Croatian Society of Medical Biochemistry and Laboratory Medicine
Current practice in laboratory diagnostics of autoimmune diseases in Croatia. Survey of the Working group for laboratory diagnostics of autoimmune diseases of the Croatian Society of Medical Biochemistry and Laboratory Medicine Open
Results indicate the need of creating recommendations and algorithms in order to harmonize the approach to laboratory diagnostics of autoimmune diseases in Croatia.
View article: Monoklonska gamapatija otkrivena pri pretraživanju na oligoklonski IgG tijekom dijagnostičke obrade multiple skleroze
Monoklonska gamapatija otkrivena pri pretraživanju na oligoklonski IgG tijekom dijagnostičke obrade multiple skleroze Open