Andreas Seas
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View article: Transfacet transforaminal lumbar interbody fusion (TF-TLIF) results in greater change in spondylolisthesis and posterior disc height compared to percutaneous TLIF (Perc-TLIF) or minimally invasive TLIF (MIS-TLIF): a retrospective study
Transfacet transforaminal lumbar interbody fusion (TF-TLIF) results in greater change in spondylolisthesis and posterior disc height compared to percutaneous TLIF (Perc-TLIF) or minimally invasive TLIF (MIS-TLIF): a retrospective study Open
Although there are limitations, the TF-TLIF shows promising results compared to MIS-TLIF and Perc-TLIF approaches, with improved spondylolisthesis reduction and posterior disc height correction.
View article: Magnetic resonance–guided focused ultrasound thalamotomy as a viable option for essential tremor after deep brain stimulation explantation: illustrative case
Magnetic resonance–guided focused ultrasound thalamotomy as a viable option for essential tremor after deep brain stimulation explantation: illustrative case Open
BACKGROUND Essential tremor (ET) has limited pharmacological treatments, and deep brain stimulation (DBS) has emerged as an effective surgical intervention. DBS, although effective and safe, is inherently invasive. Patients at high risk fo…
View article: Study Protocol: Single-Blinded, Controlled, Clinical Trial Evaluating the Feasibility of Spinal Cord Stimulation for Improving Neuropathic Pain and Rehabilitation Outcomes in Patients With Thoracic Spinal Cord Injury
Study Protocol: Single-Blinded, Controlled, Clinical Trial Evaluating the Feasibility of Spinal Cord Stimulation for Improving Neuropathic Pain and Rehabilitation Outcomes in Patients With Thoracic Spinal Cord Injury Open
BACKGROUND AND OBJECTIVES: Traumatic thoracic spinal cord injury (SCI) is complicated by chronic neuropathic pain and neurological deficits including bowel and bladder dysfunction. Treatment with spinal cord stimulation (SCS) has demonstra…
View article: Perceived Barriers to a Neurosurgical Career for Medical Students and Unspecialized Residents Worldwide: A Systematic Literature Review
Perceived Barriers to a Neurosurgical Career for Medical Students and Unspecialized Residents Worldwide: A Systematic Literature Review Open
Globally, a large deficit of neurosurgeons exists along with a growing burden of disease requiring neurosurgical care. Also, considerable geographical disparities remain in the neurosurgical workforce distribution. Augmenting and diversify…
View article: Building sustainable neurosurgical capacity: lessons from the Duke Division of Global Neurosurgery and Neurology
Building sustainable neurosurgical capacity: lessons from the Duke Division of Global Neurosurgery and Neurology Open
Neurosurgery has long faced significant disparities in access to care in low- and middle-income countries (LMICs), where millions lack access to timely, lifesaving neurosurgical interventions. The Duke Division of Global Neurosurgery and N…
View article: DISP-01. FACTORS AFFECTING POST-ABLATION OUTCOMES AND TRIAL ENROLLMENT IN DIVERSE PATIENTS UNDERGOING LASER INTERSTITIAL THERMAL THERAPY
DISP-01. FACTORS AFFECTING POST-ABLATION OUTCOMES AND TRIAL ENROLLMENT IN DIVERSE PATIENTS UNDERGOING LASER INTERSTITIAL THERMAL THERAPY Open
BACKGROUND Laser interstitial thermal therapy (LITT) is a surgical treatment for progressive brain metastases (BM) following stereotactic radiosurgery (SRS). Although LITT has been increasingly accepted, little is known regarding factors i…
View article: Four-tract tractography: multiparametric direct targeting of the dentatorubrothalamic tract
Four-tract tractography: multiparametric direct targeting of the dentatorubrothalamic tract Open
This video article presents a case study of a 70-year-old male with medically refractory essential tremor treated with magnetic resonance–guided focused ultrasound (MRgFUS). Following an initial successful ablation of the right thalamus, t…
View article: SRGD-03 PRESENTATION AND POST-OPERATIVE OUTCOMES IN DIVERSE PATIENTS RECEIVING LASER ABLATION FOR CENTRAL NERVOUS SYSTEM METASTASES
SRGD-03 PRESENTATION AND POST-OPERATIVE OUTCOMES IN DIVERSE PATIENTS RECEIVING LASER ABLATION FOR CENTRAL NERVOUS SYSTEM METASTASES Open
OBJECTIVE Laser interstitial thermal therapy (LITT) is a minimally invasive option for the management of intracranial pathologies, including radiographically progressive tumors following stereotactic radiosurgery. Although LITT has been in…
View article: Magnetic resonance imaging–guided focused ultrasound thalamotomy for essential tremor in a patient with von Willebrand disease: perioperative optimization for patients with coagulopathies. Illustrative case
Magnetic resonance imaging–guided focused ultrasound thalamotomy for essential tremor in a patient with von Willebrand disease: perioperative optimization for patients with coagulopathies. Illustrative case Open
BACKGROUND Essential tremor (ET) is one of the most common movement disorders worldwide. In medically refractory ET, deep brain stimulation (DBS) of the ventral intermediate nucleus of the thalamus is the current standard of care. However,…
View article: Commentary on “Use of ChatGPT for Determining Clinical and Surgical Treatment of Lumbar Disc Herniation With Radiculopathy: A North American Spine Society Guideline Comparison”
Commentary on “Use of ChatGPT for Determining Clinical and Surgical Treatment of Lumbar Disc Herniation With Radiculopathy: A North American Spine Society Guideline Comparison” Open
See the article "Use of ChatGPT for Determining Clinical and Surgical Treatment of Lumbar Disc Herniation With Radiculopathy: A North American Spine Society Guideline Comparison" in Volume 21 on page 149.
View article: Subcallosal cingulate deep brain stimulation evokes two distinct cortical responses via differential white matter activation
Subcallosal cingulate deep brain stimulation evokes two distinct cortical responses via differential white matter activation Open
Subcallosal cingulate (SCC) deep brain stimulation (DBS) is an emerging therapy for refractory depression. Good clinical outcomes are associated with the activation of white matter adjacent to the SCC. This activation produces a signature …
View article: Disparities in the treatment of movement disorders using deep brain stimulation
Disparities in the treatment of movement disorders using deep brain stimulation Open
OBJECTIVE Deep brain stimulation (DBS) is a well-established treatment for Parkinson’s disease (PD) and essential tremor (ET). Although the prevalence of PD and ET can vary by sex and race, little is known about the accessibility of neuros…
View article: Scoping review on the state of racial disparities literature in the treatment of neurosurgical disease: a call for action
Scoping review on the state of racial disparities literature in the treatment of neurosurgical disease: a call for action Open
OBJECTIVE Racial disparities are ubiquitous across medicine in the US. This study aims to assess the evidence of racial disparities within neurosurgery and across its subspecialties, with a specific goal of quantifying the distribution of …
View article: DDDR-29. TARGETING FGFR FUSIONS: A CASE OF CATEQUENTINIB (AL3818) AND TEMOZOLOMIDE COMBINATION THERAPY FOR RECURRENT MGMT METHYLATED TACC-FGFR FUSION POSITIVE GLIOBLASTOMA
DDDR-29. TARGETING FGFR FUSIONS: A CASE OF CATEQUENTINIB (AL3818) AND TEMOZOLOMIDE COMBINATION THERAPY FOR RECURRENT MGMT METHYLATED TACC-FGFR FUSION POSITIVE GLIOBLASTOMA Open
BACKGROUND There is no gold-standard for the management of recurrent glioblastoma (GBM). However, advances at the interface of molecular testing and rational drug design have opened avenues for personalized medicine. Here we describe the c…
View article: Abstract Number ‐ 282: Surgical Treatment for Moyamoya Disease with Coexisting Autoimmune Conditions: A Systematic Review
Abstract Number ‐ 282: Surgical Treatment for Moyamoya Disease with Coexisting Autoimmune Conditions: A Systematic Review Open
Introduction There have been several studies of Moyamoya disease (MMD) with concurrent autoimmune (AI) disease. It has been proposed that there may be a causal or synergistic effect of autoimmune and inflammatory conditions in patients wit…
View article: Abstract Number ‐ 281: Clinical and Epidemiological Characteristics of Moyamoya Disease Presenting with Concomitant Autoimmune Conditions
Abstract Number ‐ 281: Clinical and Epidemiological Characteristics of Moyamoya Disease Presenting with Concomitant Autoimmune Conditions Open
Introduction Moyamoya disease was first described in the 1950’s. After over six decades, however, the underlying etiology of Moyamoya still remains unknown. It has been postulated that underlying inflammatory or autoimmune (AI) processes m…
View article: The Scope, Growth, and Inequities of the Global Neurosurgery Literature: A Bibliometric Analysis
The Scope, Growth, and Inequities of the Global Neurosurgery Literature: A Bibliometric Analysis Open
Despite recent growth, the number of global neurosurgery publications arising from LMICs pales in comparison to those from HICs. Collaborative efforts between certain HICs and LMICs have likely contributed to the observed increase in LMIC …
View article: Machine Learning to Predict Successful Opioid Dose Reduction or Stabilization After Spinal Cord Stimulation
Machine Learning to Predict Successful Opioid Dose Reduction or Stabilization After Spinal Cord Stimulation Open
BACKGROUND: Spinal cord stimulation (SCS) effectively reduces opioid usage in some patients, but preoperatively, there is no objective measure to predict who will most benefit. OBJECTIVE: To predict successful reduction or stabilization of…
View article: Machine Learning for Predicting Discharge Disposition After Traumatic Brain Injury
Machine Learning for Predicting Discharge Disposition After Traumatic Brain Injury Open
BACKGROUND: Current traumatic brain injury (TBI) prognostic calculators are commonly used to predict the mortality and Glasgow Outcome Scale, but these outcomes are most relevant for severe TBI. Because mild and moderate TBI rarely reaches…
View article: Building Opportunities and Overtures in Science and Technology: Establishing an Early Intervention, Multi-Level, Continuous STEM Pathway Program.
Building Opportunities and Overtures in Science and Technology: Establishing an Early Intervention, Multi-Level, Continuous STEM Pathway Program. Open
Building Opportunities and Overtures in Science and Technology (BOOST) is an early intervention, multi-level, continuous STEM pathway program. Born out of a partnership between Duke University and Durham Public Schools, the BOOST program p…
View article: SURG-15. UPFRONT MRI-GUIDED STEREOTACTIC LASER-ABLATION IN NEWLY DIAGNOSED GLIOBLASTOMA: A MULTICENTER REVIEW OF SURVIVAL OUTCOMES COMPARED TO A MATCHED COHORT OF BIOPSY-ONLY PATIENTS
SURG-15. UPFRONT MRI-GUIDED STEREOTACTIC LASER-ABLATION IN NEWLY DIAGNOSED GLIOBLASTOMA: A MULTICENTER REVIEW OF SURVIVAL OUTCOMES COMPARED TO A MATCHED COHORT OF BIOPSY-ONLY PATIENTS Open
Laser ablation (LA) is used as an upfront treatment in patients with deep seated newly diagnosed Glioblastoma (nGBM). We evaluated the outcomes of LA in patients with nGBM and compared them with a matched biopsy-only cohort. 24 nGBM patien…
View article: Upfront Magnetic Resonance Imaging-Guided Stereotactic Laser-Ablation in Newly Diagnosed Glioblastoma: A Multicenter Review of Survival Outcomes Compared to a Matched Cohort of Biopsy-Only Patients
Upfront Magnetic Resonance Imaging-Guided Stereotactic Laser-Ablation in Newly Diagnosed Glioblastoma: A Multicenter Review of Survival Outcomes Compared to a Matched Cohort of Biopsy-Only Patients Open
BACKGROUND Laser ablation (LA) is used as an upfront treatment in patients with deep seated newly diagnosed Glioblastoma (nGBM). OBJECTIVE To evaluate the outcomes of LA in patients with nGBM and compare them with a matched biopsy-only coh…
View article: A temporal examination of calcium signaling in cancer- from tumorigenesis, to immune evasion, and metastasis
A temporal examination of calcium signaling in cancer- from tumorigenesis, to immune evasion, and metastasis Open
This review discusses the current understanding of Ca2+ in cancer. By addressing Ca2+ facilitated angiogenesis, immune evasion, metastasis, and drug resistance, we anticipate future avenues for development of Ca2+ as a nexus of therapy.