Andreea-Elena Scheau
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View article: Advances in 3D-Printed Drug Delivery and Screening Platforms for Bone Disease Therapy
Advances in 3D-Printed Drug Delivery and Screening Platforms for Bone Disease Therapy Open
Bone diseases such as osteomyelitis, osteosarcoma, and osteoarthritis, as well as conditions caused by metabolic imbalances, including osteoporosis, require more efficient and optimized therapies. Systemic drug administration entails major…
View article: The Multifaceted Antimicrobial Profile of Piperine in Infectious Disease Management: Current Perspectives and Potential
The Multifaceted Antimicrobial Profile of Piperine in Infectious Disease Management: Current Perspectives and Potential Open
Piperine is an alkaloid found in plants of the genus Piper, and particularly in P. nigrum. This compound has been under extensive research lately for its antimicrobial, antiviral, and also anti-inflammatory, anti-oxidant, anticancer, and p…
View article: Head and Neck 3D Bioprinting—A Review on Recent Advancements in Soft Tissue 3D Bioprinting and Medical Applications
Head and Neck 3D Bioprinting—A Review on Recent Advancements in Soft Tissue 3D Bioprinting and Medical Applications Open
Recent developments in 3D bioprinting offer innovative alternative solutions to classical treatments for head and neck defects. Soft tissues in an anatomical area as diverse in composition as the head and neck are complex in terms of struc…
View article: Pinosylvin: A Multifunctional Stilbenoid with Antimicrobial, Antioxidant, and Anti-Inflammatory Potential
Pinosylvin: A Multifunctional Stilbenoid with Antimicrobial, Antioxidant, and Anti-Inflammatory Potential Open
Stilbenoids are a category of plant compounds exhibiting notable health-related benefits. After resveratrol, perhaps the most well-known stilbenoid is pinosylvin, a major phytochemical constituent of most plants characterised by the pine s…
View article: The Cross-Talk Between the Peripheral and Brain Cholesterol Metabolisms
The Cross-Talk Between the Peripheral and Brain Cholesterol Metabolisms Open
Cholesterol is an essential element for the development and normal function of the central nervous system. While peripheral cholesterol is influenced by liver metabolism and diet, brain cholesterol metabolism takes place in an isolated sys…
View article: Role of computed tomography in gastrointestinal lymphoma: diagnosis, monitoring and complications
Role of computed tomography in gastrointestinal lymphoma: diagnosis, monitoring and complications Open
View article: 3D Bioprinting in Limb Salvage Surgery
3D Bioprinting in Limb Salvage Surgery Open
With the development of 3D bioprinting and the creation of innovative biocompatible materials, several new approaches have brought advantages to patients and surgical teams. Increasingly more bone defects are now treated using 3D-bioprinte…
View article: Non-Surgical Treatment for Hepatocellular Carcinoma: What to Expect at Follow-Up Magnetic Resonance Imaging—A Pictorial Review
Non-Surgical Treatment for Hepatocellular Carcinoma: What to Expect at Follow-Up Magnetic Resonance Imaging—A Pictorial Review Open
Hepatocellular carcinoma (HCC), the most prevalent form of liver cancer, represents a significant global health challenge due to its rising incidence, complex management, as well as recurrence rates of up to 70% or more. Early and accurate…
View article: Agonists, Antagonists and Receptors of Somatostatin: Pathophysiological and Therapeutical Implications in Neoplasias
Agonists, Antagonists and Receptors of Somatostatin: Pathophysiological and Therapeutical Implications in Neoplasias Open
Somatostatin is a peptide that plays a variety of roles such as neurotransmitter and endocrine regulator; its actions as a cell regulator in various tissues of the human body are represented mainly by inhibitory effects, and it shows poten…
View article: Capsaicin: Emerging Pharmacological and Therapeutic Insights
Capsaicin: Emerging Pharmacological and Therapeutic Insights Open
Capsaicin, the most prominent pungent compound of chilli peppers, has been used in traditional medicine systems for centuries; it already has a number of established clinical and industrial applications. Capsaicin is known to act through t…
View article: The Interplay between Obesity and Inflammation
The Interplay between Obesity and Inflammation Open
Obesity is an important condition affecting the quality of life of numerous patients and increasing their associated risk for multiple diseases, including tumors and immune-mediated disorders. Inflammation appears to play a major role in t…
View article: Use of Biomaterials in 3D Printing as a Solution to Microbial Infections in Arthroplasty and Osseous Reconstruction
Use of Biomaterials in 3D Printing as a Solution to Microbial Infections in Arthroplasty and Osseous Reconstruction Open
The incidence of microbial infections in orthopedic prosthetic surgeries is a perennial problem that increases morbidity and mortality, representing one of the major complications of such medical interventions. The emergence of novel techn…
View article: Biomaterials Adapted to Vat Photopolymerization in 3D Printing: Characteristics and Medical Applications
Biomaterials Adapted to Vat Photopolymerization in 3D Printing: Characteristics and Medical Applications Open
Along with the rapid and extensive advancements in the 3D printing field, a diverse range of uses for 3D printing have appeared in the spectrum of medical applications. Vat photopolymerization (VPP) stands out as one of the most extensivel…
View article: Kaempferol: A Review of Current Evidence of Its Antiviral Potential
Kaempferol: A Review of Current Evidence of Its Antiviral Potential Open
Kaempferol and its derivatives are flavonoids found in various plants, and a considerable number of these have been used in various medical applications worldwide. Kaempferol and its compounds have well-known antioxidant, anti-inflammatory…
View article: Hematologic Malignancies Diagnosed in the Context of the mRNA COVID-19 Vaccination Campaign: A Report of Two Cases
Hematologic Malignancies Diagnosed in the Context of the mRNA COVID-19 Vaccination Campaign: A Report of Two Cases Open
Background: During the last two years, the COVID-19 pandemic led to millions of disease-related deaths worldwide. The efforts of the scientific community facing this global challenge resulted in outstanding achievements. Thus, within one y…
View article: Availability, Toxicology and Medical Significance of Antimony
Availability, Toxicology and Medical Significance of Antimony Open
Antimony has been known and used since ancient times, but its applications have increased significantly during the last two centuries. Aside from its few medical applications, it also has industrial applications, acting as a flame retardan…
View article: Antitumoral and Anti-inflammatory Roles of Somatostatin and Its Analogs in Hepatocellular Carcinoma
Antitumoral and Anti-inflammatory Roles of Somatostatin and Its Analogs in Hepatocellular Carcinoma Open
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and affects about 8% of cirrhotic patients, with a recurrence rate of over 50%. There are numerous therapies available for the treatment of HCC, depending on cancer sta…
View article: Cannabinoids and Inflammations of the Gut-Lung-Skin Barrier
Cannabinoids and Inflammations of the Gut-Lung-Skin Barrier Open
Recent studies have identified great similarities and interferences between the epithelial layers of the digestive tract, the airways and the cutaneous layer. The relationship between these structures seems to implicate signaling pathways,…
View article: The Effects of Capsaicin on Gastrointestinal Cancers
The Effects of Capsaicin on Gastrointestinal Cancers Open
Gastrointestinal (GI) cancers are a group of diseases with very high positions in the ranking of cancer incidence and mortality. While they show common features regarding the molecular mechanisms involved in cancer development, organ-speci…
View article: Cannabinoids in the Pathophysiology of Skin Inflammation
Cannabinoids in the Pathophysiology of Skin Inflammation Open
Cannabinoids are increasingly-used substances in the treatment of chronic pain, some neuropsychiatric disorders and more recently, skin disorders with an inflammatory component. However, various studies cite conflicting results concerning …
View article: Lipiodol Uptake and Wash-out Rate Detection on Computed Tomography as Predictors for Tumor Recurrence in Hepatocellular Carcinoma Treated by Transcatheter Arterial Chemoembolization
Lipiodol Uptake and Wash-out Rate Detection on Computed Tomography as Predictors for Tumor Recurrence in Hepatocellular Carcinoma Treated by Transcatheter Arterial Chemoembolization Open
Background: Transcatheter arterial chemoembolization (TACE) is a dedicated method for treating intermediate stage hepatocellular carcinoma (HCC).The Lipiodol used in conventional TACE presents the advantage of being easily visualized and q…