Andreas Schiwy
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View article: On the utilisation and characterisation of external biotransformation systems in <i>in vitro</i> toxicology: a critical review of the scientific literature with guidance recommendations
On the utilisation and characterisation of external biotransformation systems in <i>in vitro</i> toxicology: a critical review of the scientific literature with guidance recommendations Open
Incorporating biotransformation capabilities into in vitro assays represents one of the most critical challenges in toxicology, facilitating the transition from in vivo models to integrated in vitro strategies. Although emerging technologi…
View article: S9 metabolism integrated CALUX® assay reveals invisible endocrine activities of sediments from two eutrophic freshwater lakes in China
S9 metabolism integrated CALUX® assay reveals invisible endocrine activities of sediments from two eutrophic freshwater lakes in China Open
Endocrine-disrupting compounds (EDCs) are of increasing concern due to their prevalence in aquatic ecosystems and potential harm to aquatic life and human health. The in vitro chemically activated luciferase gene expression (CALUX®) assay …
View article: One like all? Behavioral response range of native and invasive amphipods to neonicotinoid exposure
One like all? Behavioral response range of native and invasive amphipods to neonicotinoid exposure Open
Native and invasive species often occupy similar ecological niches and environments where they face comparable risks from chemical exposure. Sometimes, invasive species are phylogenetically related to native species, e.g. they may come fro…
View article: Biotechnological metabolization system has the potential to improve the predictive ability of the fish embryo acute toxicity (FET) test with the zebrafish (Danio rerio)
Biotechnological metabolization system has the potential to improve the predictive ability of the fish embryo acute toxicity (FET) test with the zebrafish (Danio rerio) Open
Background The fish embryo acute toxicity (FET) test with the zebrafish ( Danio rerio ) was developed to assess the acute fish toxicity of chemicals or environmental samples as a replacement for the Acute Fish Test (AFT) with juvenile fish…
View article: Soose et al. 2023 STOTEN Data.csv
Soose et al. 2023 STOTEN Data.csv Open
We present behavioral raw-data related to Soose et al. 2023.
View article: Following the adverse outcome pathway from micronucleus to cancer using H2B-eGFP transgenic healthy stem cells
Following the adverse outcome pathway from micronucleus to cancer using H2B-eGFP transgenic healthy stem cells Open
In vitro assessment of genotoxicity as an early warning tool for carcinogenicity mainly relies on recording cytogenetic damages (micronuclei, nucleoplasmic bridges) in tumour-derived mammalian cell lines like V79 or CHO. The forecasting po…