Andreas Wanisch
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View article: <i>Helicobacter pylori</i> γ-glutamyltransferase is linked to proteomic adaptions important for colonization
<i>Helicobacter pylori</i> γ-glutamyltransferase is linked to proteomic adaptions important for colonization Open
Helicobacter pylori γ-glutamyltransferase (gGT) is a virulence factor that promotes bacterial colonization and immune tolerance. Although some studies addressed potential functional mechanisms, the supportive role of gGT for in vivo coloni…
View article: <i>Helicobacter pylori</i>γ-glutamyltransferase relates to proteomic adaptions important for gastric colonization
<i>Helicobacter pylori</i>γ-glutamyltransferase relates to proteomic adaptions important for gastric colonization Open
Helicobacter pylori γ-glutamyltransferase (gGT) is a virulence factor that promotes bacterial colonization and immune tolerance. Although some studies addressed potential functional mechanisms, the supportive role of gGT for in-vivo coloni…
View article: <i>Helicobacter pylori</i> promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature
<i>Helicobacter pylori</i> promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature Open
Objective Helicobacter pylori infection is the most prevalent bacterial infection worldwide. Besides being the most important risk factor for gastric cancer development, epidemiological data show that infected individuals harbour a nearly …
Long-term persistence and functionality of adoptively transferred antigen-specific T cells with genetically ablated PD-1 expression Open
Engagement of the inhibitory T cell receptor programmed cell death protein 1 (PD-1) associates with dysfunctional states of pathogen- or tumor-specific T cells. Accordingly, systemic antibody-mediated blockade of PD-1 has become a central …
View article: <i>Helicobacter pylori</i> promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature
<i>Helicobacter pylori</i> promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature Open
OBJECTIVE H. pylori infection is the most prevalent bacterial infection worldwide. Besides being the most important risk factor for gastric cancer development, epidemiological data show that infected individuals harbor a nearly two-fold in…
Increased LIGHT expression and activation of non-canonical NF-κB are observed in gastric lesions of MyD88-deficient mice upon Helicobacter felis infection Open
Helicobacter pylori infection induces a number of pro-inflammatory signaling pathways contributing to gastric inflammation and carcinogenesis. Among those, NF-κB signaling plays a pivotal role during infection and malignant transformation …
Helicobacter pylori γ-glutamyl transferase contributes to colonization and differential recruitment of T cells during persistence Open
Helicobacter pylori γ-glutamyl transferase (gGT) is a key bacterial virulence factor that is not only important for bacterial gastric colonization but also related to the development of gastric pathology. Despite accumulating evidence for …