Andrej Belančić
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View article: Nonadherence and uncontrolled arterial hypertension in Croatia—Insights from the <i>May Measurement Month 2023</i> campaign and <i>Hunting the silent killer</i> programme
Nonadherence and uncontrolled arterial hypertension in Croatia—Insights from the <i>May Measurement Month 2023</i> campaign and <i>Hunting the silent killer</i> programme Open
Aims To determine the prevalence of non‐adherence to antihypertensive medicines and to identify demographic and behavioral factors associated with non‐adherence in subjects enrolled in the May Measurement Month (MMM) 2023, as part of the p…
View article: Diverging Safety Signals: A Trend Analysis of Suspected Adverse Drug Reactions Reporting for Spinal Muscular Atrophy Therapies in the European Union
Diverging Safety Signals: A Trend Analysis of Suspected Adverse Drug Reactions Reporting for Spinal Muscular Atrophy Therapies in the European Union Open
Background/Objectives: The approval of disease-modifying therapies has significantly improved outcomes for patients with spinal muscular atrophy (SMA), yet their long-term safety profiles remain under continuous evaluation. This study aime…
View article: Effects of Janus Kinase Inhibitors on Rheumatoid Arthritis Pain: Clinical Evidence and Mechanistic Pathways
Effects of Janus Kinase Inhibitors on Rheumatoid Arthritis Pain: Clinical Evidence and Mechanistic Pathways Open
Pain remains one of the most burdensome symptoms in rheumatoid arthritis (RA), often persisting despite inflammatory remission and profoundly impairing quality of life. This review aimed to evaluate the clinical efficacy and mechanistic pa…
View article: Methodological considerations on paracetamol pharmacokinetics in spinal muscular atrophy: A response to Zhao et al.
Methodological considerations on paracetamol pharmacokinetics in spinal muscular atrophy: A response to Zhao et al. Open
View article: Utilization of Child-Appropriate Medicines: Use of Pediatric Use Marketing Authorisation (PUMA) Products in Croatia
Utilization of Child-Appropriate Medicines: Use of Pediatric Use Marketing Authorisation (PUMA) Products in Croatia Open
Background/Objectives: Children remain underserved in pharmaceutical development, with off-label prescribing still prevalent in part due to a lack of age-appropriate formulations. This study aimed to evaluate the national uptake of Pediatr…
View article: Closing the Evidence Gap: Retrospective and Prospective Strategies to Advance Aripiprazole's Potential Benefits in Patients With Cancer
Closing the Evidence Gap: Retrospective and Prospective Strategies to Advance Aripiprazole's Potential Benefits in Patients With Cancer Open
View article: Transforming Spinal Muscular Atrophy: From Pivotal Trials to Real-World Evidence and Future Therapeutic Frontiers in Types 1 and 2
Transforming Spinal Muscular Atrophy: From Pivotal Trials to Real-World Evidence and Future Therapeutic Frontiers in Types 1 and 2 Open
Spinal muscular atrophy (SMA) is a rare, autosomal recessive neuromuscular disorder and a leading genetic cause of infant mortality. The past decade has witnessed a paradigm shift in SMA management with the advent of disease-modifying drug…
View article: Recent Advances in the Therapeutic Potential of Cannabinoids Against Gliomas: A Systematic Review (2022–2025)
Recent Advances in the Therapeutic Potential of Cannabinoids Against Gliomas: A Systematic Review (2022–2025) Open
Glioma is the most common and lethal primary brain tumor in adults, with glioblastoma (GBM) representing the most aggressive subtype, characterized by diffuse infiltration, resistance to therapy, and a poor prognosis. Despite standard trea…
View article: Prenatal Management of Spinal Muscular Atrophy in the Era of Genetic Screening and Emerging Opportunities in In Utero Therapy
Prenatal Management of Spinal Muscular Atrophy in the Era of Genetic Screening and Emerging Opportunities in In Utero Therapy Open
Spinal muscular atrophy (SMA) is a severe autosomal recessive neuromuscular disorder and a leading genetic cause of infant mortality. Advances in disease-modifying therapies have significantly improved outcomes when treatment is initiated …
View article: Comparing the Impact of Different Antiarrhythmic Classes on Clinical Outcomes Following Atrial Fibrillation Catheter Ablation
Comparing the Impact of Different Antiarrhythmic Classes on Clinical Outcomes Following Atrial Fibrillation Catheter Ablation Open
Background/Objectives: Catheter ablation has become the standard of care for patients with symptomatic and drug-refractory atrial fibrillation (AF). Both Class IC and Class III antiarrhythmic drugs (AADs) are effective in preventing early …
View article: Aspirin Versus <scp>LMWH</scp> for Thromboprophylaxis Following Hip or Knee Arthroplasty—Clinical Implications and Budget Impact
Aspirin Versus <span>LMWH</span> for Thromboprophylaxis Following Hip or Knee Arthroplasty—Clinical Implications and Budget Impact Open
Venous thromboembolism (VTE) remains a significant concern for patients undergoing hip or knee arthroplasty, with a need to balance effective thromboprophylaxis and bleeding risk. We aimed to compare the efficacy, safety, and budget impact…
View article: The impact of biological interventions on health-related quality of life in adults with Crohn's disease: a systematic review with meta-analysis
The impact of biological interventions on health-related quality of life in adults with Crohn's disease: a systematic review with meta-analysis Open
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View article: Ultra-Processed Diets and Endocrine Disruption, Explanation of Missing Link in Rising Cancer Incidence Among Young Adults
Ultra-Processed Diets and Endocrine Disruption, Explanation of Missing Link in Rising Cancer Incidence Among Young Adults Open
The global increase in early-onset cancers among adolescents and young adults has happened at the same time as the rise in the consumption of ultra-processed foods (UPFs). Far beyond their poor nutritional quality, UPFs are increasingly se…
View article: The Risk of Type 2 Diabetes Mellitus: Cardiorenometabolic Syndrome and Its Components—A Call to Action
The Risk of Type 2 Diabetes Mellitus: Cardiorenometabolic Syndrome and Its Components—A Call to Action Open
Cardiorenometabolic syndrome, a constellation of interrelated risk factors including insulin resistance, central obesity, dyslipidemia, and hypertension, is rapidly becoming one of the defining global health challenges of our time [...]
View article: Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes
Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes Open
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical respons…
View article: Bridging Clinical Outcomes and Cost‐Effectiveness: The Role of Real‐World Data in Cystic Fibrosis Therapy
Bridging Clinical Outcomes and Cost‐Effectiveness: The Role of Real‐World Data in Cystic Fibrosis Therapy Open
View article: A time series analysis approach to quantify change in antibiotic resistance and antibiotic consumption during COVID-19 epidemics: a multicentre cross-national ecological study on behalf of QUantifying change in Antibiotic Resistance, ANTibiotic use, and INfection control during COVID-19 Epidemics study project
A time series analysis approach to quantify change in antibiotic resistance and antibiotic consumption during COVID-19 epidemics: a multicentre cross-national ecological study on behalf of QUantifying change in Antibiotic Resistance, ANTibiotic use, and INfection control during COVID-19 Epidemics study project Open
The COVID-19 pandemic was associated with higher usage of broad-spectrum antibiotics and higher incidence of multidrug-resistant bacteria, with great variability by countries. These results could support international action plans that emb…
View article: Costs of Treating Onasemnogene Abeparvovec‐Xioi‐Induced Liver Injury
Costs of Treating Onasemnogene Abeparvovec‐Xioi‐Induced Liver Injury Open
Aims were to reveal types of onasemnogene abeparvovec‐xioi ( OA )‐induced liver injury, their treatment patterns, utilization of healthcare, and treatment costs. This study employed secondary research to analyze OA ‐induced liver injury us…
View article: Traumatic Brain Injury: Novel Experimental Approaches and Treatment Possibilities
Traumatic Brain Injury: Novel Experimental Approaches and Treatment Possibilities Open
Traumatic brain injury (TBI) remains a critical global health issue with limited effective treatments. Traditional care of TBI patients focuses on stabilization and symptom management without regenerating damaged brain tissue. In this revi…
View article: Trends in Lipid‐Lowering Agent Consumption in Croatia: A 25‐Year Observational Study
Trends in Lipid‐Lowering Agent Consumption in Croatia: A 25‐Year Observational Study Open
Cardiovascular diseases are the leading cause of mortality worldwide, with dyslipidemia as a major modifiable risk factor. This study aimed to assess 25‐year trends in lipid‐lowering agent consumption in Croatia from 2000 to 2023. We condu…
View article: The Mechanisms of Chronic Inflammation in Obesity and Potential Therapeutic Strategies: A Narrative Review
The Mechanisms of Chronic Inflammation in Obesity and Potential Therapeutic Strategies: A Narrative Review Open
Obesity, a global health concern of increasing significance, is characterized by chronic low-grade inflammation (LGCI) that significantly contributes to metabolic dysfunction. This narrative review explores the intricate pathophysiological…
View article: Post-Marketing Safety of Spinal Muscular Atrophy Therapies: Analysis of Spontaneous Adverse Drug Reactions from EudraVigilance
Post-Marketing Safety of Spinal Muscular Atrophy Therapies: Analysis of Spontaneous Adverse Drug Reactions from EudraVigilance Open
Background/Objectives: Spinal muscular atrophy (SMA) treatment has evolved with the approval of nusinersen, onasemnogene abeparvovec, and risdiplam. This study aims to assess the post-marketing safety profile of these therapies through the…
View article: Time for Change: A 3-Year Prospective Study on Mediterranean Diet Adherence and Body Composition in Kidney Transplant Recipients
Time for Change: A 3-Year Prospective Study on Mediterranean Diet Adherence and Body Composition in Kidney Transplant Recipients Open
Background: The aim of this prospective follow-up study was to evaluate changes in body composition parameters and Mediterranean diet (MeDi) adherence among kidney transplant recipients (KTRs) over a three-year period. Additionally, this s…
View article: A Narrative Review on the Risk Factors and Healthcare Disparities of Type 2 Diabetes
A Narrative Review on the Risk Factors and Healthcare Disparities of Type 2 Diabetes Open
Type 2 diabetes (T2D) is a rapidly growing global health concern, projected to affect 1.3 billion people by 2050, necessitating a multidisciplinary approach. This review examines the epidemiological disparities in T2D, focusing on modifiab…
View article: Cardiometabolic Risk in Psoriatic Arthritis: A Hidden Burden of Inflammation and Metabolic Dysregulation
Cardiometabolic Risk in Psoriatic Arthritis: A Hidden Burden of Inflammation and Metabolic Dysregulation Open
Psoriatic arthritis (PsA) is a chronic inflammatory disease that extends beyond musculoskeletal and dermatologic involvement to elevate cardiometabolic risk. Emerging evidence highlights the critical role of systemic inflammation in metabo…
View article: Glial Cells in Spinal Muscular Atrophy: Speculations on Non-Cell-Autonomous Mechanisms and Therapeutic Implications
Glial Cells in Spinal Muscular Atrophy: Speculations on Non-Cell-Autonomous Mechanisms and Therapeutic Implications Open
Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by homozygous deletions or mutations in the SMN1 gene, leading to progressive motor neuron degeneration. While SMA has been classically viewed as a motor neuron-autonomous di…
View article: Clinic, Ambulatory and Home Blood Pressure Monitoring for Metabolic Syndrome: Time to Change the Definition?
Clinic, Ambulatory and Home Blood Pressure Monitoring for Metabolic Syndrome: Time to Change the Definition? Open
Background and Objectives: Metabolic syndrome (MetS) is considered a global epidemic, and its diagnosis is crucial, allowing early intervention and management. The main aim of this study was to examine any possible blood pressure (BP) diff…
View article: Analysis of Reporting Trends of Serious Adverse Events Associated With Anti‐Obesity Drugs
Analysis of Reporting Trends of Serious Adverse Events Associated With Anti‐Obesity Drugs Open
Concern over the side effects of anti‐obesity medications, particularly if severe, has grown as their use has increased. Thus, the objective was to use trends in the reporting of suspected adverse events associated with anti‐obesity medica…
View article: Navigating challenges and opportunities in orphan medicines: A spotlight commentary on rare diseases
Navigating challenges and opportunities in orphan medicines: A spotlight commentary on rare diseases Open
View article: Spotlight commentary: Changes in pharmacokinetics following significant weight loss
Spotlight commentary: Changes in pharmacokinetics following significant weight loss Open