Andrés G. Lescano
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View article: A multidimensional analysis of the risk of infection with Ehrlichia canis among urban dogs in Iquitos, Peru
A multidimensional analysis of the risk of infection with Ehrlichia canis among urban dogs in Iquitos, Peru Open
Ehrlichia canis is a tick-borne bacterium that causes a potentially fatal disease in dogs called canine monocytic ehrlichiosis. In this cross-sectional study, we used a One Health framework to identify statistical associations between E. c…
View article: The 2025 Lancet Countdown Latin America report: moving from promises to equitable climate action for a prosperous future
The 2025 Lancet Countdown Latin America report: moving from promises to equitable climate action for a prosperous future Open
View article: A multidimensional analysis of the risk of infection with <i>Ehrlichia canis</i> among urban dogs in Iquitos, Peru
A multidimensional analysis of the risk of infection with <i>Ehrlichia canis</i> among urban dogs in Iquitos, Peru Open
Ehrlichia canis is a tick-borne bacterium that causes a potentially fatal disease in dogs called Canine Monocytic Ehrlichiosis. In this cross-sectional study, we used a One Health framework to identify statistical associations between E. c…
View article: Global assessment of partial artemisinin resistance: multicenter trial across Kenya, Peru, and Thailand in patients with uncomplicated Plasmodium falciparum malaria
Global assessment of partial artemisinin resistance: multicenter trial across Kenya, Peru, and Thailand in patients with uncomplicated Plasmodium falciparum malaria Open
This is the first concurrent evaluation of artemisinin resistance across three continents. The presence of 11% Thai subjects who satisfied WHO criteria for drug resistance establishes this area as endemic. Longer PC1/2 found in …
View article: Characterizing trachoma elimination using serology
Characterizing trachoma elimination using serology Open
Trachoma is targeted for global elimination as a public health problem by 2030. Measurement of IgG antibodies in children is being considered for surveillance and programmatic decision-making. There are currently no programmatic guidelines…
View article: “Beyond the flood: Exploring the psychosocial consequences and resilience challenges in the aftermath of “El Niño” in Tumbes, Peru”
“Beyond the flood: Exploring the psychosocial consequences and resilience challenges in the aftermath of “El Niño” in Tumbes, Peru” Open
View article: Dual Biomarker Potential of 18F-PR04.MZ-PET: Assessing Dopaminergic Function and Cerebral Blood Flow in Degenerative Parkinsonian Syndromes
Dual Biomarker Potential of 18F-PR04.MZ-PET: Assessing Dopaminergic Function and Cerebral Blood Flow in Degenerative Parkinsonian Syndromes Open
Objective 18F-PR04.MZ is a new PET radiopharmaceutical for the dopamine transporter (DAT), characterized by enhanced affinity and selectivity for this membrane protein. Previous investigations employing various radiotracers in d…
View article: Proactive One-Health surveillance reveals novel orthobunyaviruses and their potential vectors and reservoirs
Proactive One-Health surveillance reveals novel orthobunyaviruses and their potential vectors and reservoirs Open
Mosquito-borne viruses pose a significant, global threat to human and animal health. Traditionally, arthropod-borne virus (arbovirus) surveillance has been retroactive following an outbreak, which limits the ability to predict and prevent …
View article: Sex differences in the diagnosis latency of Parkinson's disease in Latin America
Sex differences in the diagnosis latency of Parkinson's disease in Latin America Open
Our results suggest that there may be country and age dependent sex differences in AAO, AAD, and diagnosis latency of PD in Latin America. Interestingly, the mean AAO of LARGE-PD is approximately 6 years younger than studies done with Euro…
View article: Monitoring of Selected Swine Viral Diseases in Peruvian Amazon Peccaries
Monitoring of Selected Swine Viral Diseases in Peruvian Amazon Peccaries Open
Peccaries (collared peccary—CP—and white-lipped peccary—WLP) are an essential source of protein and income for rural communities in the Amazon region. Since 1980s, researchers in the Amazon have reported recurrent local disappearances of W…
View article: Body Mass Index and Bronchodilator Responsiveness in Adults: Analysis of 2 Population-Based Studies in 4 South American Countries
Body Mass Index and Bronchodilator Responsiveness in Adults: Analysis of 2 Population-Based Studies in 4 South American Countries Open
There was a differential relationship between BMI and types of BDR: higher BMI was associated with FVC-specific responsiveness, whereas lower BMI was linked to FEV₁-specific BDR in individuals with asthma and chronic bronchitis and to over…
View article: Comparing the Generalizability of Multi-Regional versus Locally Trained Deep Learning Models for Trachoma Detection
Comparing the Generalizability of Multi-Regional versus Locally Trained Deep Learning Models for Trachoma Detection Open
View article: Climate Change, Health, and Migration in LAC
Climate Change, Health, and Migration in LAC Open
View article: Spotted fever group rickettsiae in black rats, pets, and humans in Zungarococha community, A rural area in the surroundings of Iquitos, Peru
Spotted fever group rickettsiae in black rats, pets, and humans in Zungarococha community, A rural area in the surroundings of Iquitos, Peru Open
View article: Highway paving increased dengue transmission in the Peruvian Amazon
Highway paving increased dengue transmission in the Peruvian Amazon Open
Human mobility drives the spread of many infectious diseases, yet the health impacts of mobility changes from new infrastructure development remain poorly understood and currently not accounted for in impact assessments. We present a novel…
View article: Genetics of Latin American Diversity Project: Insights into population genetics and association studies in admixed groups in the Americas
Genetics of Latin American Diversity Project: Insights into population genetics and association studies in admixed groups in the Americas Open
Latin Americans are underrepresented in genetic studies, increasing disparities in personalized genomic medicine. Despite available genetic data from thousands of Latin Americans, accessing and navigating the bureaucratic hurdles for conse…
View article: Extreme precipitation, exacerbated by anthropogenic climate change, drove Peru’s record-breaking 2023 dengue outbreak
Extreme precipitation, exacerbated by anthropogenic climate change, drove Peru’s record-breaking 2023 dengue outbreak Open
Anthropogenic forcing is increasing the likelihood and severity of certain extreme weather events, which may catalyze outbreaks of climate-sensitive infectious diseases. Extreme precipitation events can promote the spread of mosquito-borne…
View article: Biofilm formation and increased mortality among cancer patients with candidemia in a Peruvian reference center
Biofilm formation and increased mortality among cancer patients with candidemia in a Peruvian reference center Open
The association between candidemia with in vitro biofilm formation and an increased risk of death consistently observed both in patients with and without treatment, provides another level of evidence for a possible causal association. The …
View article: Genetics of Latin American Diversity Project: Insights into population genetics and association studies in admixed groups in the Americas
Genetics of Latin American Diversity Project: Insights into population genetics and association studies in admixed groups in the Americas Open
View article: Characterizing trachoma elimination using serology
Characterizing trachoma elimination using serology Open
Trachoma is targeted for global elimination as a public health problem by 2030. Measurement of IgG antibodies in children is being considered for surveillance and programmatic decision-making. There are currently no guidelines for applicat…
View article: A Survey of Hepatitis B Virus and Hepatitis E Virus at the Human–Wildlife Interface in the Peruvian Amazon
A Survey of Hepatitis B Virus and Hepatitis E Virus at the Human–Wildlife Interface in the Peruvian Amazon Open
Hepatitis B virus (HBV) and Hepatitis E virus (HEV) are zoonotic pathogens posing significant health concerns in rural Amazonia, a region marked by high endemicity, poverty, and limited healthcare access. However, the epidemiology of HBV a…
View article: Mass chemotherapy with niclosamide for the control of Taenia solium: population-based safety profile and treatment effectiveness
Mass chemotherapy with niclosamide for the control of Taenia solium: population-based safety profile and treatment effectiveness Open
View article: The 2023 Latin America report of The Lancet Countdown on health and climate change
The 2023 Latin America report of The Lancet Countdown on health and climate change Open
View article: Cost-effectiveness of COVID rapid diagnostic tests for patients with severe/critical illness in low- and middle-income countries: A modeling study
Cost-effectiveness of COVID rapid diagnostic tests for patients with severe/critical illness in low- and middle-income countries: A modeling study Open
Background Rapid diagnostic tests (RDTs) for coronavirus disease (COVID) are used in low- and middle-income countries (LMICs) to inform treatment decisions. However, to date, it is unclear when this use is cost-effective. Existing analyses…
View article: Unravelling heterogeneous malaria transmission dynamics in the Peruvian Amazon: insights from a cross-sectional survey
Unravelling heterogeneous malaria transmission dynamics in the Peruvian Amazon: insights from a cross-sectional survey Open
Background Malaria remains a global health challenge, particularly in Peru's Loreto region. Despite ongoing efforts, high infection rates and asymptomatic cases perpetuate transmission. The Peruvian Ministry of Health’s “Zero Malaria Plan”…
View article: Building global preparedness for avian influenza
Building global preparedness for avian influenza Open
View article: Unraveling Heterogeneous Malaria Transmission Dynamics in the Peruvian Amazon: Insights from a Cross-Sectional Survey
Unraveling Heterogeneous Malaria Transmission Dynamics in the Peruvian Amazon: Insights from a Cross-Sectional Survey Open
Background Malaria continues to pose a significant public health challenge in the Loreto region of the Peruvian Amazon, prompting the implementation of the "Plan Malaria Cero" to minimize cases and eliminate malaria in the region. However,…
View article: Circulation of DENV-2 serotype associated with increased risk of cumulative incidence of severe dengue and dengue with warning signs: A 16-year retrospective study in Peru
Circulation of DENV-2 serotype associated with increased risk of cumulative incidence of severe dengue and dengue with warning signs: A 16-year retrospective study in Peru Open
Background Dengue poses a significant public health challenge in Peru and other endemic countries worldwide. While severe dengue is known to be associated with secondary infection at the individual level, the factors that elevate the risk …
View article: Toxoplasma gondii in a Remote Subsistence Hunting-Based Indigenous Community of the Peruvian Amazon
Toxoplasma gondii in a Remote Subsistence Hunting-Based Indigenous Community of the Peruvian Amazon Open
Toxoplasma gondii is a ubiquitous zoonotic protozoan parasite that infects a wide variety range of warm-blooded animals. This study describes the epidemiological scenario of T. gondii in an indigenous community that relies on subsistence h…
View article: The 2023 Latin America report of the Lancet Countdown on health and climate change: the imperative for health-centred climate-resilient development
The 2023 Latin America report of the Lancet Countdown on health and climate change: the imperative for health-centred climate-resilient development Open