Andreas Buchbender
YOU?
Author Swipe
View article: FUBP1 is a general splicing factor facilitating 3′ splice site recognition and splicing of long introns
FUBP1 is a general splicing factor facilitating 3′ splice site recognition and splicing of long introns Open
Splicing of pre-mRNAs critically contributes to gene regulation and proteome expansion in eukaryotes, but our understanding of the recognition and pairing of splice sites during spliceosome assembly lacks detail. Here, we identify the mult…
View article: An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2
An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2 Open
The recognition of cis -regulatory RNA motifs in human transcripts by RNA binding proteins (RBPs) is essential for gene regulation. The molecular features that determine RBP specificity are often poorly understood. Here, we combined NMR st…
View article: Improved library preparation with the new iCLIP2 protocol
Improved library preparation with the new iCLIP2 protocol Open
Individual-nucleotide resolution UV crosslinking and immunoprecipitation (iCLIP) is a state-of-the-art technology to map the RNA interaction sites of an RNA-binding protein (RBP) across the transcriptome. Here, we present the new iCLIP2 pr…