Explanipedia

Early Use of Thrombopietin Receptor Agonists (Tpo-Ras) in Clinical Practice: Results from an Italian Survey on Behalf of the Gimema Working Group Anemia and Thrombocytopenia. Open

Mariasanta Napolitano, Elisa Lucchini, Maria Rosaria De Paolis, Andreacarola Urso, Alessandro Lucchesi , et al. · 2025

Staphylococcus aureus adapts to exploit collagen-derived proline during chronic infection Open

Andreacarola Urso, Ian R. Monk, Ying-Tsun Chen, Camilla Predella, Tania Wong Fok Lung , et al. · 2024

Staphylococcus aureus is a pulmonary pathogen associated with substantial human morbidity and mortality. As vaccines targeting virulence determinants have failed to be protective in humans, other factors are likely involved in pathogenesis…

A Unique Cellular Organization of Human Distal Airways and Its Disarray in Chronic Obstructive Pulmonary Disease Open

Samir Rustam, Yuanyuan Hu, Seyed Babak Mahjour, André F. Rendeiro, Hiranmayi Ravichandran , et al. · 2024

Rationale: Remodeling and loss of distal conducting airways, including preterminal and terminal bronchioles (pre-TBs/TBs), underlie progressive airflow limitation in chronic obstructive pulmonary disease (COPD). The cellular basis of these…

85 Ketogenesis promotes tolerance to Pseudomonas aeruginosa infection in the cystic fibrosis lung Open

K. Tomlinson, Ying-Tsun Chen, Anders Junker, Andreacarola Urso, Tiffany Tuck Chin Wong , et al. · 2023

Ketogenesis promotes tolerance to Pseudomonas aeruginosa pulmonary infection Open

Kira L. Tomlinson, Ying-Tsun Chen, Alex Junker, Andreacarola Urso, Tania Wong Fok Lung , et al. · 2023

A Unique Cellular Organization of Human Distal Airways and Its Disarray in Chronic Obstructive Pulmonary Disease Open

Samir Rustam, Yang Hu, Seyed Babak Mahjour, André F. Rendeiro, Hiranmayi Ravichandran , et al. · 2023

Rationale: Remodeling and loss of distal conducting airways, including preterminal and terminal bronchioles (pre-TBs/TBs), underlie progressive airflow limitation in chronic obstructive pulmonary disease (COPD). The cellular basis o…

Anti-Inflammatory Metabolites in the Pathogenesis of Bacterial Infection Open

Andreacarola Urso, Alice Prince · 2022

Host and pathogen metabolism have a major impact on the outcome of infection. The microenvironment consisting of immune and stromal cells drives bacterial proliferation and adaptation, while also shaping the activity of the immune system. …

Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection Open

Tania Wong Fok Lung, Daniel Charytonowicz, Kristin G. Beaumont, Shivang S. Shah, Shwetha Hara Sridhar , et al. · 2022

Large Airway Bronchial Wash Lipidomics as Novel Biomarkers for Chronic Lung Allograft Dysfunction Open

Miguel M. Leiva‐Juárez, Domenica Federica Briganti, Andreacarola Urso, S. Russum, Luke Benvenuto , et al. · 2022

A Unique Cellular Organization of Human Distal Airways and Its Disarray in Chronic Obstructive Pulmonary Disease Open

Samir Rustam, Yang Hu, Seyed Babak Mahjour, Scott H. Randell, André F. Rendeiro , et al. · 2022

In the human lung, terminal bronchioles (TBs), the most distal conducting airways, open to respiratory bronchioles (RBs) that lead to the alveolar region where gas exchange takes place. This transition occurs in pulmonary lobules, lung tis…

Contributions of bile acids to gastrointestinal physiology as receptor agonists and modifiers of ion channels Open

Stephen J. Keely, Andreacarola Urso, Alexandr V. Ilyaskin, Christoph Korbmacher, Nigel W. Bunnett , et al. · 2021

Bile acids (BAs) are known to be important regulators of intestinal motility and epithelial fluid and electrolyte transport. Over the past two decades, significant advances in identifying and characterizing the receptors, transporters, and…

Aspiration of conjugated bile acids predicts adverse lung transplant outcomes and correlates with airway lipid and cytokine dysregulation Open

Andreacarola Urso, Miguel M. Leiva‐Juárez, Domenica Federica Briganti, Beatrice Aramini, Luke Benvenuto , et al. · 2021

Fundoplication after lung transplantation in patients with systemic sclerosis–related end-stage lung disease Open

Miguel M. Leiva‐Juárez, Andreacarola Urso, Joseph Costa, B.P. Stanifer, Joshua Sonett , et al. · 2021

Introduction: Gastroesophageal reflux and aspiration are risk factors for chronic lung allograft dysfunction in lung transplant recipients. Patients with systemic sclerosis are at an increased risk of aspiration due to esophageal dysmotili…

Histologic Phenotypes and Outcomes in Single vs Double Lung Transplantation among Recipients with Interstitial Lung Disease Open

Miguel M. Leiva‐Juárez, Luke Benvenuto, Joseph Costa, Andreacarola Urso, B.P. Stanifer , et al. · 2021

Carbapenemase-Producing Klebsiella Pneumoniae ST258 Activates the T6SS in Response to the Host Metabolite Itaconate to Promote Bacterial Adaptation to the Lung Open

T. Wong, Wanzhuo Shi, Andreacarola Urso, Medini K. Annavajhala, Anne‐Catrin Uhlemann , et al. · 2020

Donor surfactant protein A2 polymorphism and lung transplant survival Open

F. D’Ovidio, Joanna Floros, Beatrice Aramini, David J. Lederer, Susan DiAngelo , et al. · 2019

Purpose Gene polymorphisms of surfactant proteins, key players in lung innate immunity, have been associated with various lung diseases. The aim of this study was to investigate the potential association between variations within the surfa…

Bile acids inhibit cholinergic constriction in proximal and peripheral airways from humans and rodents Open

Andreacarola Urso, F. D’Ovidio, Dingbang Xu, Charles W. Emala, Nigel W. Bunnett , et al. · 2019

Duodenogastroesophageal reflux (DGER) is associated with chronic lung disease. Bile acids (BAs) are established markers of DGER aspiration and are important risk factors for reduced post-transplant lung allograft survival by disrupting the…

Andreacarola Urso YOU? Author Swipe