Oleg Mediannikov
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View article: Advancements and challenges in bioinformatics tools for microbial genomics in the last decade: Toward the smart integration of bioinformatics tools, digital resources, and emerging technologies for the analysis of complex biological data
Advancements and challenges in bioinformatics tools for microbial genomics in the last decade: Toward the smart integration of bioinformatics tools, digital resources, and emerging technologies for the analysis of complex biological data Open
Over the past decade, microbial genomics has been transformed by advances in sequencing technologies and bioinformatics, enabling the transition from targeted gene markers to complete genome assemblies and ecological scale metagenomic surv…
View article: Re-emergence of Diphtheria in Guinea: An Outbreak Analysis of Vaccination and Disease Control Perspectives
Re-emergence of Diphtheria in Guinea: An Outbreak Analysis of Vaccination and Disease Control Perspectives Open
Background This study presented the key characteristics of patients who tested positive for diphtheria during the outbreak in the Republic of Guinea in 2023 and assessed the influence of some risk factors on disease development. Methods Th…
View article: Analysis of two screens reveals a correlation between antiamoebic and anti-tubulin activities of phenothiazine and triphenylethylene derivatives
Analysis of two screens reveals a correlation between antiamoebic and anti-tubulin activities of phenothiazine and triphenylethylene derivatives Open
For phenothiazine and triphenylethylene derivatives—including triflupromazine and tamoxifen—modulation of heat-induced tubulin polymerization strongly correlates with antiamoebic activity.
View article: Molecular detection of Potential Novel Mansonella species (Filarioidea: Onchocercidae) in equine and Culicoides enderleini from Africa
Molecular detection of Potential Novel Mansonella species (Filarioidea: Onchocercidae) in equine and Culicoides enderleini from Africa Open
A new genotype of a filarial worm from the Mansonella genus was determined in three donkeys from Algeria, as well as from four horses and two Culicoides enderleini biting midges from Senegal. Phylogenetic analysis based on the ITS1 and rRN…
View article: Circulation of<i>Klebsiella pneumoniae</i>strains between the termites, chimpanzees and humans
Circulation of<i>Klebsiella pneumoniae</i>strains between the termites, chimpanzees and humans Open
The emergence and multiplication of multi-resistant microbes is becoming a major concern in medicine and scientific research, requiring an integrated, global approach to prevent their spread and develop new therapeutic solutions . Klebsiel…
View article: Prevalence of Respiratory Pathogens in Nasopharyngeal Swabs of Febrile Patients with or without Respiratory Symptoms in the Niakhar Area of Rural Senegal
Prevalence of Respiratory Pathogens in Nasopharyngeal Swabs of Febrile Patients with or without Respiratory Symptoms in the Niakhar Area of Rural Senegal Open
Acute respiratory tract infections are one of the leading causes of morbidity and mortality worldwide. More data are needed on circulating respiratory microorganisms in different geographical areas and ecosystems. We analyzed nasopharyngea…
View article: Aetiology of non-malaria acute febrile illness fever in children in rural Guinea-Bissau: a prospective cross-sectional investigation
Aetiology of non-malaria acute febrile illness fever in children in rural Guinea-Bissau: a prospective cross-sectional investigation Open
Background With growing use of parasitological tests to detect malaria and decreasing incidence of the disease in Africa; it becomes necessary to increase the understanding of causes of non-malaria acute febrile illness (NMAFI) towards pro…
View article: Identification of termites from Gabon using MALDI-TOF MS
Identification of termites from Gabon using MALDI-TOF MS Open
Termites are one of the most common pests that damage wood and other cellulosic materials. Although Africa has more varieties of termite species than any other continent, few entomological studies have been conducted in Gabon. Identifying …
View article: Development of a Technique Using Artificial Membrane for In Vitro Rearing of Body Lice Pediculus humanus humanus
Development of a Technique Using Artificial Membrane for In Vitro Rearing of Body Lice Pediculus humanus humanus Open
Human lice are the only hematophagous ectoparasites specific to human hosts. They transmit epidemic typhus, trench fever and relapsing fever, diseases which have already caused millions of deaths worldwide. In order to further investigate …
View article: Culturomics reveals a hidden world of vaginal microbiota with the isolation of 206 bacteria from a single vaginal sample
Culturomics reveals a hidden world of vaginal microbiota with the isolation of 206 bacteria from a single vaginal sample Open
The composition of the vaginal microbiota is known to be influenced by various factors and to be associated with several disorders affecting women’s health. Although metagenomics is currently a widely used method for studying the human mic…
View article: Antibiotic activity of fungus comb extract from fungus-farming termites
Antibiotic activity of fungus comb extract from fungus-farming termites Open
Termites, predominantly abundant in Africa, represent eusocial insects with a significant ecological role. They have historically served as valuable natural resources in various domains, including traditional medicine, human dietary practi…
View article: Erythema Migrans Caused by <i>Borrelia spielmanii</i>, France
Erythema Migrans Caused by <i>Borrelia spielmanii</i>, France Open
We describe a rare case of early Lyme borreliosis in France caused by Borrelia spielmanii, which manifested as a large erythema chronicum migrans rash. The patient completely recovered after a 15-day course of amoxicillin. Absence of patho…
View article: Relationship between Bacterial Vaginosis and Sexually Transmitted Infections: Coincidence, Consequence or Co-Transmission?
Relationship between Bacterial Vaginosis and Sexually Transmitted Infections: Coincidence, Consequence or Co-Transmission? Open
Sexually transmitted infections (STIs) are a serious global problem, causing disease, suffering, and death. Although bacterial vaginosis (BV) is not considered to be an STI, it may be associated with an increased risk of contracting a wide…
View article: The Emergence of Carbapenem- and Colistin-Resistant Enterobacteria in Senegal
The Emergence of Carbapenem- and Colistin-Resistant Enterobacteria in Senegal Open
Antibiotic resistance is a public health problem. The emergence of carbapenemase-producing Enterobacterales (CPE) infections is a concern, particularly in Senegal. (1) Methods: Between January 2019 and July 2022, 240 isolates of enterobact…
View article: Molecular Survey of Rodent-Borne Infectious Agents in the Ferlo Region, Senegal
Molecular Survey of Rodent-Borne Infectious Agents in the Ferlo Region, Senegal Open
Zoonotic pathogens are responsible for most infectious diseases in humans, with rodents being important reservoir hosts for many of these microorganisms. Rodents, thus, pose a significant threat to public health. Previous studies in Senega…
View article: New Genotype of <i>Coxiella burnetii</i> Causing Epizootic Q Fever Outbreak in Rodents, Northern Senegal
New Genotype of <i>Coxiella burnetii</i> Causing Epizootic Q Fever Outbreak in Rodents, Northern Senegal Open
In Senegal, Coxiella burnetii, which causes Q fever, has often been identified in ticks and humans near livestock, which are considered to be reservoirs and main sources of infection. We describe the emergence of C. burnetii in rodents, no…
View article: Habitat mosaic as a driver of the resilience of native species: The case of the assemblage of small mammals from the city of Franceville, Gabon
Habitat mosaic as a driver of the resilience of native species: The case of the assemblage of small mammals from the city of Franceville, Gabon Open
Rodents (Rodentia) are the most abundant and diverse order of mammals, present in all habitats, including urban areas. The traffic linked to globalisation has favoured their involvement in biological invasions that have an impact on local …
View article: Genome-wide analysis of the human head louse (Pediculus humanus capitis) reveals geographically structured genetic populations
Genome-wide analysis of the human head louse (Pediculus humanus capitis) reveals geographically structured genetic populations Open
The human head louse ( Pediculus humanus capitis ) is an obligate ectoparasite of humans and has the potential to uncover aspects of human history that cannot be directly inferred from genetic data derived from humans. Previous studies hav…
View article: Contribution of point-of-care laboratories in the molecular diagnosis and monitoring of COVID-19 in Niakhar, Dielmo and Ndiop rural areas in Senegal
Contribution of point-of-care laboratories in the molecular diagnosis and monitoring of COVID-19 in Niakhar, Dielmo and Ndiop rural areas in Senegal Open
• POC laboratories have demonstrated their usefulness in the context of a pandemic (like COVID-19). • The movement of population during major events likely contributed to the spread of SARS-CoV-2 and its variants. • The persistence of the …
View article: Borrelia miyamotoi in wild rodents from four different regions of Turkey
Borrelia miyamotoi in wild rodents from four different regions of Turkey Open
Borrelia miyamotoi is a tick-borne zoonotic agent that causes hard tick-borne relapsing fever, an emerging disease in humans. Some small mammalian and bird species are reported to be reservoirs of B. miyamotoi. This study aims to examine B…
View article: Carbonyl Cyanide 3-Chloro Phenyl Hydrazone (CCCP) Restores the Colistin Sensitivity in Brucella intermedia
Carbonyl Cyanide 3-Chloro Phenyl Hydrazone (CCCP) Restores the Colistin Sensitivity in Brucella intermedia Open
Brucella intermedia (formerly Ochrobactrum intermedium), a non-fermentative bacterium, has been isolated from animals and human clinical specimens. It is naturally resistant to polymyxins, including colistin (CO), and may cause opportunist…